Profiling of the microbiota of breast milk before and after feeding with an artificial nipple

Sano, Hiroto; Wakui, Anna; Kawachi, Miho; Maruyama, Shingo; Moriyama, Sachie; Mayumi, Nishikata; Washio, Jumpei; Abiko, Yoshihiro; Mayanagi, Gen; Sakashita, Reiko; Tanaka, Kaori; Takahashi, Nobuhiro; Sato, Takuichi

doi:10.1016/j.job.2022.09.004

Cited by 2 publications

(2 citation statements)

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“…Even breast milk expressed in a clean procedure contains bacteria. 17 The fact that E. coli, an indicator of food bacterial contamination, was not detected from breast milk samples suggests that the processes of expressing and storing breast milk in this study were appropriate. The three samples in which bacteria were detected even after pasteurization with the milmo ® contained milk clots.…”

Section: Discussionmentioning

confidence: 85%

“…Breast milk samples collected in this study contained varying degrees of bacteria. Even breast milk expressed in a clean procedure contains bacteria 17 . The fact that E. coli , an indicator of food bacterial contamination, was not detected from breast milk samples suggests that the processes of expressing and storing breast milk in this study were appropriate.…”

Section: Discussionmentioning

confidence: 94%

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Sterilization efficacy of a new water‐free breast milk pasteurizer

Chishiki

Nishiyama

Suzutani

et al. 2023

Pediatrics International

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BackgroundBreast milk, nature's optimum source of nutrition for infants, can contain undesirable microorganisms that cause severe morbidity. After an outbreak of multidrug‐resistant Escherichia coli among neonates receiving breast milk donated by another mother in our neonatal intensive care unit (NICU), we were motivated to develop a high‐grade breast milk pasteurizer (BMP) designed to thaw and pasteurize breast milk at 63°C for 30 min in a sealed bag without having to open the bag or immerse it in water.MethodsPre‐existing bacteria and spiked cytomegalovirus (CMV) were measured pre‐ and post‐pasteurization in frozen breast milk donated by mothers of children admitted to the NICU.ResultsAmong 48 breast milk samples (mean ± standard deviation [SD]), pre‐existing bacterial counts of 5.1±1.1 × 104 colony forming units (cfu)/mL decreased to less than 10 cfu/mL (below detection level) in 45 samples after pasteurization for 30 min. In three samples, 10–110 cfu/mL persisted. As no CMV was detected in any of the 48 samples, CMV at ≥5 × 104 pfu/mL was spiked into 11 breast milk samples. After just 10 min of pasteurization, infectious CMV was not detected (threshold <50 pfu/mL) in any sample.ConclusionA new BMP was shown to pasteurize milk effectively with more than a 3‐log reduction of microorganisms. Compared to conventional pasteurizers, this device reduces the effort involved in pasteurizing breast milk, avoids various contamination risks, and may reduce the risk of infectious disease transmission via breast milk.

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Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 94%