Prognosis in children with Crohn's disease

Sensorineural hearing loss as an extra-intestinal manifestation of ulcerative colitis in an adolescent girl with pyoderma gangrenosum

“…Common skin findings in inflammatory bowel disease include erythema nodosum and pyoderma gangrenosum. Pyoderma gangrenosum is an indolent chronic ulcer that may occur even when the intestinal disease is in remission [5]. In our patient pyoderma gangrenosum was seen at about the onset of the gastrointestinal symptoms without any predisposing factors such as trauma.…”

Paediatric Crohn's disease: a radiological review

“…Radio-isotope study shows abnormal activity in the terminal ileum (arrow) which is greater than the activity in the bone marrow in a patient with active Crohn's disease cur and are found in up to 24 % of patients [32]. Finger clubbing can occur in up to 30 % of children with localised small bowel disease, but this figure can double if there is diffuse small bowel involvement [11]. Aphthous ulceration and stomatitis have an incidence between 1 and 4 % [32], and can be a presenting complaint.…”

“…Occasionally the diagnosis may be made during operation for suspected appendicitis or for a complication such as fistula or obstruction [10]. Children may also present with retarded growth and delayed [11], and growth delay may precede clinical illness by months or years [12]. Failure to thrive is another clinical presentation in the young child.…”

“…Arthritis and arthralgia are described in up to 27 % of children [11] and the symptoms may be present for several years before the development of gastrointestinal features. Any joint can be involved, but the hip, knee and ankle are most commonly affected, and involvement predominantly tends to be monoarticular.…”

Renal calculus at presentation in a child with Crohn's disease

“…A few general studies of the complications of paediatric inflammatory bowel disease mention nephrolithiasis, and from these the incidence would appear to be lower than in adults at 3-5% [3,4,5]. In one study, only calculi that passed spontaneously were mentioned [4].…”