Profile of Non-Neoplastic and Neoplastic Thyroid Lesions by Fine Needle Aspiration Cytology and their Correlation with Histopathology-A One Year Prospective Study in a Teaching Hospital

Abstract

FNAC is highly cost effective, patient friendly outpatient procedure with minimal discomfort and gives basic to accurate information regarding the lesions. It is considered as first line investigative technique as it gives quick results with good sensitivity and specificity. It also stratifies cases requiring further investigations, surgical intervention or just clinical follow-up. Present study is about the profile of non-neoplastic and neoplastic thyroid lesions by Fine needle aspiration cytology and correlates the FNAC findings with the histopathology. This study was undertaken in the

Incident of Thyroid Carcinomas and Other Pathologies with Age Correlation in Patients Presented with Palpable Thyroid Masses Undergoing Thyroidectomies

“…5 In Pakistan the overall incidence of thyroid carcinoma is 1.2% with papillary thyroid carcinoma comprising 69-71%, follicular thyroid carcinoma 11-13%, medullary thyroid carcinoma 3-5% and anaplastic thyroid carcinoma 1-2%. 6 The exact diagnosis of thyroid lesion requires histopathology on thyroidectomy specimens 7 . Different modalities are employed for early detection of the lesions such as Ultrasound, thyroid scan and Fine Needle www.apmcfmu.com Aspiration Cytology.…”

“…Different modalities are employed for early detection of the lesions such as Ultrasound, thyroid scan and Fine Needle www.apmcfmu.com Aspiration Cytology. 7 Recommendations are that all thyroid nodules greater than 1cm in size must be evaluated thoroughly to rule out malignancy. 8 Among general population, most of these nodules are benign and only 5-25% represents thyroid cancer.…”

“…Clinically it presents with rapid thyroid enlargement, dyspnea and dysphagia. 7 The benign non neoplastic conditions include multinodular goiter, various types of thyroiditis including Hashimoto's thyroiditis, de Quervain thyroiditis, lymphocytic thyroiditis and palpation thyroiditis. The thyroid adenomas include follicular adenoma, Hurthle cell adenoma and hyalinizing trabecular adenoma.…”

“…It occurs due to iodine deficient diet especially in iodine deficient areas. 7 Toxic multinodular goiter (multinodular goiter) is one of the causes of hyperthyroidism, after Grave's disease. 6 Follicular adenoma is a benign tumor exhibiting follicular differentiation microscopically without vascular and capsular invasion.…”

“…6 Follicular adenoma is a benign tumor exhibiting follicular differentiation microscopically without vascular and capsular invasion. 7 The aim of this study was to determine the incidence of thyroid cancer and its correlation with different age groups. Patient's data was recorded on predesigned proforma.…”