Progesterone, Monoamines and Sexual Behavior

Meyerson, Bengt J.; Sietnieks, Anni

doi:10.1016/b978-0-08-026864-4.50028-1

Cited by 8 publications

(12 citation statements)

References 12 publications

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“…Overli et al 1999) that could directly or indirectly inhibit courtship behaviour (e.g. Meyerson & Malmnäs 1978;Morgan et al 1999). Serotonin is thought to have a stimulatory effect on ACTH (the adrenocorticotrophic hormone), which is considered to be the main factor for pituitary control of the interrenal release of cortisol (Winberg et al 1997), as well as a depressive effect on reproductive hormones including androgens (Sapolsky 1993).…”

Section: Discussionmentioning

confidence: 99%

The outcome of male–male encounters affects subsequent sound production during courtship in the cichlid fish Oreochromis mossambicus

Amorim

Almada

2005

Animal Behaviour

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Section: Discussionmentioning

confidence: 99%

The outcome of male–male encounters affects subsequent sound production during courtship in the cichlid fish Oreochromis mossambicus

Amorim

Almada

2005

Animal Behaviour

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“…of serotonin in inhibiting lordosis behavior has been suggested by several investigators (see Meyerson & Malmnas, 1978;Crowley & Zemlan, 1981). Treatment with serotonin agonists suppressed lordosis in estrogen-progesterone primed ovariectomized rats (Everitt et al, 1974;Zemlan et al, 1977;; conversely, serotonin antagonists facilitated lordosis behavior (Zemlan et al, 1973).…”

Section: Possible Participationmentioning

confidence: 97%

Forebrain lordosis inhibiting system and serotonin neuron in female rats: Effect of P-chloroamphetamine.

Yamanouchi¹,

Watanabe

Okada

et al. 1982

Endocrinol Japon

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Relationship between forebrain lordosis inhibiting system and serotonergic mechanism was examined in estradiol benzoate (EB) and progesterone (P)-primed ovariectomized rats. In order to remove the forebrain inhibition of lordosis response, anterior roof deafferentation (ARD) which interrupts the dorsal inputs to the POA coming down anterior to the anterior commissure or medial preoptic area lesions (POA-L) were made. All experimental females pretreated with EB and P showed high levels of lordotic activity. Soon after the behavioral tests, the animals were injected with 10 mg/kg p-chloroamphetamine (PCA) intraperitoneally and tested again 30 min later. PCA strongly suppressed female sexual behavior.Regardless of the presence of ARD or POA-L, no PCA injected females showed lordosis. From these results, it can be said that serotonin may not directly act on the forebrain lordosis inhibiting system.

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“…The protein synthesis in hibitor anisomycin, when given immediately before proges terone, inhibited the latter's lordosis-stimulating effect [17]. Extensive neuropharmacological studies have shown a relationship between the hormone-activated LR and monoaminergic activity [5,6,12,13]. A direct relationship be tween the progesterone action and monoaminergic mecha nisms has not yet been proven.…”

Section: Discussionmentioning

confidence: 99%

“…This effect was specific to progesterone, as no analogous effect was achieved by altered estrogen treat ment. A direct interaction between progesterone and seroto nergic mechanisms was suggested.The copulatory behavior in the ovariectomized rat acti vated by estrogen and progesterone is also inhibited by the monoamine precursors L-5-HTP and L-Dopa [ 13].In the present study we examined the question whether the enhancement of the LSD inhibitory effect by progeste rone may be extended to the effect of an endogenous in crease of 5-HT or catecholamines achieved by DL-5-HTP and L-Dopa. …”

mentioning

confidence: 95%

Enhancement by Progesterone of 5-Hydroxytryptophan Inhibition of the Copulatory Response in the Female Rat

Sietnieks¹,

Meyerson²

1982

Neuroendocrinology

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A study was made of the influence of different hormonal treatments used to induce copulatory behavior in ovariectomized female rats (lordosis behavior), on the effects of an endogenous increase of 5-HT or catecholamines achieved by DL-5-HTP and L-Dopa. The lordosis response (LR) has been shown to be inhibited by increased serotonergic and catecholaminergic neuronal activity. The 5-HT agonist lysergic acid diethylamide (LSD) has been found to inhibit the LR. This effect was recently shown to be enhanced by increasing doses of progesterone. In the present study it was demonstrated that the inhibitory effect of the 5-HT precursor 5-hydroxytryptophan was also potentiated by increased doses of progesterone. However, the effect of DL-5-HTP on spontaneous behaviors in an exploratory situation was not influenced by progesterone treatment. In contrast to the results with DL-5-HTP, progesterone had no modulating effects on the lordosis-inhibiting action of the catecholamine precursor levo-dopa. This selective effect on the influence of a progesterone-dependent response suggests a direct relationship between 5-HT mechanisms and the progesterone action involved in the LR. Possible mechanisms underlying the observed interactive effect of progesterone and serotonin on lordosis behavior, such as a progesterone-induced alteration of serotonergic transmission, are discussed.

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Progesterone, Monoamines and Sexual Behavior

Cited by 8 publications

References 12 publications

The outcome of male–male encounters affects subsequent sound production during courtship in the cichlid fish Oreochromis mossambicus

The outcome of male–male encounters affects subsequent sound production during courtship in the cichlid fish Oreochromis mossambicus

Forebrain lordosis inhibiting system and serotonin neuron in female rats: Effect of P-chloroamphetamine.

Enhancement by Progesterone of 5-Hydroxytryptophan Inhibition of the Copulatory Response in the Female Rat

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