Productivity losses due to premature mortality from cancer in Brazil, Russia, India, China, and South Africa (BRICS): A population-based comparison

Pearce, Alison; Sharp, Linda; Hanly, Paul; Барчук, Антон; Bray, Freddie; Cancela, Marianna de Camargo; Gupta, Prakash C.; Meheus, Filip; Qiao, You Lin; Sitas, Freddy; Wang, Shao Ming; Soerjomataram, Isabelle

doi:10.1016/j.canep.2017.12.013

Cited by 90 publications

(102 citation statements)

References 19 publications

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“…In 2018, 2.1 million women were newly diagnosed with breast cancer, and an estimated 626,679 women died due to breast cancer (2). Economically, breast cancer has been associated with increased healthcare costs and productivity losses (1)(2)(3)(4)(5). Among 27 European Union countries, breast cancer had the second largest share of overall cancer costs (12%), after lung cancer (15%) (e126 billion in 2009) (3).…”

Section: Introductionmentioning

confidence: 99%

“…Among 27 European Union countries, breast cancer had the second largest share of overall cancer costs (12%), after lung cancer (15%) (e126 billion in 2009) (3). Low-and middle-income countries have experienced disproportionately high amounts of productivity loss, incidence, and mortality of women due to breast cancer (1,3,4). In 2012, breast cancer was found to contribute to the highest productivity loss among women in all but one BRICS countries (Brazil, Russia, India, China, and South Africa), representing 0.33% of their gross domestic product (4).…”

Section: Introductionmentioning

confidence: 99%

“…Over 100 studies which observed the association between weight and fat distribution and the development of breast cancer have found that women who are overweight or obese have 30-50% higher risk of developing postmenopausal breast cancer compared to women with a normal body mass index (BMI) (1,5). An estimated 2.7 billion US dollars (USD) was spent on healthcare costs worldwide due to breast cancer that is attributed to physical inactivity (1,3,4).…”

Section: Introductionmentioning

confidence: 99%

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Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review

et al. 2020

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Background: In 2018, the global estimate of newly diagnosed breast cancer cases among women totaled 2.1 million. The economic and social burden that breast cancer places on societies has propelled research that analyzes the role of modifiable risk factors as the primary prevention methods. Healthy behavior changes, moderated alcohol intake, healthy body weight, and regular physical activity may decrease the risk of breast cancer among women. This review aimed to synthesize evidence on the cost-effectiveness of lifestyle-related interventions for the primary prevention of breast cancer in order to answer the question on whether implementing interventions focused on behavior changes are worth the value for money.Methods: A rapid review was performed using search terms developed by the research team. The articles were retrieved from MEDLINE and the Tufts Medical Center Cost-Effectiveness Analysis Registry, with an additional web search in Google and Google Scholar. Comparisons were performed on the cost-effectiveness ratio per quality-adjusted life-year between the interventions using a league table, and the likelihood of cost-effective interventions for breast cancer primary prevention was analyzed.Results: Six studies were selected. The median cost-effectiveness ratio (in 2018 USD) was $24,973, and 80% of the interventions had a ratio below the $50,000 threshold. The low-fat-diet program for postmenopausal women was cost-effective at a societal level, and the physical activity interventions, such as the Be Active Program in the UK, had the best cost saving results. A total of 11 of the 25 interventions ranked either as highly or very highly likely to be cost-effective for breast cancer primary preventions.Conclusion: Although the review had some limitations due to using only a few studies, it showed evidence that diet-related and physical-activity-related interventions for the primary prevention of breast cancer were cost-effective. Many of the cost-effective interventions aimed to reduce the risk of non-communicable diseases alongside breast cancer.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review

et al. 2020

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“…The authors of the study at the same time mark the problem of high and rising social inequalities in the BRICS countries, which may contribute to poor health outcomes there. Pearce et al (31) analyzed the productivity losses due to premature mortality from cancer in the five BRICS countries. The study findings are to some extent in line with the findings of our study, showing the highest level of economic loss caused by cancer-related deaths in relation to country GDP in South Africa followed by India.…”

Section: Discussionmentioning

confidence: 99%

Health System Outcomes in BRICS Countries and Their Association With the Economic Context

Romaniuk

Poznańska

Brukało

et al. 2020

Front. Public Health

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The aim of the article is to compare health system outcomes in the BRICS countries, assess the trends of their changes in 2000−2017, and verify whether they are in any way correlated with the economic context. The indicators considered were: nominal and per capita current health expenditure, government health expenditure, gross domestic product (GDP) per capita, GDP growth, unemployment, inflation, and composition of GDP. The study covered five countries of the BRICS group over a period of 18 years. We decided to characterize countries covered with a dataset of selected indicators describing population health status, namely: life expectancy at birth, level of immunization, infant mortality rate, maternal mortality ratio, and tuberculosis case detection rate. We constructed a unified synthetic measure depicting the performance of individual health systems in terms of their outcomes with a single numerical value. Descriptive statistical analysis of quantitative traits consisted of the arithmetic mean (xsr), standard deviation (SD), and, where needed, the median. The normality of the distribution of variables was tested with the Shapiro-Wilk test. Spearman's rho and Kendall tau rank coefficients were used for correlation analysis between measures. The correlation analyses have been supplemented with factor analysis. We found that the best results in terms of health care system performance were recorded in Russia, China, and Brazil. India and South Africa are noticeably worse. However, the entire group performs visibly worse than the developed countries. The health system outcomes appeared to correlate on a statistically significant scale with health expenditures per capita, governments involvement in health expenditures, GDP per capita, and industry share in GDP; however, these correlations are relatively weak, with the highest strength in the case of government's involvement in health expenditures and GDP per capita. Due to weak correlation with economic background, other factors may play a role in determining health system outcomes in BRICS countries. More research should be recommended to find them and determine to what extent and how exactly they affect health system outcomes.

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“…Увеличение заболеваемости КРР не только приводит к усилению нагрузки на медицинское сообщество, но и негативно сказывается на экономике страны. По приблизительным оценкам, в России в 2012 г. экономический ущерб от потерь здоровья больными злокачественными новообразованиями составил около 5 млрд долларов, или 0,25% от ВВП, а больными КРР -около 0,4 млрд долларов [5].…”

Section: Internal Medicineunclassified

Preparation for Introduction of a National Screening Program for Colorectal Cancer

Никонов¹,

Galkova²,

Kashin³

et al. 2019

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Productivity losses due to premature mortality from cancer in Brazil, Russia, India, China, and South Africa (BRICS): A population-based comparison

Cited by 90 publications

References 19 publications

Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review

Cost-Effectiveness of Lifestyle-Related Interventions for the Primary Prevention of Breast Cancer: A Rapid Review

Health System Outcomes in BRICS Countries and Their Association With the Economic Context

Preparation for Introduction of a National Screening Program for Colorectal Cancer

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