Prognostic Factors in Electric Convulsive Therapy

Hobson, Robert F.

doi:10.1136/jnnp.16.4.275

Cited by 110 publications

(25 citation statements)

References 10 publications

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“…17,18,20,24,25,43,48 In these studies, traits such as neuroticism, emotional lability, histrionic attitude, and the like, did predict less optimal ECT outcomes. Unfortunately, this early line of research has not been followed up.…”

Section: Methodologic Problems Of the Ect/melancholia Literature And mentioning

confidence: 97%

Electroconvulsive Therapy and Melancholia

Rasmussen

2011

The Journal of ECT

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It has long been lore in the electroconvulsive therapy (ECT) field that melancholic depression is particularly responsive to ECT, whereas nonmelancholic depressions are less so. Early large case series in the 1940s and 1950s, while using now outdated diagnostic nosologies, did provide some hints to the particular efficacy of what later on would be considered melancholic or endogenous depression. The first systematic studies of this subject in the 1950s and 1960s seemed to confirm the superior response of endogenous depression to ECT. However, with the advent of the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, and the first criterion set specifically labeled "melancholia," most modern series of studies have failed to find an association of melancholic symptoms with ECT response. Several problems both with the definition of melancholia and the modern methods of diagnosis and outcome assessment are hypothesized to be at the root of the negative findings of modern studies. Suggestions for future ECT/melancholia studies are offered.

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Section: Methodologic Problems Of the Ect/melancholia Literature And mentioning

confidence: 97%

Electroconvulsive Therapy and Melancholia

Rasmussen

2011

The Journal of ECT

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“…Hier zeigte sich allgemein eine starke Korrelation eines hohen HIS-Wertes mit negativem Therapieerfolg bzw. im Speziellen ein signifikant negativ prädiktiver Wert der Merkmale "Hypochondrie", "Depersonalisation", "Affektlabilität", "Hysterische Züge", "Neurotizismus im Erwachsenenalter" für die Response auf die EKT [11]. Diese Merkmale zeigen eine hohe Übereinstimmung mit der Cluster B Persönlichkeitsstruktur, aus der später die Abgrenzung der BPS erfolgte (DSM-III, 1980).…”

Section: Studien Vor Einführung Des Dsm-iiiunclassified

Elektrokrampftherapie bei Patienten mit Borderline-Persönlichkeitsstörung und schwerer Depression

Gescher¹,

Malevani²

2011

Fortschr Neurol Psychiatr

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Depressive disorder is a serious and frequent complication in borderline personality disorder (BPD), however, its severity tends to be neglected particularly if symptoms are short-lived or inconsistent as is common in patients with BPD. Yet the high frequency in these patients requires especially rapid and effective therapy to reduce the risks of vital endangerment, chronification and psychosocial impairment. Efficient crisis intervention is essential for continuity of the disease-specific multimodal therapy enabling lasting remission and social and vocational rehabilitation in BPD. In particular with regard to the high incidence of poor or failed pharmacological responses in patients with BPD, electroconvulsive therapy (ECT) is of significant relevance among antidepressant treatment options. Despite the wide consensus on its efficacy, there are only few selected trials on ECT for major depression (MD) in BPD. This review summarises the published original studies on this issue, and critically scrutinises indication, benefits and risks of ECT for MD in BPD. It contributes to a focused, discriminating view on ECT and thus enables an optimised patient-oriented, efficient indication for MD in BPD.

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“…Research into biological predictors of ECT response has been reviewed by Scott (1989), who concluded that 'There are no physiological measures or tests which are superior to clinical criteria in the selection of depressed patients for whom ECT would be an effective treatment'. A number of clinical scales have been produced to help predict response to ECT (eg Hobson, 1953;Roberts, 1959;Hamilton, 1974); perhaps the most widely used is the Newcastle scale (Carney et al, 1965). More recently, two double-blind trials of ECT focused attention on the predictive role of delusions (Crow et al, 1984;Brandon et al, 1984), the former study finding delusions to be 'the most significant and only consistent predictor of response to real ECT'.…”

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Which elderly depressives will respond to ECT?

Morris

1991

Int J Geriat Psychiatry

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SUMMARYRecent research has confirmed that ECT is an effective treatment for elderly patients with severe depressive illnesses, but not without some hazard in its administration. The currently available prognostic indicators for ECT have been developed in adults under 65 years old. In this study, the Newcastle ECT prediction scale, the presence of delusions and a scale developed in an elderly population are used to predict response to ECT in a group of 30 elderly depressives. Only the latter is shown to predict responses to ECT. The significance of these findings is discussed.

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Prognostic Factors in Electric Convulsive Therapy

Cited by 110 publications

References 10 publications

Electroconvulsive Therapy and Melancholia

Electroconvulsive Therapy and Melancholia

Elektrokrampftherapie bei Patienten mit Borderline-Persönlichkeitsstörung und schwerer Depression

Which elderly depressives will respond to ECT?

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