Prognostic factors for outcomes of idiopathic sudden sensorineural hearing loss: protocol for the SeaSHeL national prospective cohort study

Mandavia, Rishi; Hannink, Gerjon; Ahmed, Muhammad Nayeem; Premakumar, Y; Chu, Timothy Shun Man; Blackshaw, Helen; Ferdous, Tanjinah; Mehta, Nishchay; Manjaly, Joseph; Khan, Maha; Schilder, Anne G. M.

doi:10.1136/bmjopen-2020-038552

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…Owing to the fact that the disease process of SSNHL remains poorly understood it remains a topic undergoing extensive collaborative research within the otolaryngology community. The SeaSHeL National Prospective Cohort Study, 6 supported by INTEGRATE, the UK ENT Trainee Research Network and the National Institute for Health Research Clinical Research Network, is an on-going collaborative project which aims to establish a standardised patient pathway for those presented…”

Section: Case Reportmentioning

confidence: 99%

Catastrophic bilateral sudden sensorineural hearing loss following COVID-19

et al. 2021

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Since December 2019, when it was first detected in Wuhan, the SARS-CoV-2 (COVID-19) has spread across the globe. The pandemic has had an unprecedented impact on the global population with >110 million confirmed cases and 2.5 million deaths. The most common initial symptoms of COVID-19 infection are cough, dyspnoea, fever, malaise and anosmia. Severe clinical manifestations include respiratory compromise, pneumonia, organ failure and death. There have been many other less common symptoms as a result of COVID-19 described in the literature, including significant rates of olfactory dysfunction. However, we believe there has been only one other previously documented cases of bilateral hearing loss.Sudden sensorineural hearing loss is a relatively common presentation seen by otolaryngologists. It is defined as rapid hearing loss, ≥30 dB occurring over 3 consecutive days in three contiguous sound frequencies. The exact pathological process is yet to be fully characterised, though it is most commonly unilateral and commonly develops shortly following viral infection. Treatment typically consists of glucocorticoid steroids administered orally, via intratympanic injection or a combination of both routes though there are currently no standardised management of these patients.Bilateral sudden sensorineural hearing loss (SSNHL) is rare, accounting for <2% of all cases. We describe a case of bilateral SSNHL in a 68-year-old patient who presented with profound hearing loss shortly after symptomatic infection with COVID-19, which at the time of publication is the first such case reported in the literature.

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Section: Case Reportmentioning

confidence: 99%