Profile of Solid Tumor Patients Complicated With Venous Thromboembolism: A 10-Year Retrospective Cross-Sectional Study Based on 1482 Cases

Li, Huimin; Tian, Yu; Niu, Haiwen; He, Lili; Cao, Guolei; Zhang, Changxi; Kaiweisierkezi, Kaiseer; Luo, Qin

doi:10.1177/10760296231169514

Cited by 1 publication

(1 citation statement)

References 46 publications

(95 reference statements)

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“…CVCs play a key role in inpatient settings, where they provide reliable central venous access for medium to long-term intravenous drug therapy. Numerous studies [33,34] have shown a strong association between long-term CVC use and the risk of upper extremity deep vein thrombosis (UEDVT). Consistent with these ndings, our study also identi ed CVCs as a major contributor to UEDVT.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for venous thromboembolism in hospitalized patients: A cross sectional study

Zhang¹,

Li²,

Yang³

et al. 2023

Preprint

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Background Venous thromboembolism (VTE) is a multifactorial disease that is associated with long-term morbidity, dysfunction, and mortality. Although numerous studies have reported on the incidence and risk factors of VTE in hospitalized patients, the reported results vary due to the complexity of the disease and differences in genetic characteristics, social environment, and disease spectrum. Therefore, the aim of this study was to investigate the incidence, clinical features, and risk factors for VTE in hospitalized patients. Methods A cross-sectional study was conducted at Benxi Central Hospital to select patients hospitalized between January and December 2021. All patients underwent Doppler ultrasound, and medical data, including demographic characteristics, past medical history, comorbidities, and hematologic indicators, were collected from the Benxi Clinical Biobank. Chi-square tests and logistic regression analysis were employed to identify independent risk factors. Results A total of 1200 in-patients were eligible for inclusion in the study. The prevalence of venous thromboembolism was 21.4%. 224 patients developed DVT alone, 12 patients developed PE alone, and 14 patients developed both DVT and PE. Of the 238 patients with DVT in the lower limbs (with or without PE), distal DVT was more common than proximal DVT (64.7%vs20.2%). In multifactorial analysis, six variables are independent risk factors for VTE:Diabetes,OR,1.659,(1.100-2.501, P = 0.016);History of confirmedVTE,OR,6.497,(3.505–12.041,P = 0.000);Central venous catheterization,OR,2.605,(1.583–4.289,P = 0.000);Age,OR,1.035,(1.022–1.048,P = 0.000);HGB,OR,0.993,(0.987-1.000, P = 0.042);Unilateral limb pitting oedema,OR,5.307,(3.506–8.033, P = 0.000);Bilateral limb pitting oedema,OR,1.701,(1.081–2.676,P = 0.022). Conclusion The incidence of VTE among hospitalized patients in Benxi region is relatively high. Identifying relevant risk factors allows for early screening of at-risk populations. In order to reduce prevalence, and more prospective studies are needed to comprehensively develop individualised clinical prediction tools for VTE.

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Section: Discussionmentioning

confidence: 99%