Profile of extrahepatic portal venous obstruction among children in Central India

Abstract

IntroductionThere is a paucity of data regarding the clinical profile of children with extrahepatic portal venous obstruction (EHPVO) from Central India.Material and methodsRetrospective analysis of 30 children with EHPVO treated between 2002 and 2012.ResultsThe median age of presentation was 12.5 years (range 5-14 years) and median duration of symptoms was 3.2 years (range 0.3-10 years). Home delivery was noted in 30 cases (100%), umbilical sepsis in 8 (27%) and history of cow dung application over the umbilical cord in 2 cases (6.7%). Twenty-two cases (73.4%) presented with upper gastrointestinal (GI) bleeding while 18 (60%) were referred for pancytopenia and/or hypersplenism. The patients underwent a median of 3.2 sessions of endoscopic therapy for varices. Most patients (19/30, 63.4%) dropped out of serial endotherapy due to the paucity of funds. Shunt surgery was performed in 7 patients.ConclusionsHome delivery and umbilical sepsis are significant risk factors for EHPVO. Most patients present with GI bleeding and do well on endoscopic treatment/shunt surgery.

Extra Hepatic Portal Vein Obstruction with Solitary Left Kidney: A Case Report

“…2 In adults, EHPVO is rare and common causes includes hypercoaguable states, trauma, myeloproliferative diseases and invasion by tumors. 2,3 In majority of cases the cause remains unidentified. 2,3 Most common clinical presentation is upper gastrointestinal bleeding, incidental finding of splenomegaly, poor growth in cases of children and bleeding tendencies.…”

“…2,3 In majority of cases the cause remains unidentified. 2,3 Most common clinical presentation is upper gastrointestinal bleeding, incidental finding of splenomegaly, poor growth in cases of children and bleeding tendencies. 2 If left untreated mortality may occur due to bleeding tendencies and infections.…”

“…2 In adults, EHPVO is rare and common causes includes hypercoaguable states, trauma, myeloproliferative diseases and invasion by tumors. 2 , 3 In majority of cases the cause remains unidentified. 2 , 3 …”