“…121 The core aim of this system is to improve drug efficacy and optimize pharmacokinetics and bioavailability while ensuring patient safety and convenience. A variety of polymeric materials that can be used as drug delivery matrices have been investigated, including biodegradable synthetic polymers such as poly(D,L-lactic acid-co-polyglycol) (PLGA), 122 as well as natural polymers such as collagen, 123 and alginate. 124 SF, a natural protein polymer, is considered an ideal biomedical material due to its unique set of physical and chemical properties.…”