Profile and determinants of vascular cognitive impairment in African stroke survivors: The CogFAST Nigeria Study

Akinyemi, Rufus; Allan, Louise; Owolabi, Mayowa; Akinyemi, Joshua; Ogbole, Godwin; Ajani, Akinlolu A.; Firbank, Michael; Ogunniyi, Adesola; Kalaria, Raj N.

doi:10.1016/j.jns.2014.08.042

Cited by 76 publications

(92 citation statements)

References 70 publications

(106 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cohorts were either population based (primary care) (n = 8) [11,12,13,14,15,16,17,18], hospital based (general secondary care) (n = 7) [19,20,21,22,23,24,25], specialist centres (tertiary care based, referred by a specialist clinic, e.g., memory, cardiovascular hospital clinic) (n = 14) [26,27,28,29,30,31,32,33,34,35,36,37,38] or mixed research centre and hospital based (n = 1) [39]. Many studies only included individuals above a certain age (e.g., ≥45 years [39], ≥65 years [11,12,13,14,15,16,18,34] or ≥75 years [17,20,25]).…”

Section: Resultsmentioning

confidence: 99%

“…Many studies only included individuals above a certain age (e.g., ≥45 years [39], ≥65 years [11,12,13,14,15,16,18,34] or ≥75 years [17,20,25]). Fourteen studies were based on populations with a previous history of stroke [19,20,21,22,23,24,25,26,27,28,37,38,39,40]. …”

Section: Resultsmentioning

confidence: 99%

“…The most commonly used criteria for dementia case exclusion were the Diagnostic and Statistical Manual of Mental Disorders (DSM)-III-revised [11,12,14,16,18,20,25,31,32,34,35,36] or the DSM-IV criteria [13,15,21,22,28,38,39,40]. Also used were the Clinical Dementia Rating (CDR) of 1+ [17], medical history [26,27], clinical diagnosis [29,30] and Mini Mental State Examination (MMSE) score ≤21 [33], or, in the case of one study, below the second percentile on the Korean MMSE [21].…”

Section: Resultsmentioning

confidence: 99%

“…Some studies (n = 4) [26,27,28,39] also reported variable criteria and prevalence rates for different types of VCI-ND (e.g., mild or moderate, amnestic or non-amnestic, single domain or multiple domain) which ranged from 3 to 41% depending on the classification of VCI-ND [26,27,28,39], and one study used more than one definition to compare prevalence rates of VCI-ND (range 10-50% depending on definition) [21]. …”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Harrison¹,

Tang²,

Keage³

et al. 2016

Dement Geriatr Cogn Disord

Self Cite

View full text Add to dashboard Cite

Background/Aims: No set operational criteria for vascular cognitive impairment, no dementia (VCI-ND) have yet been established. The aim of this study is to undertake a systematic review to compare definitions of VCI-ND that have been used in cohort studies. Methods: Medline, PsycINFO and Embase were searched from inception to October 13, 2015. Initially, 3,142 records were screened, and 30 were included in this review. Results: No single set of criteria for defining VCI-ND was identified. VCI-NDwas broadly defined as an absence of dementia, cognitive impairment in at least one cognitive domain with signs of vascular involvement, and intact activities of daily living. Conclusion: Defining criteria will enable individuals with VCI-ND to be efficiently compared across cohort studies to more accurately determine the prevalence and risk of dementia.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Harrison¹,

Tang²,

Keage³

et al. 2016

Dement Geriatr Cogn Disord

Self Cite

View full text Add to dashboard Cite

show abstract

“…Our search identified 523 articles, of which 5 met the inclusion criteria (none were population based [50][51][52][53][54] ; Results and Table V in the online-only Data Supplement). A variety of cognitive tests were used.…”

Section: Poststroke Depressionmentioning

confidence: 99%

Focused Update of Sex Differences in Patient Reported Outcome Measures After Stroke

Gall

Phan

Madsen

et al. 2018

Stroke

View full text Add to dashboard Cite

W omen experience worse outcomes after stroke than men 1 despite their lower age-adjusted incidence of stroke.2 Previous reviews of sex differences in select stroke outcomes, including activity limitations, 3-5 participation restriction, 4 poststroke depression (PSD), 3 and health-related quality of life (HRQoL), 3,4 demonstrated that women had worse outcomes than men across many of these measures. Women's greater age and stroke severity, as well as poorer prestroke function, seem to contribute to the sex difference in outcomes, but data on other contributing factors are limited.4 Existing reviews included studies published >5 years ago, and given the rapid increase in the number of studies addressing sex differences in stroke outcomes, an updated review is warranted. MethodsFull details of our methods are provided in the online-only Data Supplement. A previous review included studies up to 2007, 3 so we reviewed studies from 2007 onwards that examined sex differences in patient reported outcome measures (PROMs) at ≤12 months after stroke, including activity limitations, HRQoL, participation restriction, impaired cognition, and mood. 6 Full results tables are shown in the online-only Data Supplement. Results Activity LimitationsOf 1875 articles identified, 22 studies (3 population based) that were designed to examine sex differences (Results and Table I in the online-only Data Supplement) met criteria for inclusion. The most common instrument to assess activity limitations was the modified Rankin Scale, followed by the Barthel Index.In 8 studies including ischemic and hemorrhagic strokes, unadjusted estimates showed that women had more activity limitations than men through significantly lower odds of good outcome (odds ratio [OR] range: 0.44-0.61) 7-9 or greater odds of poor outcome (OR range: 1.29-1.62).10-14 In multivariable adjusted analyses, women had worse outcome than men with significantly lower odds of good outcome (OR range: 0.37-0.75) or greater odds of poor outcome (OR range: 1.17-1.74). 7,8,10,12,13 In 2 studies, there was no statistically significant difference between women and men.11,14 Adjustment for covariates, most commonly age, stroke severity, comorbidities, and prestroke function, reduced the associations between 9% and 20%, suggesting these factors partly explain the greater activity limitations for women after stroke.In 11 studies of ischemic stroke ( Table I in the online-only Data Supplement), women generally had worse outcome than men demonstrated by greater odds of poor outcome (mostly modified Rankin Scale ≥3 versus <3; range in ORs: 1.13-2.40) or lower odds of good outcome (eg, modified Rankin Scale ≤1 versus >1 or independent walking).15-25 Among 13 multivariable adjusted comparisons between men and women (some studies had >1 comparison), women's significantly worse outcome compared with men persisted in 7 comparisons with a greater odds of poor outcome (range, 1.30-3.40) or a higher activities of daily living score. [17][18][19][22][23][24] Common covariates included age, stro...

show abstract

Dementia in Africa: Current evidence, knowledge gaps, and future directions

Akinyemi

Yaria

Ojagbemi

et al. 2021

Alzheimer's & Dementia

Self Cite

View full text Add to dashboard Cite

In tandem with the ever-increasing aging population in low and middle-income countries, the burden of dementia is rising on the African continent. Dementia prevalence varies from 2.3% to 20.0% and incidence rates are 13.3 per 1000 person-years with increasing mortality in parts of rapidly transforming Africa. Differences in nutrition, cardiovascular factors, comorbidities, infections, mortality, and detection likely contribute to lower incidence. Alzheimer's disease, vascular dementia, and human immunodeficiency virus/acquired immunodeficiency syndrome-associated neurocognitive disorders are the most common dementia subtypes. Comprehensive longitudinal studies with robust methodology and regional coverage would provide more reliable information. The apolipoprotein E (APOE) ε4 allele is most studied but has shown differential effects within African ancestry compared to Caucasian. More candidate gene and genome-wide association studies are needed to relate to dementia phenotypes.Validated culture-sensitive cognitive tools not influenced by education and language differences are critically needed for implementation across multidisciplinary groupings such as the proposed African Dementia Consortium.

show abstract

Profile and determinants of vascular cognitive impairment in African stroke survivors: The CogFAST Nigeria Study

Cited by 76 publications

References 70 publications

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Focused Update of Sex Differences in Patient Reported Outcome Measures After Stroke

Dementia in Africa: Current evidence, knowledge gaps, and future directions

Contact Info

Product

Resources

About