Profile of neonates born with congenital birth defects in a tertiary care hospital of North India: An observational study

Sinha, Abhilasha; Tripathi, Shalini; Nigam, Neetu; Kumar, Madhu; Singh, SK

doi:10.1016/j.cegh.2022.100999

Cited by 6 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11 Cleft palate followed by CTEV is the most common congenital anomaly in our study whereas CTEV is the most common in Sinha et al study. But the incidence of cleft palate (6.4%) in Sinha et al study is similar to our study report.…”

mentioning

confidence: 46%

“…In the Sinha et al study, male newborns showed a somewhat greater prevalence of deformity (p=0.064) Numerous Indian studies back up the results. 11 The fact that there are still some areas of India where female newborns are deemed undesired pregnancies and are terminated may help to explain the rising male preponderance. Sachdeva et al observed a higher frequency of deformity in female infants, which is contrary to our findings.…”

Section: Risk Factors Of the Problemmentioning

confidence: 99%

See 1 more Smart Citation

Magnitude, risk factors and immediate outcome of external congenital anomalies in neonates in government Cuddalore medical college and hospital: an observational study

Ramanathan,

Mahalakshmi

2024

Int J Contemp Pediatr

View full text Add to dashboard Cite

Background: Despite the enormous incidence of congenital malformations in developing countries, there are presently few thorough data on these disorders because there are no birth defect registries. This study was conducted with objectives to determine the magnitude, risk factors and outcomes of external congenital anomalies in neonates born in government Cuddalore medical college and hospital. Methods: The present study is an observational study. All the neonates born during the study period were included in our study and risk factors and outcome of 201 babies born with external congenital anomalies were analyzed in detail. Results: The incidence of external congenital anomalies is 5.68% with 33% having major and 63% having minor anomalies. Among the major anomalies cleft lip and/or palate is the most common anomaly (5%) in our study. Overall sacral dimple is the most commonly observed external congenital anomaly (9.50%). Four-fifths of the newborns with external congenital anomalies were discharged. About 13% of the newborns with congenital anomalies expired. Conclusions: A comprehensive package that includes preventive services, diagnostic, surgical or medical intervention, financial assistance, counselling, and psychosocial support, as well as follow-up treatments like rehabilitation, is required in combating the incidence of congenital anomalies.

show abstract

mentioning

confidence: 46%

Section: Risk Factors Of the Problemmentioning

confidence: 99%

Magnitude, risk factors and immediate outcome of external congenital anomalies in neonates in government Cuddalore medical college and hospital: an observational study

Ramanathan,

Mahalakshmi

2024

Int J Contemp Pediatr

View full text Add to dashboard Cite

show abstract

“…A meta-analysis conducted by Bhide and Kar showed a pooled prevalence rate of 184.48 CAs per 10000 live births [ 7 ]. Studies from North India and North Kerala also reported lower incidences of 1.7% and 0.84%, respectively [ 4 , 10 ]. In a retrospective study conducted by Kumar et al over a period of 20 years (1998-2017), the prevalence rate was reported as 182 per 10000 live births [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence and Pattern of Congenital Anomalies Among Neonates Admitted in a Tertiary Care Hospital in the Andaman and Nicobar Islands: A Retrospective Study

Sravani,

Palaniappan,

Shaju

2023

Cureus

View full text Add to dashboard Cite

Introduction Congenital anomalies (CAs) constitute a significant determinant of neonatal mortality in India, and past studies have elucidated their diverse clinical presentations across different geographic regions. Given the limited availability of region-specific data in our locale, this study was initiated to elucidate the prevalence and phenotypic manifestations of congenital anomalies in live births within the distinctive setting of the Andaman and Nicobar Islands, India. Methods This retrospective observational study was conducted at the Department of Pediatrics of the Andaman and Nicobar Islands Institute of Medical Sciences (ANIIMS), located in Port Blair, during a defined one-year period extending from June 2022 to May 2023. All live births presenting with congenital anomalies within this stipulated timeframe were systematically enrolled in the study, and data was meticulously extracted from their respective medical records. The study data was methodically collated and organized utilizing the EpiData software (EpiData Association, Odense, Denmark), followed by a comprehensive descriptive analysis executed through the application of the PSPP software (GNU Project, Boston, MA). Results Among the 1661 neonates admitted during the study's defined period, a total of 61 neonates (3.7%) were identified as having congenital anomalies. Among these anomalies, cardiovascular anomalies were found to be the most prevalent, succeeded by gastrointestinal and central nervous system anomalies. Notably, major congenital anomalies were discerned in 20 out of 61 neonates, constituting approximately 33% of the neonatal population with anomalies. Neonates afflicted with congenital anomalies displayed a mortality rate of 11.5%. Conclusion The effects of congenital anomalies on individuals, families, and the society are far-reaching. Early identification and timely referral and intervention are the key factors in decreasing the mortality and morbidity associated with congenital anomalies.

show abstract

“…The mortality rate associated with malformations is very high in this study, with more than half of malformed neonates dying. Other authors have reported more moderate mortality rates, such as Madhura et al [13] (8%), Bénié et al [5] (11%), Kaboré et al [12] at 13.9%, and Sinha et al [39] at 30.5%. This result lies between the significantly higher rates observed in other African countries, such as Mozambique according to Cavalière et al [36] (50%) or the DRC according to Mashako et al [10] (59.6%).…”

Section: Outcomementioning

confidence: 96%

Visible Congenital Malformations in Ouagadougou (Burkina Faso)

Nagalo,

Konaté,

Douamba

et al. 2023

AJPR

View full text Add to dashboard Cite

Objective: To gain a better understanding of congenital malformations and to help reduce neonatal morbidity and mortality, particularly in a context of resource-limited countries. Methods: This descriptive cross-sectional study with retrospective and prospective data collection over the period from November 2019 to January 2022 was conducted in the Neonatology Unit of the Centre Hospitalier Universitaire Pédiatrique Charles de Gaulle of Ouagadougou, Burkina Faso (West Africa). Records of neonates with a visible malformation, neonates whose parents were accessible by telephone were included. Results: The frequency of congenital malformations was 8.4%. They affected females (51.1%), first-born siblings (25%) and full-term babies (69.6%). Osteoarticular malformations (38%), those of the eye, ear, face and neck (22.81%), followed by those of the digestive system (21.64%) were the most frequent. The case-fatality rate was 51.5%. Conclusion: Visible congenital malformations are a major cause of morbidity and mortality among neonates in our unit. To help reduce the morbidity and mortality associated with malformations, awareness-raising, early detection, prevention and improved medical care for affected neonates are needed. This is all the more true in countries where medical resources may be limited and surveillance systems need to be put in place.

show abstract

Profile of neonates born with congenital birth defects in a tertiary care hospital of North India: An observational study

Cited by 6 publications

References 21 publications

Magnitude, risk factors and immediate outcome of external congenital anomalies in neonates in government Cuddalore medical college and hospital: an observational study

Magnitude, risk factors and immediate outcome of external congenital anomalies in neonates in government Cuddalore medical college and hospital: an observational study

The Prevalence and Pattern of Congenital Anomalies Among Neonates Admitted in a Tertiary Care Hospital in the Andaman and Nicobar Islands: A Retrospective Study

Visible Congenital Malformations in Ouagadougou (Burkina Faso)

Contact Info

Product

Resources

About