Progestin-only contraceptives: effects on weight

Lopez, Laureen M; Edelman, Alison; Chen-Mok, Mario; Helmerhorst, Frans M.

doi:10.1002/14651858.cd008815

Cited by 40 publications

(57 citation statements)

References 28 publications

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“…There was a wide range of weight change in both groups; this was similar to previous reports by other studies . The mean change in weight in this study was slightly higher than reports from many studies . This may be due to the fact that all the participants in this study were black.…”

Section: Discussionsupporting

confidence: 89%

“…A study on the incidence of major weight gain reported a 50% higher incidence among black women than white women aged 30–55 years . There was a wide range of weight change in both groups; this was similar to previous reports by other studies . The mean change in weight in this study was slightly higher than reports from many studies .…”

Section: Discussionsupporting

confidence: 87%

“…This may be due to the fact that all the participants in this study were black. Most studies reported a weight gain of less than 2 kg for progesterone‐only contraceptives . However, findings are comparable to a mean weight gain of 4.8 kg reported by Sule et al .…”

Section: Discussionsupporting

confidence: 70%

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Comparison of weight gain between levonorgestrel and etonogestrel implants after 12 months of insertion

Okunola

Bola-Oyebamiji

Sowemimo

2019

Intl J Gynecology & Obste

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Objective To compare weight gain between women using etonogestrel implants and those using levonorgestrel implants 12 months after insertion. Methods A multicenter prospective cohort study was performed on women recruited from family planning clinics between July 2016 and August 2017. The main study outcome was mean weight gain after 12 months of insertion of the implants. Results The present study included 150 women (age range 18–45 years) using levonorgestrel implants and 167 women using etonogestrel implants. The women recruited had been using implants for less than 6 months; implants had been inserted 6–12 months after their last pregnancy. Participants were followed up until 12 months after insertion through telephone conversations. Baseline parameters were obtained from the clinic records and weight was measured within 6 weeks of the 12‐month anniversary of insertion of the implants. Data were analyzed with SPSS version 23. Weight gain in the levonorgestrel group was significantly higher than in the etonogestrel group (3.16 ± 4.08 vs 0.77 ± 3.76, P = 0.013; relative risk 1.69, 95% confidence interval 1.46–1.96). There were no differences in the occurrence of menstrual irregularities and client satisfaction. Conclusion Women using levonorgestrel implants were more likely to gain weight compared to those using etonogestrel implants after 12 months of insertion.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionsupporting

confidence: 87%

See 1 more Smart Citation

Comparison of weight gain between levonorgestrel and etonogestrel implants after 12 months of insertion

Okunola

Bola-Oyebamiji

Sowemimo

2019

Intl J Gynecology & Obste

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“…Furthermore, despite considerable evidence from both animal and human studies of a metabolic stimulation by progesterone , direct evidence concerning the effects of progesterone‐only contraception is also mixed, with no effect on EE reported in the short term , but other authors showing an increase in BMR at 12 months follow‐up . A recent systemic review found little evidence for an effect of progesterone‐only contraceptive use on body weight . Curiously, of the studies that did report a body‐weight effect (two of 16 reviewed), both observed greater fat mass rather than fat‐free mass in hormonal contraceptive users, in apparent contrast to the potential anabolic action of progesterone.…”

Section: Disparity In Resting Compartments Of Energy Expenditurementioning

confidence: 99%

Gender‐specific considerations in physical activity, thermogenesis and fat oxidation: implications for obesity management

Isacco¹,

Miles-Chan

2018

Obesity Reviews

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With current 'one-size-fits-all' obesity prevention and management strategies proving largely ineffective, the focus has shifted towards a more tailored, individualized approach. However, investigation of the mechanisms underlying inter-individual variability in metabolic profile and response to intervention often yield conflicting results. Indeed, it is perhaps surprising that despite at least a century of recognition that sex hormones influence metabolism, firm conclusions regarding the effects of the menstrual cycle, hormonal contraception and menopause on many aspects of energy expenditure and substrate utilization remain to be drawn. In this review, we examine current evidence relating to gender-specific considerations in the promotion of physical activity, thermogenesis and fat oxidation for body-weight regulation, including the relationship between sex hormone status and non-exercise activity thermogenesisan energy expenditure compartment that is often overlooked in favour of traditional exercise/sport physical activities yet presents a viable target in the search for effective weight management.

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“…An important concern of women using hormonal contraception in general is the possibility of weight gain. Evidence about weight gain with oral or parenteral progestin‐only contraception is conflicting; however, the limited data generally indicate a stable body weight with an IUS [19,20]. The current study offered a chance to compare weight changes among women using an IUCD versus an IUS.…”

Section: Discussionmentioning

confidence: 93%

Five‐year follow‐up of two types of contraceptive device fitted during elective cesarean delivery

Elsedeek

2015

Intl J Gynecology & Obste

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Progestin-only contraceptives: effects on weight

Cited by 40 publications

References 28 publications

Comparison of weight gain between levonorgestrel and etonogestrel implants after 12 months of insertion

Comparison of weight gain between levonorgestrel and etonogestrel implants after 12 months of insertion

Gender‐specific considerations in physical activity, thermogenesis and fat oxidation: implications for obesity management

Five‐year follow‐up of two types of contraceptive device fitted during elective cesarean delivery

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