Production performance, immune response and blood biochemical parameters in broiler chickens fed diet incorporated with prebiotics

Abstract

This experiment was conducted to identify the suitable replacer of broiler feed antibiotics with prebiotics (mannan oligosaccharides-MOS or fructooligosaccharide-FOS). Two hundred and forty (240)-day-old chicks were randomly divided into 30 groups (6 treatments x 5 replicates/treatment x 8 chicks/replicate). Six experimental diets T 1 , T 2 , T 3 , T 4 , T 5 and T 6 were formulated to contain an additional 0, antibiotic, that is, bacitracin methylene di-salicylate (BMD) @20 mg/kg, MOS (0.1% and 0.2%) and FOS (0.1% and 0.2%) respectively. Body weight gain was significantly (p < 0.05) increased in MOS-0.2% supplemented group at 0-21 d and 0-42 d of broiler chicken.Humoral and in vivo cell-mediated immune response were significantly improved (p < 0.05) in BMD, MOS @0.1% or 0.2% treated group. Significant (p < 0.05) increase was recorded in total protein (except 21 d), albumin and aspartate amino transferase (AST) and decrease (p < 0.05) in alanine amino transferase (except 42 d), cholesterol and uric acid concentration. The weight of breast, thigh, back, drumstick bursa of Fabricius and thymus were higher (p < 0.05) in the birds given the MOS @0.2% (T 4 ). It is concluded that MOS @0.2% may be suitable replacer of antibiotic growth promoter, and it has a beneficial effect on production performance, immune responses, blood biochemical parameters and cut up parts in broiler chickens. K E Y W O R D Sbroiler, carcass trait, immunity, Prebiotics, production performance

Injection of Raffinose Family Oligosaccharides at 12 Days of Egg Incubation Modulates the Gut Development and Resistance to Opportunistic Pathogens in Broiler Chickens

“…The increase of serum proteins and albumin not only reflects the status of protein synthesis, carbohydrate, and lipid metabolism [35], but according to Alonge et al, it also indicates the status of resistance and immune response in broilers [35]. In this study, the gradual increase in protein levels in the fattening period can be considered normal and related to the intensive growth of broilers, with similar results as in the other studies conducted on the Ross38 breed [34][35][36][37]. However, we observed a lower protein level in the serum of RFO-injected birds compared to the Control group at day 42 of rearing.…”

“…We found, that the in ovo delivered RFO reduced the levels of bilirubin, ALT and AST at the end of rearing. The low levels of these biochemical indices reflect a good condition of liver and muscles [36,39]. Such a hepatoprotective effect of the RFO prebiotics was also confirmed in other studies.…”

Growth performance, serum blood biochemistry, and intestinal properties of Arbor Acres Broiler fed diets containing mannan-riched fraction (MRF) and probiotic-enhanced liquid acidifier

“…The result may include the composition in the feed additive can prevent factors dead factors such as coccidian during the research. In the composition the Saccharomyces cerevisiae 1062, citric acid, sodium chloride, potassium chloride, acetic acid, sodium citrate, ethyl vanillin, zinc sulphate, iron sulphate, magnesium sulphate, dried Aspergillus niger fermentation extract, and dried Bacillus subtilis helps to stimulate immune modulation of broilers, Contrary to these findings, it was reported from study Biswas et al (2018) cannot help to reduce mortality in male broilers at 0-21 d and 0-42 d (3.38 vs 0.28 (control)) and (4.51 vs 1.69 (control)) because the experimental the broiler reared under stocking density stress (43 kg live weight per m 2 floor space) (Biswas et al, 2018).…”

“…The weight of bursa fabricius (percentage of live weight) using MOS 0.1% and 0.2% are not significance difference (P>0.05) (0.28 and 0.32 vs 0.29 (control)) at finisher periods of broiler (Biswas et al, 2018). The weight of liver, spleen and pancreas also are not significant difference (P>0.05) (Biswas et al, 2018). The exact explanation may due to prebiotic helps protect proliferating immature bursal B cells and thymic T lymphocytes from oxidative stress (Biswas et al, 2018).…”

“…The weight of bursa fabricius (percentage of live weight) using MOS 0.1% and 0.2% are not significance difference (P>0.05) (0.28 and 0.32 vs 0.29 (control)) at finisher periods of broiler (Biswas et al, 2018). The weight of liver, spleen and pancreas also are not significant difference (P>0.05) (Biswas et al, 2018).…”