Prognostic factors for response to antibiotic therapy of low-grade gastric malt lymphoma: The importance of TNM staging by endoscopic ultrasonography

Fusaroli, Pietro; Buscarini, E.; Parente, F.; Federici, T.; Peyre, S; Bonanno, George A.; Angelis, Claudio De; Brosolo, P.; Amplatz, S; Meroni, Emanuele; Napolitano, Vincenzo; Tempesta, Alfonso; Oppezzi, M.; Pisani, Anna; Schiavo, Marcello; Trian, Thomas; Caletti, Giancarlo

doi:10.1016/s1590-8658(01)80176-6

Cited by 3 publications

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“…While the Italian experience (18,19) with 76 initial cases reports very successful eradication results as a function of staging (relevant remission for T1N0 stages), with an accuracy of 95%, sensitivity of 89%, and specificity of 97% for EUS in the staging procedure, such is not the case with the German experience (20). Fischbach et al (20), in a multicenter study of 80 cases with several work groups, conclude that EUS staging was only successful in 53% of cases, as EUS underestimates the diagnosis of adenopathies.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic staging of low-grade gastric malt lymphoma

Varas¹,

Fabra²,

Abad³

et al. 2006

Rev. esp. enferm. dig.

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Introduction: endoscopic ultrasonography (EUS) has already proven useful in the assessment of submucosal lesions, and the staging of gastrointestinal cancer, particularly gastric MALT-type lymphoma. The goal of this paper was EUS staging. Patients and method: 24 patients (10 females, 14 males) with a median age of 56 years and possibly gastric MALT lymphoma (25 cases) were studied using videoendoscopy, biopsies, and echoendoscopy with 7.5-and 20-MHz radial EUS, and also with 12-and 20-MHz miniprobes (MPs). Nineteen patients were definitely evaluated (7 females, 12 males) as having 20 MALT-type lymphomas, as five patients were post-hoc disregarded when an invasive, high-grade gastric lymphoma (3c) or plasmocytoma (2c) was subsequently demonstrated. Of these 19 patients, all had T1 lesions except for two with T2 lesions; one patient had a gastroduodenal T1 lymphoma. Echographic findings with MPs were compared to EUS (gold standard) and histology both before and after eradication. Then, patients were followed up every 1-3-6 months using videoendoscopy and MPs. Results: echoendoscopy correctly identified T stages in 90% of cases. MPs identified T stages in 88% of cases, and N stages in 33% of cases, with results being slightly inferior to those obtained with conventional EUS (91 vs. 45%); they were consequently used for follow-up. After eradication, all but two patients are in complete remission and have been followed every 1-3-6 months using MPs without echographic abnormalities, except for a patient who relapsed.

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Section: Discussionmentioning

confidence: 99%

Endoscopic staging of low-grade gastric malt lymphoma

Varas¹,

Fabra²,

Abad³

et al. 2006

Rev. esp. enferm. dig.

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“…Veliki broj radova i studija je objavljen na temu endosonografske procene za-hva}enosti pojedinih slojeva zida 'eluca MALT limfomom i EUS pra}enje bolesnika posle primenjene medikamentne terapije. Ve}ina se kao odgovor na efekat terapije oslanja samo na endosonografski nalaz 17,18 19 . Kriterijumi za uklju~ivanje u studiju su bili: low-grade primarni gastri~ni MALT limfom u stadijumu IE (IE1-IE2) ili IIE1 i helicobacter pozitivan status.…”

Section: Diskusijaunclassified

“…Sa prisustvom N1 ovaj procenat se znatno smanjivao. U stadijumu T2N1 niti jedan od bolesnika nije u{ao u kompletnu remisiju 19 . Sackmann i saradnici su objavili podatak da je postojala statisti~ki vrlo zna~ajna razlika, izmedju grupa tretiranih eradikacionom terapijom, kod kojih je dubina infiltracije zahvatala samo II i III sloj u poredjenju sa bolesnicima koji su imali dublju infiltraciju zida (te'i stadijum bolesti) 20 .…”

Section: Diskusijaunclassified