Progestin Contraceptives

Schnare, S

doi:10.1016/s1526-9523(02)00230-1

Cited by 5 publications

(3 citation statements)

References 37 publications

(56 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This method is extremely effective since all that's required of a woman is to return to her health care provider for a shot every three months. Benefits and side effects of Depo-Provera® are similar to those of progestin only pills [3] .…”

Section: Introductionmentioning

confidence: 91%

Contraceptive Methods: Cost/Effectiveness Ratio from a Customer’s Perspective in Palestine

Barham**¹,

Sweileh*²

2003

An-Najah University Journal for Research - A

View full text Add to dashboard Cite

The purpose of the study was to determine the clinical and economic impact of alternative contraceptive methods to be used by women in Palestine. Effectiveness of the various tested methods was obtained from literature survey. Direct medical costs (medical consultation and drug costs) per user per day of use associated with six modern contraceptive methods were modeled from the perspectives of the Palestinian customer. Cost data were drawn from community pharmacies price list dated August 2002. Cost-effectiveness analysis shows that the most cost-effective (C/E) methods were intrauterine device (IUD) and injectable Depo-Provera® while the least cost-effective methods were the progestin only and combined oral contraceptive pills. The pharmaco-economic analysis of the data shows that over one year of use per 1000 patients, the IUD method makes 35,000 USD of savings compared to progestin only pills (POP) and 19,000 USD of savings compared to combined oral contraceptive pills (COC). This pharmaco-economic evaluations of the available fertility modulating methods and devices should assist the Palestinian married women and health professionals in rational selection of contraceptive method. هدف هذه الدراسة هو تحديد التأثير الطبي والإقتصادي لطرق منع الحمل المختلفة التي تستعمل في فلسطين. فعالية الطرق المختلفة لمنع الحمل تم تحديدها بواسطة مراجعة النشرات العلمية والدراسات المسحية الموثقة والمنشورة. أما التكلفة الطبية المباشرة لطرق منع الحمل المختلفة (الإستشارة الطبية مضافاً اليها سعر الدواء) فقد تم حسابها لست (6) طرق محتلفة لمنع الحمل. لقد تم تحديد الأسعار والتكلفة الطبية بناءً على قوائم أسعار الأدوية المعتمدة في صيدليات المجتمع في فلسطين بتاريخ شهر أب 2002. ان التحليل (نسبة التكلفة/الفاعلية) قد أظهر أن اللوالب والحقن طويلة المفعول هي الأفضل للمستهلك الفلسطيني من حيث نسبة التكلفة/الفاعلية. في حين أن حبوب منع الحمل بأنواعها كانت الأسوء من حيث نسبة التكلفة/الفاعلية. ان الجدوى الأقتصادية لهذة الدراسة تشير الى أنه يمكن توفير 35000 دولار سنوياً اذا تم استعمال اللوالب بدل حبوب منع الحمل المحتوية على البروجيسترون ويمكن توفير 19000 دولار سنوياً اذا تم استعمال اللوالب بدل حبوب منع الحمل المحتوية على البروجيسترون والايستروجين. ان هذة الدراسة الصيدلانية الإقتصادية ستعمل على مساعدة المرأة الفلسطينية والعاملين في الحقل الطبي على اختيار أفضل طرق منع الحمل من حيث نسبة التكلفة/الفاعلية.

show abstract

Section: Introductionmentioning

confidence: 91%

Contraceptive Methods: Cost/Effectiveness Ratio from a Customer’s Perspective in Palestine

Barham**¹,

Sweileh*²

2003

An-Najah University Journal for Research - A

View full text Add to dashboard Cite

show abstract

“…Hence, a variety of synthetic progestogens are used in contraceptive formulations ( Table 1). The gonanes and estranes [4] are structural classifications for derivatives of 19-nortestosterone. All estranes require conversion into norethindrone for biological activity.…”

Section: Introductionmentioning

confidence: 99%

Progestogen only contraception and endometrial break through bleeding

Smith

Critchley

2005

Angiogenesis

View full text Add to dashboard Cite

Progestogen only contraceptives (POC) provide a safe and effective method of fertility regulation. Unfortunately, they are commonly associated with the problem of endometrial break through bleeding (BTB), often leading to discontinuation of use. An increase in endometrial vascular fragility has been demonstrated as an important mechanism that contributes to BTB but our understanding of the interaction between exogenous steroid use and endometrial vasculature remains incomplete. This review sets out to describe a number of commonly used POC, their effects on endometrial morphology and possible molecular and cellular mechanisms that may lead to unscheduled bleeding.

show abstract

“…Thus, progestins have many therapeutic uses among which oral contraception (OC) and hormone replacement therapy (HRT), alone or in combination with estrogen [2][3][4]. Several synthetic progestins are currently being used in HRT and OC, and the newer generations of progestins have improved receptor selectivity, higher potency, and fewer side effects.…”

Section: Introductionmentioning

confidence: 99%