Profiles of mRNA expression of related genes in the duck hypothalamus–pituitary growth axis during embryonic and early post-hatch development

Hu, Yan; Liu, Hongxiang; Song, Chi; Xu, Wenli; Ji, Gaige; Zhu, Chunhong; JingTing, Shu; Li, Huifang

doi:10.1016/j.gene.2015.01.009

Cited by 6 publications

(5 citation statements)

References 19 publications

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“…In this study, IGF1 expression was lower at E27 compared with E21 and 5 dph in both duck breeds. This expression pattern and level were consistent with that reported by Hu et al[ 3 ], and indicated that IGF1 may play an important role in PM development in ducks. IGF2BP3 (IGF2 mRNA-binding protein 3), as a member of the IGF2 mRNA-binding protein family, is expressed mainly during embryonic development[ 30 ].…”

Section: Discussionsupporting

confidence: 92%

“…Higher IGF1 expression levels were found in muscle from E15-E18 with a peak at E17 followed by a decline during chick embryonic development[ 28 ]. We previously reported that IGF1 and MSTN mRNA levels may influence muscle-growth rates in ducks[ 3 ]. IGF1 positively regulates muscle cell differentiation, and affects gene and microRNA expression in this process[ 29 ].…”

Section: Discussionmentioning

confidence: 99%

“…We previously compared body weight, leg and pectoral muscle (PM) masses, and myofiber characteristics between Gaoyou and Jinding ducks during early development[ 2 – 4 ]. We found that the increase in PM mass slowed from embryonic day (E) 21, with no increase from E21 to E25, followed by a slight decrease in mass before hatching (E27), and then an slow increase from hatching to day 7 post-hatching[ 3 ]. Jing et al[ 5 ] and Chen et al[ 6 ] also observed a similar developmental pattern of PM in a meat-type duck breed.…”

Section: Introductionmentioning

confidence: 99%

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Deep RNA sequencing of pectoralis muscle transcriptomes during late-term embryonic to neonatal development in indigenous Chinese duck breeds

et al. 2017

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Pectoral muscle (PM) comprises an important component of overall meat mass in ducks. However, PM has shown arrested or even reduced growth during late embryonic development, and the molecular mechanisms underlying PM growth during the late embryonic to neonatal period in ducks have not been addressed. In this study, we characterized potential candidate genes and signaling pathways related to PM development using RNA sequencing of PM samples selected at embryonic days (E) 21 and 27 and 5 days post-hatch (dph) in two duck breeds (Gaoyou and Jinding ducks). A total of 393 differentially expressed genes (DEGs) were identified, which showed higher or lower expression levels at E27 compared with E21 and 5 dph, reflecting the pattern of PM growth rates. Among these, 43 DEGs were common to all three time points in both duck breeds. These DEGs may thus be involved in regulating this developmental process. Specifically, KEGG pathway analysis of the 393 DEGs showed that genes involved with different metabolism pathways were highly expressed, while genes involved with cell cycle pathways showed lower expression levels at E27. These DEGs may thus be involved in the mechanisms responsible for the phenomenon of static or decreased breast muscle growth in duck breeds during the late embryonic period. These results increase the available genetic information for ducks and provide valuable resources for analyzing the mechanisms underlying the process of PM development.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Deep RNA sequencing of pectoralis muscle transcriptomes during late-term embryonic to neonatal development in indigenous Chinese duck breeds

et al. 2017

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“…In addition, GH is subject to feedback inhibition by peripheral tissue-derived IGF-1. SS/GHRH-GH-IGF-1 forms a hormonal regulatory axis that affects differentiation, proliferation, metabolism and other functions in nearly all tissues [22]. Many studies have found that ghrelin, which is a hormone secreted by the stomach, also has very powerful functions [23].…”

Section: Discussionmentioning

confidence: 99%

Immunisation of the somatostatin gene alters hypothalamic-pituitary-liver gene expressions and enhances growth in Dazu black goats

Qin,

Fang,

Song

et al. 2024

Anim Biosci

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“…Moreover, species-specific differences in gene expression profiles during early pituitary development have been previously shown in domestic birds. In the chicken pituitary, the mRNA expression levels of growth hormone ( GH ) and prolactin ( PRL ) started to increase on embryonic day 16 ( E16 ) and E18, respectively ( Kansaku et al., 1994 ), while those of duck GH and IGF1 started to increase on E25 and E21, respectively ( Hu et al., 2015 ). Although the chicken pituitary transcriptome changes in the post-hatching development have been previously investigated ( Pritchett et al., 2017 ; Ellestad et al., 2019 ), there are still lack of studies on the avian pituitary developmental dynamics during the critical embryo-to-hatchling transition, especially in waterfowls.…”

Section: Introductionmentioning

confidence: 99%

Integrated mRNA and miRNA transcriptome analysis provides novel insights into the molecular mechanisms underlying goose pituitary development during the embryo-to-hatchling transition

Ouyang

et al. 2021

Poultry Science

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It is well established that the endocrine system plays a pivotal role in preparing the avian embryos for the abrupt switch from chorioallantoic to pulmonary respiration during the critical embryo-to-hatchling transition. However, as the master gland of the endocrine system, there has been little research focusing on the molecular mechanisms controlling the development and function of the pituitary gland during the peri-hatch period in birds. In the present study, we aimed to determine the genome-wide mRNA and miRNA transcriptome profiles of the pituitary during the embryo-to-hatchling transition period from embryonic day 22 ( E22 ) to post-hatching day 6 ( P6 ) in the goose ( Anser cygnoides ). Of note, expression of Anser_cygnoides_newGene_32456 and LOC106031011 were significantly different among these 4 stages (i.e., E22, E26, P2, and P6). Meanwhile, the neuroactive ligand-receptor interaction pathway was significantly enriched by the DEGs commonly identified among three pairwise comparisons. At the miRNA transcriptome level, there were not commonly identified DE miRNAs among these 4 stages, while the 418 of their predicted target genes were mutually shared. Both the target genes of DE miRNAs in each comparison and these 418 shared target genes were significantly enriched in the ECM-receptor interaction and focal adhesion pathways. In the predicted miRNA-mRNA interaction networks of these 2 pathways, novel_miRNA_467, novel_miRNA_154, and novel_miRNA_340 were the hub miRNAs. In addition, multiple DE miRNAs also showed predicted target relationships with the DEGs associated with extracellular matrix ( ECM ) components. Among them, expression of novel_miR_120, tgu-miR-92-3p, and novel_miR_398 was significantly negatively correlated with that of LAMC3 (laminin subunit gamma3), suggesting that these miRNAs may regulate pituitary tissue remodeling and functional changes through targeting LAMC3 during development. These identified DE mRNAs and miRNAs as well as their predicted interaction networks involved in regulation of tissue remodeling and cellular functions were most likely to play critical roles in facilitating the embryo-to-hatchling transition. These results provide novel insights into the early developmental process of avian pituitary gland and will help better understand the underlying molecular mechanisms.

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Profiles of mRNA expression of related genes in the duck hypothalamus–pituitary growth axis during embryonic and early post-hatch development

Cited by 6 publications

References 19 publications

Deep RNA sequencing of pectoralis muscle transcriptomes during late-term embryonic to neonatal development in indigenous Chinese duck breeds

Deep RNA sequencing of pectoralis muscle transcriptomes during late-term embryonic to neonatal development in indigenous Chinese duck breeds

Immunisation of the somatostatin gene alters hypothalamic-pituitary-liver gene expressions and enhances growth in Dazu black goats

Integrated mRNA and miRNA transcriptome analysis provides novel insights into the molecular mechanisms underlying goose pituitary development during the embryo-to-hatchling transition

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