Prognosis of facial growth in patients with unilateral complete clefts of the lip, alveolus and palate

Scheuer, Hanna A; Höltje, W. J.; Hasund, A; Pfeifer, G

doi:10.1054/jcms.2001.0227

Cited by 19 publications

(22 citation statements)

References 7 publications

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“…There was only one comparative study regarding the facial morphology of 2 groups of complete unilateral cleft lip and palate Brazilian children 12 . The findings of the present study showed that patients undergoing cleft repair surgery during childhood have a jaw development decreased compared to patients without cleft, corroborating other studies conducted in children and adults 1,[14][15][16][17][18][19][20][21][22] . Regarding the interaction age x cleft, the results were similar to those found by Gomide et al 16 who observed that retrusion of the maxilla is common feature of Brazilian individuals with cleft lip and palate in both genders, becoming more noticeable with advancing age in the pre and post-puberty [19][20][21] .…”

Section: Discussionsupporting

confidence: 92%

See 1 more Smart Citation

Craniofacial features of operated unilateral complete cleft lip and palate children: a case control study

Romanini

Vedovello

Raitz

et al. 2014

RGO, Rev. Gaúch. Odontol.

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Objective RESUMO ObjetivoComparar o crescimento ântero-posterior da maxila e da mandíbula entre pacientes com fissura unilateral completa de lábio e palato reparada e pacientes que não apresentavam nenhuma alteração craniofacial. MétodosForam selecionadas 46 telerradiografias cefalométricas em norma lateral de pacientes com fissura unilateral completa de lábio e palato que foram submetidos às cirurgias primárias de correção durante a infância (grupo de estudo). A amostra do grupo controle foi composta por 46 telerradiografias cefalométricas em norma lateral de pacientes sem nenhuma alteração craniofacial e que apresentavam valores para os ângulos SNA e SNB dentro dos valores pré-estabelecidos de normalidade. O gênero e as faixas etárias entre 6 e 9 anos dos pacientes foram pareados e comparados em ambos os grupos. A comparação entre os dois grupos foi realizada por meio dos ângulos SNA, SNB e ANB. Aplicouse a análise de variância (ANOVA), considerando-se o nível de significância de 5%. ResultadosObservou-se diferença significativa entre os grupos de pacientes com fissura reparada e controle (p<0,0001), ou seja, o grupo com fissura reparada apresentou menor média de SNA e SNB em todas as idades. Para o ângulo ANB, o grupo com fissura reparada apresentou maior média em todas as faixas etárias (p<0,05). ConclusãoPode-se concluir que o grupo de pacientes com fissura unilateral completa de lábio e palato reparada nas faixas etárias estudadas e em ambos os gêneros apresentaram maxila e mandíbula retruídas em uma relação esquelética de Classe II em relação ao grupo controle.

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Section: Discussionsupporting

confidence: 92%

“…This finding is consistent with the findings of Zemann et al 23 who observed the same growth pattern in patients with 6 years of age. However, some authors 16,18,24 have found a Class I skeletal relationship in various age groups and others 1,8,[14][15][16]18,[20][21]24 have found a Class III skeletal pattern post-pubertal growth.…”

Section: Collaboratorsmentioning

confidence: 99%

Craniofacial features of operated unilateral complete cleft lip and palate children: a case control study

Romanini

Vedovello

Raitz

et al. 2014

RGO, Rev. Gaúch. Odontol.

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“…Traditionally, the determination of the Goslon score or orthodontic measurements of occlusal cast models, and/or cephalometric studies have been used for such evaluations (Atack, 1997a,b;Lukash et al, 1998;Scheuer et al, 2001;DiBiase et al, 2002). However, multiple radiological examinations of children may add unnecessary exposure to radiation (Meazzini et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

Orthodontic characteristics of maxillary arch deficiency in 5-year-old patients undergoing unilateral cleft lip and palate repair with and without early gingivoplasty

Wojtaszek‐Słomińska

Renkielska

Dobke

et al. 2010

Journal of Cranio-Maxillofacial Surgery

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“…Here, we present such a method; combining traditional size measurements with geometric morphometrics adapted from a Xenopus study 12 and a wealth of studies analyzing human facial form [13][14][15] . The goal of this protocol is to allow researchers to quantify facial size and shapes to distinguish between different orofacial phenotypes during normal and abnormal development.…”

Section: Introductionmentioning

confidence: 99%

“…The combination of facial measurements and geometric morphometrics that we present here allows for a more comprehensive statistical analysis of both size and shape of the orofacial region than current protocols which largely utilize only one or the other [15][16][17][18] . Further, we present a simple way to assess both the medial and lateral planes of the face without requiring sophisticated three-dimensional imaging equipment used in current studies 13,19 .…”

Section: Introductionmentioning

confidence: 99%

Quantification of Orofacial Phenotypes in <em>Xenopus</em>

Kennedy

Dickinson

2014

JoVE

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Xenopus has become an important tool for dissecting the mechanisms governing craniofacial development and defects. A method to quantify orofacial development will allow for more rigorous analysis of orofacial phenotypes upon abrogation with substances that can genetically or molecularly manipulate gene expression or protein function. Using two dimensional images of the embryonic heads, traditional size dimensionssuch as orofacial width, height and area-are measured. In addition, a roundness measure of the embryonic mouth opening is used to describe the shape of the mouth. Geometric morphometrics of these two dimensional images is also performed to provide a more sophisticated view of changes in the shape of the orofacial region. Landmarks are assigned to specific points in the orofacial region and coordinates are created. A principle component analysis is used to reduce landmark coordinates to principle components that then discriminate the treatment groups. These results are displayed as a scatter plot in which individuals with similar orofacial shapes cluster together. It is also useful to perform a discriminant function analysis, which statistically compares the positions of the landmarks between two treatment groups. This analysis is displayed on a transformation grid where changes in landmark position are viewed as vectors. A grid is superimposed on these vectors so that a warping pattern is displayed to show where significant landmark positions have changed. Shape changes in the discriminant function analysis are based on a statistical measure, and therefore can be evaluated by a p-value. This analysis is simple and accessible, requiring only a stereoscope and freeware software, and thus will be a valuable research and teaching resource. Video LinkThe video component of this article can be found at

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Prognosis of facial growth in patients with unilateral complete clefts of the lip, alveolus and palate

Cited by 19 publications

References 7 publications

Craniofacial features of operated unilateral complete cleft lip and palate children: a case control study

Craniofacial features of operated unilateral complete cleft lip and palate children: a case control study

Orthodontic characteristics of maxillary arch deficiency in 5-year-old patients undergoing unilateral cleft lip and palate repair with and without early gingivoplasty

Quantification of Orofacial Phenotypes in <em>Xenopus</em>

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