Prognostic factors, clinical course, and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for acute respiratory failure

Afessa, Bekele; Morales, Ian J.; Scanlon, Paul D.; Peters, Steve G.

doi:10.1097/00003246-200207000-00035

Cited by 124 publications

(123 citation statements)

References 28 publications

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“…In this study the overall mortality rate for patients with AECOPD requiring ICU admission was 12% which is slightly lower than the rates reported in other studies which ranged from 15% to 24%. 9,10 Our study demonstrated that patients with AE-COPD have lower survival rates if they have low mean A high blood urea nitrogen was also associated with higher mortality in our study. BUN is a component of the CURB-65 which predicts the severity of pneumonia and the BAP-65 which predicts poor outcomes in AECOPD.…”

Section: Chok Limsuwat Etal Factors Affecting Mortality In Aecopd DIsupporting

confidence: 53%

“…[4][5][6][7][8] This rate is much higher in the intensive care unit (ICU) setting and approaches 30% in patients older than 65. 9,10 Comorbidity appears to increase the mortality with AECOPD, and recent studies have focused on clinical parameters which predict inpatient and 30-day mortality following AECOPD. [11][12][13][14] These studies used models with PaCO2, oxygen saturation 15 , BMI 16,17 , age 16,18,19 , and comorbidities to predict in-hospital mortality during AECOPD.…”

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confidence: 99%

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Factors affecting mortality in patients with COPD exacerbations requiring ICU admission

Limsuwat¹,

Nantsupawat²,

Umyarova³

et al. 2013

SWRCCC

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Section: Chok Limsuwat Etal Factors Affecting Mortality In Aecopd DIsupporting

confidence: 53%

mentioning

confidence: 99%

Factors affecting mortality in patients with COPD exacerbations requiring ICU admission

Limsuwat¹,

Nantsupawat²,

Umyarova³

et al. 2013

SWRCCC

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“…Despite widely analyzed pathophysiological processes and new treatment methods in laboratory and clinical research, less data are available on the causes of death, short-and long-term outcomes of critically ill patients, and associated risk factors. Frequently, data on specific predictive criteria for single diseases have been identified (Benoit et al, 2003;Wunsch et al, 2008;Afessa et al, 2002;Arabi et al, 2004). But, little is known on the exact causes of death and the influence of general risk factors that may consistently complicate the course of critically ill patients regardless of the underlying disease (Estenssoro et al, 2002;Khouli et al, 2005Chang et al, 2006.…”

Section: Introductionmentioning

confidence: 99%

Clinical outcomes of patients admitted in intensive care units of Nigist Eleni Mohammed Memorial Hospital of Hosanna, Southern Ethiopia

Obsa¹,

Adem²,

Gete³

2017

Int. J. Med. Med. Sci.

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An intensive care unit is a special department of hospital or health care facility that provides intensive treatment medicine. Critically ill patients are admitted to the intensive care unit to reduce morbidity and mortality associated with acute illness, trauma or surgical procedures. This study aimed to assess clinical outcomes of patients admitted in intensive care units of Nigist Eleni Mohammed Memorial Hospital of Hosanna from January 2015 to January 2016. Institutional based cross sectional study design was conducted. All the study participants admitted to intensive care unit were included. Regular supervision and follow up was made. Data was entered into Epi info version 7 by investigators and was transported to SPSS version 20 for analysis. Bivariate and multivariate analysis was used to identify factors associated with patient's outcome. A total of 280 clients were enrolled into the study of which 46.42% died. About 26% of patients were found in the age group of 20 to 24 years and majority of them were male (58.2%). Patient with head injury is about six times more likely to die in the intensive care unit than patients with small bowel obstruction (AOR 6.620 (95% CI ((468-93.584). There were poor outcomes of patients admitted to intensive care unit so that it was strongly recommended to improve quality of care.Key word: Ethiopia, intensive care unit, cause of death, hospital discharge.

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“…The prognosis for such patients has been related to multiple factors, including pulmonary function test results, blood gas analysis results, degree of pulmonary hypertension, age, nutritional status, need for ventilatory support, and APACHE II score at ICU admission. (6,9,(16)(17)(18)(19) The reintegration of such patients into society, in terms of their ability to maintain adequate social interaction or perform their activities satisfactorily, has yet to be thoroughly investigated. (12)(13)(14)(15) There are few data regarding the need for hospital readmissions, the degree of dependence, the ability to remain self-sufficient, and the ability to resume work activities.…”

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confidence: 99%

Exacerbação aguda da DPOC: mortalidade e estado funcional dois anos após a alta da UTI

et al. 2011

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Objective: To assess ICU patients with COPD, in terms of in-hospital characteristics, two-year mortality and two-year functional status of survivors. Methods: A prospective cohort study involving patients with acute exacerbation of COPD admitted to the ICUs of two hospitals in the city of Porto Alegre, Brazil, between July of 2005 and July of 2006. At two years after discharge, survivors were interviewed by telephone in order to determine Karnofsky scores and scores on a scale regarding activities of daily living (ADL). Results: The sample comprised 231 patients. In-hospital mortality was 37.7%, and two-year post-discharge mortality was 30.3%. Of the 74 survivors, 66 were interviewed (89%). The mean age at ICU admission was 74 ± 10 years, and the mean Acute Physiology and Chronic Health Evaluation II score was 18 ± 7. Two or more comorbidities were present in 87.8% of the patients. Of the 66 interviewees, 57 (86.3%) lived at home, 58 (87.8%) were self-sufficient, 12 (18.1%) required oxygen therapy, and 4 (6.1%) still required ventilatory support. There was a significant reduction in the quality of life and autonomy of the survivors, as evidenced by the Karnofsky scores (85 ± 9 vs. 79 ± 11, p = 0.03) and ADL scale scores (29 ± 5 vs. 25 ± 7; p = 0.01), respectively. Conclusions: In this patient sample, two-year mortality was quite high. Although there was a noticeable reduction in the functional status of the survivors, they remained self-sufficient.Keywords: Pulmonary disease, chronic obstructive/mortality; Quality of life; Intensive care units. ResumoObjetivo: Determinar a taxa de mortalidade de pacientes com DPOC e avaliar o estado funcional dos sobreviventes dois anos após a alta da UTI. Métodos: Estudo de coorte prospectiva realizada nas UTIs de dois hospitais na cidade de Porto Alegre (RS) com pacientes com exacerbação aguda de DPOC e internados em UTI entre julho de 2005 e julho de 2006. Dois anos após a alta, os sobreviventes foram entrevistados via telefone. Os dados obtidos foram utilizados na determinação dos escores da escala de Karnofsky e de uma escala de atividades de vida diária (AVD). Resultados: Foram incluídos 231 pacientes. A mortalidade hospitalar foi de 37,7% e a mortalidade extra-hospitalar foi de 30,3%. Dos 74 sobreviventes, foram entrevistados 66 (89%). A média de idade dos pacientes no momento da internação na UTI era de 74 ± 10 anos e a do escore Acute Physiology and Chronic Health Evaluation II era de 18 ± 7. Tinham duas ou mais comorbidades 87,8% dos pacientes. Dos 66 entrevistados, 57 (86,3%) viviam em suas casas, 58 (87,8%) eram capazes de realizar seu autocuidado, 12 (18,1%) utilizavam oxigenoterapia, e 4 (6,1%) necessitavam suporte ventilatório. Houve uma significante redução na qualidade de vida e na autonomia, segundo os escores da escala de Karnofsky (85 ± 9 vs. 79 ± 11; p = 0,03) e de AVD (29 ± 5 vs. 25 ± 7; p = 0,01), respectivamente. Conclusões: A mortalidade desta amostra de pacientes foi muito elevada nos primeiros dois anos. Embora houvesse evidente redução do esta...

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Prognostic factors, clinical course, and hospital outcome of patients with chronic obstructive pulmonary disease admitted to an intensive care unit for acute respiratory failure

Cited by 124 publications

References 28 publications

Factors affecting mortality in patients with COPD exacerbations requiring ICU admission

Factors affecting mortality in patients with COPD exacerbations requiring ICU admission

Clinical outcomes of patients admitted in intensive care units of Nigist Eleni Mohammed Memorial Hospital of Hosanna, Southern Ethiopia

Exacerbação aguda da DPOC: mortalidade e estado funcional dois anos após a alta da UTI

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