Profil histologique et évolutif de l’hypertension artérielle chez les patients atteints d’une néphropathie lupique

Aoudia, R.; Omrane, M.; Gaied, H.; Jerbi, M.; Jaziri, F.; Barbouch, S.; Kâaroud, H.; Hedri, H.; Abdallah, T. Ben; Goucha, R.

doi:10.1016/j.nephro.2017.08.020

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In sub-Saharan Africa, studies found a prevalence ranging from 30% to 29.3% [ 12 , 13 ]. On the other hand, the prevalence of hypertension was higher in the series of Contreras et al [ 14 ] with 70% of cases, of Aoudia et al [ 8 ] with 48.85% of cases, and of Martin-Gomez et al [ 15 ] with 54.1% of cases. Based on these results, it was found that the prevalence of hypertension in our study was lower than in studies done in white patients.…”

Section: Discussionmentioning

confidence: 88%

“…Proliferative glomerulonephritis was defined by classes III or IV associated or not with a class V according to the classification of the ISN/RPS of 2003 [ 7 ]. Hypertension was defined according to the definition of the World Health Organization [ 8 ]. For each patient retained, epidemiological, clinical, biological, histological, therapeutic, and evolutionary data were studied.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Proliferative Glomerulonephritis: Risk Factor for Hypertension in Lupus

Mbengue¹,

Lot

Diagne

et al. 2021

International Journal of Hypertension

View full text Add to dashboard Cite

Studies report a high prevalence of hypertension in lupus, reaching up to 74%. The incidence of hypertension in SLE patients is increased with the severity of the kidney damage. This work was carried out with the objective of determining the prevalence of hypertension in lupus nephritis and to seek the existence of an association between the presence of a proliferative glomerulonephritis and hypertension. Patients and Methods. This was a case-control study, carried out in the nephrology department of the Aristide Le Dantec University Hospital in Dakar. All records of patients with lupus nephritis over a 10-year period, from January 01, 2007, to December 31, 2016, were included. Results. During the study period, out of 64 lupus nephritis records collected, 28 patients had hypertension, for a hospital prevalence of 43.75%. The mean age of the patients was 30.64 years ± 10.44. There were 24 women and 4 men. The mean systolic blood pressure was 156 mmHg (110–220) and the mean diastolic blood pressure was 100 mmHg (80–130). The mean serum creatinine was 29.48 mg/l ± 24.99. The mean proteinuria was 4.50 g/24 h ± 2.87. Hypertriglyceridemia was observed in one patient. Hypercholesterolemia was present in 3 patients. HDL levels were normal in all patients and elevated LDL levels were noted in all 4 patients. None of our patients had diabetes. Class III was found in 11 cases, class IV in 14 cases, pure class V in 2 cases, and class II in 1 case. Hypertension was associated with the presence of proliferative glomerulonephritis (odds ratio, 7.45; 95% CI, 1.9 to 29.1; p = 0.002 ). Conclusion. Hypertension is common in lupus nephritis. The presence of a proliferative glomerulonephritis is a risk factor for the development of arterial hypertension. Screening and adequate management of hypertension are essential for the prevention of the progression of chronic kidney disease in lupus.

show abstract

Section: Discussionmentioning

confidence: 88%

Section: Methodsmentioning

confidence: 99%