1985
DOI: 10.1097/00000658-198512000-00004
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Prognosis in Acute Organ-System Failure

Abstract: This prospective study describes the current prognosis of patients in acute Organ System Failure (OSF). Objective definitions were developed for five OSFs, and then 5677 ICU admissions from 13 hospitals were monitored. The number and duration of OSF were linked to outcome at hospital discharge for each of the 2719 ICU patients (48%) who developed OSF. For all medical and most surgical admissions, a single OSF lasting more than 1 day resulted in a mortality rate approaching 40%. Among both medical and surgical … Show more

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Cited by 971 publications
(387 citation statements)
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“…12 The presence of organ system failure (OSF) during each unit admission was noted using the definitions developed by Knaus et al 12 FIGURE 1 A schematic representing the functions of the "audit cycle" which involves administrative responsibility, data collection. management, and the analysis procedure (primary analysis with report generation and secondary analysis with revisions to policy and procedure).…”
Section: Diagnoses Complications and Severity Of Illnessmentioning
confidence: 99%
“…12 The presence of organ system failure (OSF) during each unit admission was noted using the definitions developed by Knaus et al 12 FIGURE 1 A schematic representing the functions of the "audit cycle" which involves administrative responsibility, data collection. management, and the analysis procedure (primary analysis with report generation and secondary analysis with revisions to policy and procedure).…”
Section: Diagnoses Complications and Severity Of Illnessmentioning
confidence: 99%
“…The sequential/sepsi organ failure assessment score (SOFA score), showed a score = 7 (predominantly mild renal and bilirubin modifications). The APACHE II (''acute physiology and chronic health evaluation II''), another important ICU scoring system [5] showed 16 points with a calculated predicted death rate of 23.5%.…”
Section: Dr G Pepementioning
confidence: 99%
“…The period between extubation and diagnosis of hypercapnic respiratory insufficiency was 20 14 h. In both groups, all patients with a GCS score of #8, inconsistent with NIPSV use, and requiring immediate endotracheal ventilation were excluded. Haemodynamic instability with a sustained systolic arterial blood pressure of <80 mmHg or failure of more than two organs [17] were also exclusion criteria.…”
Section: Subjectsmentioning
confidence: 99%