Profiling of phenolic constituents in Polygonum multiflorum Thunb. by combination of ultra-high-pressure liquid chromatography with linear ion trap-Orbitrap mass spectrometry

Beneficial Effects ofPolygonum multiflorumon Hippocampal Neuronal Cells and Mouse Focal Cerebral Ischemia

“…Previous studies reported that extracts from P. multiflorum have an anti-oxidative property (Ip et al, 1997;Qiu et al, 2013). In line with these studies, our results suggest that the inhibition of intracellular ROS or anti-oxidant roles may be involved in the beneficial effects of WEPM.…”

“…Polygonum multiflorum Thunberg (Polygonaceae) has been widely utilized in East Asian countries as an anti-aging treatment, including treatment of cognitive disorders (Chan et al, 2003;Liu et al, 2011). Phenolic constituents such as anthraquinones, stilbenes, and tannins are well known as major active components of the rhizome extracted from P. multiflorum (Qiu et al, 2013). The tetrahydroxystilbene-glucoside identified from this herb exhibits anti-oxidative and anti-inflammatory activities (Chen et al, 1999;Chiu et al, 2002) and promotes the longterm potentiation of inductions contributing to the enhancement of learning and memory in mice models (Wang et al, 2009.…”

A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry

“…Analysis was performed on a Waters Acquity Ultra Performance LC system Negative ion ionization was used for the detection of more compounds and it had higher sensitivity than the positive mode [14]. The cone gas and the source temperature were set to 50 L/h and 120°C.…”

Microwave-Assisted Extraction of Phenolic Compounds From Polygonum Multiflorum Thunb. Roots

“…So far, scientists have found many new compounds in HTOD, but their structures have not yet been identifi ed (Qiu et al, 2013), especially phenolic compounds. They are used widely in many fi elds, for instance, the food industry and medicine.…”