Profil épidémiologique et clinique des enfants atteints de la maladie à Corona Virus (COVID-19) au Centre de Traitement des Epidémies et Prévention des Infections (CTEPI) du CHU de Donka à Conakry

Camara, Emmanuel; Barry, Ibrahima; Diallo, Fatoumata; Diallo, Malick; Diop, Mamadou; Chérif, Mahamoud Sama; Diallo, Ibrahima; Kouyaté, M.; Bangoura, M.; Barry, Aïssata; Barry, Mamadou Ciré; Ngadande, Ipolithe Honde; Kaba, Oumar; Kolié, Ouo Ouo; Camara, D.; Diallo, S; Dia, Hasmiou

doi:10.11604/pamj.2020.37.363.26211

Cited by 8 publications

(7 citation statements)

References 11 publications

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“…With an age range of 0 -19 years, it had a mean age of 10.89 ± 7 years. This result was different from that of Camara et al [4] who evaluated the epidemiological and clinical profile of children with COVID in a town in Guinea. It had a more predominant age range of 0 -4 years and an average age of 7 years.…”

Section: Discussioncontrasting

confidence: 97%

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Comparison of the Clinical Profile and Severity Factors of COVID-19 during the First 4 Waves in a Paediatric Population of Yaounde

Nengom¹,

Um²,

Nlend³

et al. 2023

OJPed

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Introduction: COVID-19 is an infectious disease that has been causing a global pandemic since 2019. Although clinical forms are generally less severe in children than in adults, children nevertheless present polymorphous clinical forms and severe cases that can lead to death. Objective: To describe the clinical presentations found in the different waves of COVID-19, and to highlight the different factors of severity. Materials and Methods: We conducted a cross-sectional study with retrospective and prospective data collection which lasted 7 months (from November 2021 to June 2022) and covered a study period from 6 March 2020 to 22 June 2022, i.e. 27 months. All patients aged 0 to 18 years, suspected of having COVID-19, confirmed by real-time RT-PCR or an antigenic Rapid Diagnostic Test or antibody were included.These patients were to be managed in the Mother and Child Centre of the Chantal Biya Foundation, as well as in the Specialised Centre for the Management of COVID patients, annex number II of the Yaoundé Central Hospital. The results were analysed using IBM SPSS.23 software. Results: We included 163 patients in our study. No paediatric patients were registered during the 3 rd wave. The mean age of the patients in the study population was 13 ± 5 years with extremes from 15 days to 18 years. We had a female predominance with a sex ratio of 0.83. The most common comorbidity was asthma. The first wave presented mainly with respiratory symptoms such as dry cough and signs of respiratory distress. The second wave presented mainly with digestive symptoms such as diarrhoea, abdominal pain and vomiting. The fourth wave presented with ENT signs such as sore throat, and rhinorrhea. Factors associated with severity were mainly age less than five years (OR = 17.69), vomiting (OR = 6.50

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Section: Discussioncontrasting

confidence: 97%

“…The sex ratio was 0.83. This is similar to the study by Camara et al [4] who found a female predominance of 60.32%, this predominance in Camara was due to the demography of Guinea, which is predominantly female. But a study by Meguieze et al in the vicinity of Yaoundé [2] showed a male predominance of 52%.…”

Section: Discussionsupporting

confidence: 92%

Comparison of the Clinical Profile and Severity Factors of COVID-19 during the First 4 Waves in a Paediatric Population of Yaounde

Nengom¹,

Um²,

Nlend³

et al. 2023

OJPed

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“…En Guínea, Camara et al, 15 al analizar a niños menores de 17 años, entre los que predominaron las muje- En la curva de casos confirmados por día de inicio de síntomas se distingue claramente el incremento del número de casos entre noviembre de 2020 y febrero de 2021, hecho que no se visualiza entre marzo y noviembre, donde la curva se mantuvo con nuevos casos confirmados no tan elevados (Figura 1).…”

Section: Discussionunclassified

Análisis de casos de COVID-19 y su fatalidad en mujeres menores de 19 años en México: un estudio transversal

Barroso¹,

Flores-Vargas²,

Luna³

et al. 2021

Archivos De Investigación Materno Infantil

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“…Approximately 4 million children in the United States were reported to have been infected with coronavirus disease 2019 (COVID‐19) as of May 2021 1–3 . Although most children had mild or asymptomatic disease, several thousands required hospitalization, and hundreds have died due to the disease and its complications.…”

Section: Introductionmentioning

confidence: 99%

“…Approximately 4 million children in the United States were reported to have been infected with coronavirus disease 2019 (COVID-19) as of May 2021. [1][2][3] Although most children had mild or asymptomatic disease, several thousands required hospitalization, and hundreds have died due to the disease and its complications. Children with compromised disease states are more likely to experience severe effects of COVID-19; however, even healthy children develop severe disease, according to the Centers for Disease Control and Prevention.…”

Section: Introductionmentioning

confidence: 99%

Coronavirus disease 2019 vaccine in pediatric post‐kidney transplantation

Ajlan

Aleid

Ali

et al. 2023

Clinical Transplantation

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Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infections and the resulting disease, coronavirus disease 2019 (COVID‐19), have spread to millions of persons worldwide. Many vaccines have been developed; however, their efficacy in pediatric solid organ transplant recipients is yet to be determined. Methods This is a prospective observational, non‐interventional single‐center study on the safety and efficacy of a COVID‐19 vaccine (BNT162b2) in pediatric kidney transplant recipients. The primary aim of this study was to evaluate immunogenicity according to SARS‐CoV‐2‐specific neutralizing antibody titer after two vaccine doses. The secondary aims were to investigate the safety of the vaccines, solicited local and systemic adverse reactions, incidence of COVID‐19 post‐vaccination, and effects on transplant graft function. Baseline investigations were conducted on pediatric renal transplant recipients, and recruited participants were advised to have the Comirnaty® mRNA vaccine according to protocol. Results A total of 48 patients (male, n = 31, 64.6%; female, n = 17, 35.4%), median age 14 [12–16] years were included, and all received two doses of the vaccine. The vaccine had a favorable safety and side‐effect profile. The S‐antibody titer of all patients ranged between .4 and 2,500 U/ml and was > 50 U/ml in 89% of the patients. No difference in the measured antibody immune response was noted between infected and uninfected children. No major side effects were reported. Conclusion The vaccine had a favorable safety profile in 12‐ to 15‐year‐old kidney transplant recipients, producing a greater measured antibody response than that in older transplant recipients.

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Profil épidémiologique et clinique des enfants atteints de la maladie à Corona Virus (COVID-19) au Centre de Traitement des Epidémies et Prévention des Infections (CTEPI) du CHU de Donka à Conakry

Cited by 8 publications

References 11 publications

Comparison of the Clinical Profile and Severity Factors of COVID-19 during the First 4 Waves in a Paediatric Population of Yaounde

Comparison of the Clinical Profile and Severity Factors of COVID-19 during the First 4 Waves in a Paediatric Population of Yaounde

Análisis de casos de COVID-19 y su fatalidad en mujeres menores de 19 años en México: un estudio transversal

Coronavirus disease 2019 vaccine in pediatric post‐kidney transplantation

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