Profiling to Probing: Atomic force microscopy to characterize nano-engineered implants

Gulati, Karan; Adachi, Taiji

doi:10.1016/j.actbio.2023.08.006

Cited by 11 publications

(5 citation statements)

References 211 publications

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“…Roughness values (Ra) were calculated by the software of the AFM and reported in nanometers [ 28 ]. Surface roughness analysis by AFM was chosen in this study due to its precise imaging quality and great ability to analyse, revealing vital details about topography, which affects osseointegration, stability, and biocompatibility for improved biomedical outcomes [ 29 , 30 ].…”

Section: Methodsmentioning

confidence: 99%

Evaluation of High-Performance Polyether Ether Ketone Polymer Treated with Piranha Solution and Epigallocatechin-3-Gallate Coating

Alsmael,

Al-Khafaji

2024

BioMed Research International

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Background. Dental implantation has become a standard procedure with high success rates, relying on achieving osseointegration between the implant surface and surrounding bone tissue. Polyether ether ketone (PEEK) is a promising alternative to traditional dental implant materials like titanium, but its osseointegration capabilities are limited due to its hydrophobic nature and reduced surface roughness. Objective. The aim of the study is to increase the surface roughness and hydrophilicity of PEEK by treating the surface with piranha solution and then coating the surface with epigallocatechin-3-gallate (EGCG) by electrospraying technique. Materials and Methods. The study includes four groups intended to investigate the effect of piranha treatment and EGCG coating: a control group of PEEK discs with no treatment (C), PEEK samples treated with piranha solution (P), a group of PEEK samples coated with EGCG (E), and a group of PEEK samples treated with piranha solution and coated with EGCG (PE). Surface roughness, wettability, and microhardness were assessed through statistical analysis. Results. Piranha treatment increased surface roughness, while EGCG coating moderated it, resulting in an intermediate roughness in the PE group. EGCG significantly improved wettability, as indicated by the reduced contact angle. Microhardness increased by about 20% in EGCG-coated groups compared to noncoated groups. Statistical analysis confirmed significant differences between groups in all tests. Conclusion. This study demonstrates the potential of EGCG coating to enhance the surface properties of PEEK as dental implants. The combined piranha and EGCG modification approach shows promise for improved osseointegration, although further vivo research is necessary. Surface modification techniques hold the key to optimizing biomaterial performance, bridging the gap between laboratory findings and clinical implementation in dental implantology.

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Section: Methodsmentioning

confidence: 99%

Evaluation of High-Performance Polyether Ether Ketone Polymer Treated with Piranha Solution and Epigallocatechin-3-Gallate Coating

Alsmael,

Al-Khafaji

2024

BioMed Research International

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“…A comprehensive understanding of the basic modes and advanced applications of AFM was presented by [262]. A paper performed by [263] further emphasized the application of AFM in characterizing nano-engineered implants. Another study provided by [264] used AFM in the measurements of nanoscale mechanical properties of cement pastes.…”

Section: Atomic Force Microscopy: Provides Nanoscale Surface Profilin...mentioning

confidence: 99%

Experimental Techniques for Testing the Properties of Construction Materials

Habib,

AL Houri,

Al-Toubat

et al. 2024

Preprint

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The field of construction materials is pivotal in developing sustainable and resilient infrastructure. This demands continuous research to understand the properties and behaviors of these materials under diverse conditions. Although advancements in material science and numerical modeling have been significant, experimental testing remains indispensable for a thorough comprehension of material characteristics, particularly under extreme stresses and environmental factors. This need has forced the development of a wide array of testing techniques, each designed to evaluate specific engineering properties, thus creating a complex and varied landscape of experimental methodologies. This study provides a comprehensive overview of both conventional and innovative experimental testing techniques used to characterize construction materials. It explores the related methodologies and identifies potential gaps in their application within the industry. The spectrum of testing covered includes mechanical, chemical, thermal, microstructural, durability, physical, rheological properties, and non-destructive testing methods. Mechanical tests assess strength, hardness, and fatigue, whereas chemical analyses utilize techniques such as spectroscopy and chromatography. Thermal properties are examined using thermogravimetric analysis, and microstructural characteristics are explored through advanced imaging techniques. Durability testing focuses on materials’ resistance to environmental challenges, while physical properties tests evaluate aspects like porosity and water absorption. Rheological and non-destructive tests further examine materials’ behavior and integrity without causing damage. By discussing these methodologies, the study sheds light on various approaches to material evaluation and aims to enhance the selection, application, and development of testing standards. This overview seeks to inform and inspire future research and innovation in the science of construction materials, contributing to the development of more resilient and sustainable construction practices.

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“…Utilizing a single instrument, namely atomic force microscopy (AFM), enables the simultaneous acquisition of nanomechanical and topographical data from nanostructured surfaces [1]. Using the same instrument for all surface analysis is not only efficient, but data are also calibrated parallel to each other in a comparable format and in the same environment using the same measuring probe.…”

Section: Introductionmentioning

confidence: 99%

Damage Behavior with Atomic Force Microscopy on Anti-Bacterial Nanostructure Arrays

Wood,

Bright,

Palms

et al. 2024

Nanomaterials

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The atomic force microscope is a versatile tool for assessing the topography, friction, and roughness of a broad spectrum of surfaces, encompassing anti-bacterial nanostructure arrays. Measuring and comparing all these values with one instrument allows clear comparisons of many nanomechanical reactions and anomalies. Increasing nano-Newton-level forces through the cantilever tip allows for the testing and measuring of failure points, damage behavior, and functionality under unfavorable conditions. Subjecting a grade 5 titanium alloy to hydrothermally etched nanostructures while applying elevated cantilever tip forces resulted in the observation of irreversible damage through atomic force microscopy. Despite the damage, a rough and non-uniform morphology remained that may still allow it to perform in its intended application as an anti-bacterial implant surface. Utilizing an atomic force microscope enables the evaluation of these surfaces before their biomedical application.

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Profiling to Probing: Atomic force microscopy to characterize nano-engineered implants

Cited by 11 publications

References 211 publications

Evaluation of High-Performance Polyether Ether Ketone Polymer Treated with Piranha Solution and Epigallocatechin-3-Gallate Coating

Evaluation of High-Performance Polyether Ether Ketone Polymer Treated with Piranha Solution and Epigallocatechin-3-Gallate Coating

Experimental Techniques for Testing the Properties of Construction Materials

Damage Behavior with Atomic Force Microscopy on Anti-Bacterial Nanostructure Arrays

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