Prognostic factors after surgery for locally recurrent rectal cancer: An overview

Caricato, Marco; Borzomati, Domenico; Ausania, Fabio; Valeri, Sergio; Rosignoli, Alessandro; Coppola, Roberto

doi:10.1016/j.ejso.2005.11.001

Cited by 67 publications

(46 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These patients experienced a significantly better survival compared to patients who underwent a non-radical resection for their recurrence. As has been shown previously, radical resection of locally recurrent disease can achieve longterm survival [4,[13][14][15]24] and should, therefore, be aimed at, even if extended resection (e.g. abdominosacral resection or exenteration) [16,25,26] or flap-reconstruction [27] is required.…”

Section: Treatment Of Patients With Isolated Recurrent Diseasementioning

confidence: 99%

Management of recurrent rectal cancer: A population based study in greater Amsterdam

Bakx¹,

Visser²,

Josso³

et al. 2008

WJG

View full text Add to dashboard Cite

show abstract

Section: Treatment Of Patients With Isolated Recurrent Diseasementioning

confidence: 99%

Management of recurrent rectal cancer: A population based study in greater Amsterdam

Bakx¹,

Visser²,

Josso³

et al. 2008

WJG

View full text Add to dashboard Cite

show abstract

“…21 In our study, the risk of developing a PH by 2 years after surgery was 48%, higher than rates reported in the literature which range from 2.3% to 33%. 2,810,12,22 The higher rate of PH in our cohort likely relates to the use of radiographic diagnosis. Most studies use clinical definitions for PH, based upon the finding of protrusion in the vicinity of the stoma on physical exam, but methods for detection vary greatly, i.e., supine vs upright, with or without Valsalva maneuvers, self-reported vs documented by the examining surgeon.…”

Section: Discussionmentioning

confidence: 99%

1759 Risk Factors for the Development of Parastomal Hernia After Radical Cystectomy

et al. 2013

View full text Add to dashboard Cite

Purpose-Parastomal hernia (PH) is a frequent complication from stoma formation after radical cystectomy (RC). We sought to determine the prevalence and risk factors for developing PH following RC.Material and Methods-Retrospective study of 433 consecutive patients who underwent open RC and ileal conduit between 2006-2010. Postoperative cross-sectional imaging studies performed for routine oncologic follow-up (n=1736) were evaluated for PH, defined as radiographic evidence of protrusion of abdominal contents through the abdominal wall defect created by forming the stoma. Univariable and multivariable Cox regression analyses were used to determine clinical and surgical factors associated with PH.Results-Complete data were available for 386 patients with radiographic PH occurring in 136. The risk of developing a PH was 27% (95% CI 22-33%) and 48% (95% CI 42-55%) at 1 and 2 years. Clinical diagnosis of PH was documented in 93 patients and 37 were symptomatic. Of 16 patients with clinical PH referred for repair, 8 had surgery. On multivariable analysis, female gender (HR=2.25, 95%CI 1.58-3.21; p<0.0001), higher BMI (HR=1.08 per unit increase 95%CI 1.05-1.12; p<0.0001), and lower preoperative albumin (HR=0.43 per g/dl, 95%CI 0.25-0.75; p=0.003) were significantly associated with PH.Conclusions-The overall risk of radiographic evidence of PH approached 50% at 2 years. Female gender, higher BMI, and lower preoperative albumin were most associated with developing PH. Identifying those at greatest risk may allow for prospective surgical maneuvers at the time of initial surgery, such as placement of prophylactic mesh in selected patients, to prevent the occurrence of PH.

show abstract

“…Hazard Ratio (95% CI) P Em que pese à alta morbidade da exenteração pélvica, essa é a única oportunidade de controle da doença em longo prazo, haja vista que os demais tratamentos têm apresentado resultados desalentadores (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19).…”

Section: Tabela 7 -Análise Univariada De Fatores Prognósticosunclassified

“…Estima-se que entre 6 e 10% de todas as neoplasias retais se encontrem no estádio T4 no momento de seu diagnóstico (1)(2)(3). Por outro lado, as recidivas pélvicas após cirurgia potencialmente curativa têm variado de 4 a 50% (4)(5)(6)(7)(8). Somente a ressecção cirúrgica completa (R0) e em monobloco, interessando tanto a neoplasia quanto os órgãos adjacentes comprometidos, pode oferecer real possibilidade de controle da doença em longo prazo nessa situação clínica (1,2,4,(7)(8)(9)(10).…”

Section: Introductionunclassified

See 1 more Smart Citation

A exenteração pélvica para o câncer de reto: avaliação dos fatores prognósticos de sobrevida em 27 pacientes operados

Costa

Teixeira

Lupinacci

2008

Rev bras. colo-proctol.

View full text Add to dashboard Cite

INTRODUÇÃOO câncer de reto localmente avançado (T4) bem como a recidiva pélvica isolada representam situações clínicas desafiadoras na prática clínica diária. Ambas as condições condenam o doente a um sofrimento atroz e duradouro, comprometendo seriamente tanto sua sobrevida em longo prazo quanto sua própria qualidade de vida. Apresentam freqüências variáveis nas diferentes séries descritas. Estima-se que entre 6 e 10% de todas as neoplasias retais se encontrem no estádio T4 no momento de seu diagnóstico (1-3). Por

show abstract

Prognostic factors after surgery for locally recurrent rectal cancer: An overview

Cited by 67 publications

References 37 publications

Management of recurrent rectal cancer: A population based study in greater Amsterdam

Management of recurrent rectal cancer: A population based study in greater Amsterdam

1759 Risk Factors for the Development of Parastomal Hernia After Radical Cystectomy

A exenteração pélvica para o câncer de reto: avaliação dos fatores prognósticos de sobrevida em 27 pacientes operados

Contact Info

Product

Resources

About