Profiles of ARGs and their relationships with antibiotics, metals and environmental parameters in vertical sediment layers of three lakes in China

Ohore, Okugbe Ebiotubo; Addo, Felix Gyawu; Han, Nini; Li, Xin; Zhang, Songhe

doi:10.1016/j.jenvman.2019.109583

Cited by 54 publications

(15 citation statements)

References 44 publications

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“…The frequently reported antibiotics in both influents and effluents include sulfonamides and tetracyclines ranged from a few ng/L to 10 μg/L (Qiao et al, 2018), while some studies in Xinjiang showed that quinolone was present in the highest concentration with hundreds to thousands ng/L, followed by sulfonamides and tetracyclines ranging from tens to hundreds ng/L along the sewage treatment process (Liu et al, 2017). Previous studies demonstrated the correlation between ARGs and other pollutants induced by human activity, such as the concentration of antibiotics, heavy metals, sewage, and livestock (Zhou et al, 2017;Zhang et al, 2018;Ma et al, 2019;Ohore et al, 2020). Therefore, lower antibiotic discharge may alleviate the pressure of ARG pollution.…”

Section: Discussionmentioning

confidence: 99%

The Occurrence and Distribution Pattern of Antibiotic Resistance Genes and Bacterial Community in the Ili River

Yang

et al. 2022

Front. Environ. Sci.

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The emergence of antibiotic resistance genes (ARGs) is a great risk to the ecosystem and human health; however, there are rare systematic studies about the characterization and source identification of ARGs in continental rivers. This study examined the occurrence of bacterial communities and ARGs in the water and soil of the Ili River using bacterial testing and metagenomic sequencing. Total dissolved solids (TDSs) and total bacterial count significantly increased from upstream to downstream sites. Enterococcus showed the highest abundance in Cockdara. Metagenomic sequencing revealed that the bacterial communities of surface water were different from those of nearshore soils. Among the top 10 ARGs, fluoroquinolone and aminoglycoside resistance genes exhibited dominant relative abundance, but only the multidrug resistance gene adeF was common in all water and soil samples. Proteobacteria carried almost 61% of ARGs, suggesting that these could be the main antibiotic-resistant bacteria (ARB) in the Ili River. Proteobacteria and ARB were mainly distributed in Yining city and Cockdara. Furthermore, the distribution pattern among the five sampling sites indicated that human activity and animal husbandry greatly contributed to the ARB and ARG contamination. This study first investigated the occurrence and distribution pattern of ARGs in the Ili River, demonstrating a clear correlation between bacteria and ARGs, and ARGs and mobile genetic elements (MGEs).

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Section: Discussionmentioning

confidence: 99%

The Occurrence and Distribution Pattern of Antibiotic Resistance Genes and Bacterial Community in the Ili River

Yang

et al. 2022

Front. Environ. Sci.

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“…Predictions indicated that global antibiotic consumption in 2030 will be increased up to 200% higher than that in 2015 [4]. At present, antibiotic abuse has received significant worldwide attention, it has led to the rapid up regulation of antibiotic resistance genes, which will pose adverse impacts on humans and other creators in the environment [5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Occurrence, Distribution, and Ecological Risk Assessment of Antibiotics in Different Environmental Media in Anqing, Anhui Province, China

Chen

Zheng

Shen

et al. 2021

IJERPH

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The widespread usage of antibiotics in human and animal medication has brought global concerns over environmental contamination of antibiotic residues. In this study, 16 kinds of antibiotics in different environmental media of water, sediments, and soils in Anqing city, Anhui province were determined by ultra-performance liquid chromatography tandem mass spectrometry. A total of fourteen kinds of antibiotics were detected in surface water, with a total concentration up to 479 ng·L−1, while six kinds of antibiotics were detected in sediment and soil with concentrations ranging from 15.1 to 108 μg·kg−1. Ciprofloxacin (12.8–99.5 ng·L−1) and tetracycline (17.2–225μg·kg−1) antibiotics exhibited the highest concentration in water and soil, respectively. In spatial distribution, the total concentration of antibiotics in surface water from the highest to the lowest followed the order of urban area, mainstream of Wan River, suburbs, tributaries of Wan River, indicating that the level of antibiotic concentration in surface water is positively associated with the frequency of human activities. In addition, the antibiotic mass fraction in agriculture land and fishpond were found higher than that in other sampling sites. Moreover, the environmental risk assessment results showed that ciprofloxacin, erythromycin, ofloxacin, enrofloxacin and tetracycline might pose medium to high risks to algae and bacteria in aquatic ecosystem.

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“…According to the degree on the selection of ARGs, the six metals roughly behave in the order: Cr > Pb > Cd > Ni > Cu > Fe. However, Ohore et al (2020) found that the degree of in uence of metals on ARGs is Cd > Ni > Cu > Zn > Cr. This different research result shows that the impact of heavy metals on soil and sediments is more dependent on speci c environmental characteristics.…”

Section: Heavy Metals and Argsmentioning

confidence: 98%

“…On the other hand, it also promotes the production of two transposases (tnpA-03 and tnpA-04) and intI1, and accelerates the frequency of horizontal transfer of ARGs. In recent research, Ohore et al (2020) have found that Ni has a strong in uence on the selection of ARGs. However, the analysis of the occurrence speciation has not been carried out.…”

Section: Heavy Metals and Argsmentioning

confidence: 99%

Spatial Distribution of Antibiotic Resistance Genes of the Zaohe-Weihe Rivers, China: Exerting a Bottleneck in the Hyporheic Zone

Shen

Yang

Zhang

et al. 2021

Preprint

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The hyporheic zone (HZ) is an active biogeochemical region where groundwater and surface water mix and a potential reservoir for antibiotic resistance genes (ARGs). In this paper, the relative abundance and spatial distribution of ARGs in the HZ media was investigated, taking into consideration both the 5 speciation of 6 metals and the local characteristics. The samples of surface water, groundwater and sediment were collected from Zaohe-Weihe rivers of Xi’an City, which is representative cities with characteristics of the north-west region region of China. Of 271 ARGs associated with 9 antibiotics, 228 were detected, with a total detection rate of 84%. Sulfonamide and aminoglycoside ARGs were the dominant types of ARGs. The top 6 ARGs and mobile genetic elements (MGEs) in terms of abundance were tnpA-04, cepA, sul1, aadA2-03, sul2 and intI1. The results of principal component analysis (PCA) showed that the distribution characteristics of ARGs were not associated with the sampling sites but with the environmental medias. Similarity in the water phases and significant differences in the water and sediment phases were found. The redundancy analysis (RDA) identified the key factors controlling ARG pollution, including dissolved oxygen (DO) in surface water, total nitrogen (TN) in groundwater and total organic carbon (TOC) in sediments. In terms of the speciation of heavy metals, we further revealed the promotion effect between ARGs and heavy metals, especially the residual fraction of Ni. In terms of horizontal transfer mechanism, ARGs were significantly correlated with tnpA-03 in water phase, and were significantly correlated with tnpA-04 in sediment. In the three media, intI1 and ARGs, all show a significant correlation. These findings showed that hyporheic zone exerted a bottleneck effect on the distribution and transfer of ARGs.

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Profiles of ARGs and their relationships with antibiotics, metals and environmental parameters in vertical sediment layers of three lakes in China

Cited by 54 publications

References 44 publications

The Occurrence and Distribution Pattern of Antibiotic Resistance Genes and Bacterial Community in the Ili River

The Occurrence and Distribution Pattern of Antibiotic Resistance Genes and Bacterial Community in the Ili River

Occurrence, Distribution, and Ecological Risk Assessment of Antibiotics in Different Environmental Media in Anqing, Anhui Province, China

Spatial Distribution of Antibiotic Resistance Genes of the Zaohe-Weihe Rivers, China: Exerting a Bottleneck in the Hyporheic Zone

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