Prognosis of Diabetic Patients Undergoing Coronary Artery Bypass Surgery Compared With Nondiabetics: A Systematic Review and Meta–analysis

Zhang, Xuena; Wu, Zhiguo; Peng, Xiaoxia; Wu, Anshi; Yue, Yun; Martin, Janet; Cheng, Davy

doi:10.1053/j.jvca.2010.09.021

Cited by 26 publications

(20 citation statements)

References 84 publications

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“…Кардиология Cardiology по сравнению с больными без СД [31,32]. В то же время во многих недавних исследованиях такой взаимосвязи проследить не удалось [33][34][35][36].…”

Section: сахарный диабет Diabetes Mellitus 474unclassified

Myocardial revascularization in patients with coronary heart disease and type 2 diabetes

Безденежных

Sumin

2016

Diabetes mellitus

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The review discusses myocardial revascularization in patients with coronary heart disease and type 2 diabetes. The data presented include findings from recent research and international and national recommendations and provides evidence on the advantages of coronary artery bypass surgery over percutaneous coronary intervention for patients with diabetes mellitus, stable coronary artery disease and multiple coronary artery lesions. Type 2 diabetes remains a significant predictor of adverse long-term outcomes of coronary artery bypass surgery. Therefore, we review studies showing that different strategies of coronary revascularization and preoperative preparation can affect the results of coronary intervention in patients with diabetes.

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Section: сахарный диабет Diabetes Mellitus 474unclassified

Myocardial revascularization in patients with coronary heart disease and type 2 diabetes

Безденежных

Sumin

2016

Diabetes mellitus

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“…Compared with patients without DM, early and long-term morbidity and mortality are higher in patients with DM after CABG, with increased risk of postoperative complications (Table 1). A recent meta-analysis of more than 100,000 patients showed that all-cause mortality is 1.6 to 1.8-fold greater in patients with DM at all times after CABG from 1 month to 10 years[12]. As such the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI-2D) trial tested the hypothesis that in DM patients and stable coronary disease, prompt revascularization, CABG or PCI, would reduce long-term rates of death and cardiovascular events as compared with medical therapy alone.…”

Section: Revascularization Versus Medical Therapymentioning

confidence: 99%

Role of CABG in the management of obstructive coronary arterial disease in patients with diabetes mellitus

Aronson

Edelman

2012

Current Opinion in Pharmacology

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Multiple studies have shown that diabetes mellitus (DM) can affect the efficacy of revascularization therapies and subsequent clinical outcomes. Selection of the appropriate myocardial revascularization strategy is critically important in the setting of multivessel coronary disease. Optimal medical therapy is an appropriate first-line strategy in patients with DM and mild symptoms. When medical therapy does not adequately control symptoms, revascularization with either PCI or CABG may be used. In patients with treated DM, moderate to severe symptoms and complex multivessel coronary disease, coronary artery bypass graft surgery provides better survival, fewer recurrent infarctions and greater freedom from re-intervention. Decisions regarding revascularization in patients with DM must take into account multiple factors and as such require a multidisciplinary team approach (‘heart team’).

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“…The morbitity and mortality levels of diabetic patients increased by 5-10 fold in post operation stage [2].…”

Section: Introductionmentioning

confidence: 99%

Preoperative Hba1c level in prediction of short-term morbidity and mortality outcomes following coronary artery bypass grafting surgery

Arslan¹,

Memetoğlu²,

Kutlu³

et al. 2015

RusOMJ

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Abstract:Objective -This study was conducted to determine whether HbA1c is a predictor of short term mortality and morbidity after coronary artery bypass graft operation. Methods -The coronary artery bypass graft operation was performed on the patients between January 2009 and January 2013. Each patient's medical record was retrospectively reviewed. The patients who were included in the study were evaluated in groups of 60. One group was comprised of nondiabetic patients, whose HbA1c level is below 6% (the control group 0), the other included diabetic patients with the HbA1c level is between 6-6.9% (the group 1) and the last group, group 2, included those patients with HbA1c level is equal or greater than 7%. Pre, peri and post operation data was compared. The deaths that occured in the first 30 days were evaluated as mortality and complications as morbitity. Results -While mortality was not observed in the control group, one incident was observed in group 1 and 5 in group 2, which corresponds to 1.7% and 8.3% respectively. The mortality ratio in the group with patients whose HbA1c was greater or equal to 7% found statistically significant compared to the control group (P=0.02). The following parameters were observed in group 2 and were found statistically significant: the need for dialisis (25%, P<0.01), atrial fibrillation (33%, P=0.01), revision due to bleeding (10%, P=0.18), cerebrovascular event (16,7%, P=0.01), duration of mechanic ventilation (19.5±21.6, P=0.06), duration of hospital stay (approximately 9.91±5.35 days, P=0.01), infection in scar (53%, P<0.01), mediastenit (11%, P=0.01) and urinary tract infection (10%, P=0.01) Conclusion -We concluded that in those diabetic patients that elective coronart artery bypass graft is applied, highly reactive HbA1c levels (HbA1c ≥7), may indicate morbitity in the early stages of post operation.

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Prognosis of Diabetic Patients Undergoing Coronary Artery Bypass Surgery Compared With Nondiabetics: A Systematic Review and Meta–analysis

Cited by 26 publications

References 84 publications

Myocardial revascularization in patients with coronary heart disease and type 2 diabetes

Myocardial revascularization in patients with coronary heart disease and type 2 diabetes

Role of CABG in the management of obstructive coronary arterial disease in patients with diabetes mellitus

Preoperative Hba1c level in prediction of short-term morbidity and mortality outcomes following coronary artery bypass grafting surgery

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