Profile of Galanin in Embryonic Stem Cells and Tissues

Lautatzis, Maria-Elena; Vrontakis, Maria

doi:10.5772/23771

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2017

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“…Galanin is involved in the regulation of physiological processes in peripheral organ systems via neuronal mechanisms and direct receptor mediated cellular effects. Currently three types of galanin receptors (GalR1, GalR2, and GalR3) have been identified by molecular cloning and characterized pharmacologically in various species [ 9 ]. They are members of the G-protein coupled receptor superfamily, but have differences in their functional coupling and signaling activities.…”

Section: Introductionmentioning

confidence: 99%

Myocardial protection from ischemia/reperfusion injury by exogenous galanin fragment

et al. 2017

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Background and purpose: Galanin is a multifunctional neuropeptide with pleiotropic roles. The present study was designed to evaluate the potential effects of galanin (2-11) (G1) on functional and metabolic abnormalities in response to myocardial ischemia-reperfusion (I/R) injury. Experimental approach: Peptide G1 was synthesized by the 9-fluorenylmethoxycarbonyl (Fmoc)-based solid-phase method. The chemical structure was identified by

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Section: Introductionmentioning

confidence: 99%