Prognosis of activities of daily living function in hospitalized patients with nursing and healthcare‐associated pneumonia due to COVID‐19

Miyashita, Naoyuki; Nakamori, Yasushi; Ogata, Makoto; Fukuda, N.; Yamura, Akihisa

doi:10.1111/irv.13045

Cited by 3 publications

(1 citation statement)

References 19 publications

(46 reference statements)

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“…In countries with an aging population or many older people, physicians should emphasize the function of activities of daily living (ADL) as a prognostic assessment of pneumonia, not just mortality [ 8 ]. Numerous studies have revealed that the diseases of poor functional status, multiple comorbidities, frailness, dysphagia, and malnutrition are highly prevalent in geriatric pneumonia and are related to adverse outcomes [ 9 – 12 ].…”

Section: Introductionmentioning

confidence: 99%

The relationship between comprehensive geriatric assessment on the pneumonia prognosis of older adults: a cross-sectional study

Li,

Jiang,

Sun

et al. 2024

BMC Pulm Med

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Background The mortality of pneumonia in older adults surpasses that of other populations, especially with the prevalence of coronavirus disease 2019 (COVID-19). Under the influence of multiple factors, a series of geriatric syndromes brought on by age is one of the main reasons for the poor prognosis of pneumonia. This study attempts to analyze the impact of geriatric syndrome on the prognosis of pneumonia. Methods This is a prospective cross-sectional study. Patients over 65 years old with COVID-19 and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-negative community-acquired pneumonia (SN-CAP) were included in the research. General characteristics, laboratory tests, length of stay (LOS), and comprehensive geriatric assessment (CGA) were collected. Multivariate regression analysis to determine the independent predictors of the severity, mortality, and LOS of COVID-19. At the same time, the enrolled subjects were divided into three categories by clustering analysis of 10 CGA indicators, and their clinical characteristics and prognoses were analyzed. Results A total of 792 subjects were included in the study, including 204 subjects of SN-CAP (25.8%) and 588 subjects (74.2%) of COVID-19. There was no significant difference between non-severe COVID-19 and SN-CAP regarding mortality, LOS, and CGA (P > 0.05), while severe COVID-19 is significantly higher than both (P < 0.05). The Barthel Index used to assess the activities of daily living was an independent risk factor for the severity and mortality of COVID-19 and linearly correlated with the LOS (P < 0.05). The cluster analysis based on the CGA indicators divided the geriatric pneumonia patients into three groups: Cluster 1 (n = 276), named low ability group, with the worst CGA, laboratory tests, severity, mortality, and LOS; Cluster 3 (n = 228), called high ability group with the best above indicators; Cluster 2 (n = 288), named medium ability group, falls between the two. Conclusion The Barthel Index indicates that decreased activities of daily living are an independent risk factor for the severity, mortality, and LOS of geriatric COVID-19. Geriatric syndrome can help judge the prognosis of pneumonia in older adults.

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Section: Introductionmentioning

confidence: 99%

The relationship between comprehensive geriatric assessment on the pneumonia prognosis of older adults: a cross-sectional study

Li,

Jiang,

Sun

et al. 2024

BMC Pulm Med

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Nursing and healthcare-associated pneumonia due to SARS-CoV-2 Omicron variant

Miyashita,

Nakamori,

Ogata

et al. 2024

Respiratory Investigation

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Aspiration pneumonia after SARS-CoV-2 Omicron infection frequently induced physical functional decline in Japan

Miyashita,

Nakamori,

Ogata

et al. 2024

Journal of Medical Microbiology

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Introduction. Nursing and healthcare-associated pneumonia (NHCAP) mainly occurs in older people whose physical functions have declined, and it is the most common type of pneumonia in Japan, a super-ageing society. In older people who meet NHCAP criteria, respiratory tract infections are often accompanied by aspiration pneumonia. Gap statement. The SARS-CoV-2 Omicron variant frequently causes aspiration pneumonia and has induced a decline in physical function. Aim. To clarify functional outcomes at 1 year after hospital discharge in SARS-CoV-2 Omicron-related NHCAP cases. Methodology. We compared the functional outcomes between 259 patients with primary SARS-CoV-2 pneumonia and 223 patients with aspiration pneumonia. Results. Functional decline rates for calculating the Barthel index at the time of hospital discharge were higher in the aspiration pneumonia group than the primary SARS-CoV-2 pneumonia group [114 patients (51.6%) vs 70 patients (27.0%), P<0.0001]. Of 114 patients with aspiration pneumonia who had a decline in physical function at the time of hospital discharge, 91 (79.8%) still showed functional decline 1 year later. In contrast, 9.3% of patients had functional decline at 1 year after hospital discharge in the primary SARS-CoV-2 pneumonia group, which was significantly lower than in the aspiration pneumonia group. Conclusions. The Omicron variant showed decreased infectivity in the lungs and was less pathogenic compared with the Delta and former variants. However, physicians should recommend SARS-CoV-2 vaccination and non-pharmaceutical interventions, depending on the presence or absence of applicable criteria for NHCAP, even when the predominant strain is the Omicron variant.

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Prognosis of activities of daily living function in hospitalized patients with nursing and healthcare‐associated pneumonia due to COVID‐19

Cited by 3 publications

References 19 publications

The relationship between comprehensive geriatric assessment on the pneumonia prognosis of older adults: a cross-sectional study

The relationship between comprehensive geriatric assessment on the pneumonia prognosis of older adults: a cross-sectional study

Nursing and healthcare-associated pneumonia due to SARS-CoV-2 Omicron variant

Aspiration pneumonia after SARS-CoV-2 Omicron infection frequently induced physical functional decline in Japan

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