Profile of Nasopharyngeal Cancer Patients who Underwent Radiotherapy in Dr. Hasan Sadikin General Hospital Bandung

Abstract

Background: Nasopharyngeal cancer (NPC) is a malignant epithelial tumor located in the nasopharynx and is the most common head and neck malignancy. This study aimed to find and describe the profile of NPC patients who undergo radiotherapy at Dr. Hasan Sadikin General Hospital, Bandung.Methods: This study was a descriptive study conducted at the Department of Radiology of Dr. Hasan Sadikin General Hospital, Bandung. This study employed a total sampling method and was done by observing patients’ status/medical records from January 1, 2018, to December 31, 2019, which was registered based on the Hospital-Based Cancer Registry (HBCR). The inclusion criteria were all patients diagnosed with NPC and undergone radiotherapy.Results: There were 274 records (19.74%) included as NPC from 1,388 records. This cancer was more frequent in men (70.4%), in the age group of 45–54 years (35.0%), non-active smokers (58.8%), entrepreneurs (23.0%), and those who came from West Priangan (36.1%). The most common chief complaint was an enlargement of neck lymph nodes (55.1%) at stage IVB (42.8%). Histopathological findings were dominated by undifferentiated squamous cell carcinoma (WHO III) (74.4%). Most of the patients were treated with chemoradiation (64.3%).Conclusions: NPC could happen to anyone with different background. This study found it was more frequent in men than women (2.3:1), in the fourth and fifth decade of life, in entrepreneurs followed by housewives, and even in non-active smokers. It also could happen in children to the elderly. Most patients came with an enlargement of neck lymph nodes as their chief complaint in the advanced stage and need chemoradiation as their treatment.

Profile of Nasopharyngeal Carcinoma in Dr. Wahidin Sudirohusodo Hospital Makassar 2011 – 2021

“…In this study, the most developed symptom was a palpable lump in the neck (28.8%). According to the results of this study and research conducted by Nafisa, et. al (2022) the most common chief complaint was an enlargement of neck lymph nodes (55.1%).…”

“…Moreover, the second most common complaint was nasal congestion (23.5%). (2,8) According to Jayalie, et. al.…”

“…The most prevalent head and neck cancer in Indonesia is nasopharyngeal carcinoma (NPC), a malignant epithelial tumor that develops in the nasopharynx. (1,2) Southeast Asia is mainly where NPC is more prevalent. (1) With a total incidence estimated at 6.2/100,000 or 12,000 new cases annually, it continues to be a health burden in Indonesia.…”

Analysis of Radiation Dose Distribution in Nasopharyngeal and Organ Cancer Cases at Risk with Linear Accelerator Radiotherapy 6 MV Photon Energy Using the IMRT Technique at Prof. Hospital. Dr. I. G. N. G. Ngoerah

“…The nasopharyngeal carcinoma (NPC) is a type of cancerous tumor that arises from the epithelial cells and occurs in the nasopharynx. It is a prevalent form of malignancy in the head and neck area [1]. NPC in Indonesia is one of the most frequently found malignancies, ranking fifth after breast cancer, cervical cancer, lung cancer, and liver cancer.…”

Profile of Nasopharyngeal Carcinoma in Dr. Wahidin Sudirohusodo Hospital Makassar 2011 – 2021

“…Nasopharyngeal carcinoma (NPC) is a tumor arising from the epithelial cells that cover the surface and line the nasopharynx and is the most common head and neck malignancy in Indonesia (1,2). NPC is generally more common in Southeast Asia (1).…”