Prognosis in Infective Endocarditis

Vilacosta, Isidre; Blanco, Carmen Olmos; Cepeda, Cristina Sarriá; Díaz, Javier López; Durán, Carlos Ferrera; Balcones, David Vivas; Castellanos, L. Maroto; Calvar, José Alberto San Román

doi:10.1007/978-3-319-32432-6_8

Cited by 2 publications

(3 citation statements)

References 73 publications

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“… 11 , 32 , 33 The lower surgical rate in the original study, 11 when compared to ours (26.9 vs. 38.0%), suggests that surgery may have been contraindicated in high-risk patients. 34 …”

Section: Discussionmentioning

confidence: 99%

“…11,32,33 A taxa de cirurgia mais baixa no estudo original 11 em comparação com a nossa (26,9 vs. 38,0%) sugere que a cirurgia teria sido contraindicada em pacientes em alto risco. 34 O escore SHARPEN foi comparado ao ICC pela sua capacidade de predizer mortalidade hospitalar em estudos anteriores. 6,35,36 apesar da acurácia relativamente baixa do ICC para predição de mortalidade hospitalar, um escore >3 foi associado com mortalidade elevada durante a internação, exceto no grupo não operado.…”

Section: Discussionunclassified

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Desempenho do Escore SHARPEN e do Índice de Comorbidade de Charlson para Predição de Mortalidade durante a Internação Hospitalar e após a Alta na Endocardite Infecciosa

Alves,

Pivatto,

Filippini

et al. 2023

Arquivos Brasileiros De Cardiologia

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Section: Discussionunclassified

“… 11 , 32 , 33 The lower surgical rate in the original study, 11 when compared to ours (26.9 vs. 38.0%), suggests that surgery may have been contraindicated in high-risk patients. 34 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionunclassified

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Desempenho do Escore SHARPEN e do Índice de Comorbidade de Charlson para Predição de Mortalidade durante a Internação Hospitalar e após a Alta na Endocardite Infecciosa

Alves,

Pivatto,

Filippini

et al. 2023

Arquivos Brasileiros De Cardiologia

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Etiology, clinical characteristics, and outcome of infective endocarditis: 10-year experience from a tertiary care center in Pakistan

Ali

Qureshi

Ahmed

et al. 2022

Monaldi Arch Chest Dis

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This study was conducted to assess the clinical characteristics, causative agents, complications, and outcomes of infective endocarditis (IE) among patients presenting to our tertiary care center over the last decade. This retrospective cohort study included all adult patients admitted to the Aga Khan University Hospital with the diagnosis of IE over a ten-year period from 2010 to 2020. Outcomes variables included complications during hospitalization, surgical intervention, mortality, and length of stay. We identified a total of 305 cases out of which 176 (58%) were males and 129 (42%) were females. The mean age of the patients was 46.9±18.8 years. 95 (31%) had prosthetic valves in place. Staphylococcus aureus was isolated in 54 (39%) patients followed by coagulase-negative Staphylococcus in 23 (17%). Echocardiography revealed vegetations and abscesses in 236 (77%) and 4 (1%) patients, respectively. The most common valvular complication was mitral valve regurgitation found in 26 (9%) patients, followed by tricuspid valve regurgitation in 13 (4%) patients and aortic valve regurgitation in 11 (3%) patients. Furthermore, 81 (27%) patients suffered from heart failure and 66 (22%) from a stroke during hospitalization. The mean hospital length of stay was 10.4 ± 10.6 days. 64 (21%) patients required surgical repair and the overall mortality rate was 25%. Prosthetic valve endocarditis (OR = 3.74, 95% CI = 2.15-6.50, p<0.001), chronic kidney disease (OR = 2.51, 95% CI = 1.15-5.47, p=0.036), previous stroke (OR = 2.42, 95% CI = 1.18-4.96, p=0.026), and ischemic heart disease (OR = 3.04, 95% CI = 1.50-6.16, p=0.003) were significantly associated with an increased risk of mortality. In conclusion, our study provided valuable data on the clinical characteristics and outcomes of patients with IE in a developing country. S. aureus was the most common causative agent. Heart failure and stroke were the most common complications. The presence of prosthetic valves, history of chronic kidney disease, ischemic heart disease and previous stroke were associated with a significantly increased risk of mortality. Surgical management was not associated with improved outcomes.

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Prognosis in Infective Endocarditis

Cited by 2 publications

References 73 publications

Desempenho do Escore SHARPEN e do Índice de Comorbidade de Charlson para Predição de Mortalidade durante a Internação Hospitalar e após a Alta na Endocardite Infecciosa

Desempenho do Escore SHARPEN e do Índice de Comorbidade de Charlson para Predição de Mortalidade durante a Internação Hospitalar e após a Alta na Endocardite Infecciosa

Etiology, clinical characteristics, and outcome of infective endocarditis: 10-year experience from a tertiary care center in Pakistan

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