Production of Spherical Beads by JetCutting

Prüße, Ulf; Dalluhn, J.; Breford, Jürgen; Vorlop, Klaus‐Dieter

doi:10.1002/1521-4125(200012)23:12<1105::aid-ceat1105>3.0.co;2-v

Cited by 51 publications

(17 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, low concentration of alginate (0.6% alginate with 0.3 M CaCl 2 ) was also applied to form beads (Jankowski, Zielinska, & Wysakowska, 1997). The major benefits of extrusion methods using alginate are that the viscosity of the matrix does not limit the production of the beads (Prüsse, Dalluhn, Breford, & Vorlop, 2000) and the biological core materials can be preceded at low temperatures without damaging their bioactivities. The survival rate of alginate encapsulated Bacillus cereus C1L was significantly higher than that of maltodextrin/gum arabic Bacillus cereus C1L (Table 3), but the final bacterial numbers of both capsules were around 10 6 -10 7 cfu/g.…”

Section: Discussionmentioning

confidence: 99%

Formulation of a novel antagonistic bacterium based biopesticide using microencapsulated techniques in fungal disease control

Chen¹,

Chen²,

Lin³

et al. 2013

JAS

View full text Add to dashboard Cite

Bacillus cereus strain C1L, screened from the rhizosphere of Lilium formosanum, prevents severe lily leaf blight. The purpose of this study was to formulate a new biopesticide by microencapsulating the C1L strain to enhance residual stability. In addition, since the viable cell number of Bacillus cereus C1L is an important factor affecting the biological effects of this fungicide, this study also used the response surface methodology and sequential quadratic programming methods to optimize the best formula for maximum viability of Bacillus cereus C1L microencapsulated by spray drying. Optimization results revealed that the strain could maintain 42% viability with 18.3% maltodextrin and 12.5% gum arabic as coating materials and spray drying at an outlet temperature of 73.5 ºC. A comparison with chemical pesticides showed that maneb was the most efficient disease inhibitor, followed by B. cereus C1L encapsulated by spray drying. The chemical pesticide probenazole and B. cereus C1L encapsulated by extrusion revealed no significant differences in disease control.

show abstract

Section: Discussionmentioning

confidence: 99%

Formulation of a novel antagonistic bacterium based biopesticide using microencapsulated techniques in fungal disease control

Chen¹,

Chen²,

Lin³

et al. 2013

JAS

View full text Add to dashboard Cite

show abstract

“…Automated lab-scale production of PVA/PEG-enzyme immobilisates ovitis when performed manually. The JetCutter as developed by Vorlop and coworkers [15] was successfully employed for the production of enzyme immobilisates. It is well suited for solutions with lower viscosity such as Ca-pectinate, Ca-alginate, chitosan, gelatin, and smaller bead diameters typically below 1 mm [15].…”

Section: Technical Reportmentioning

confidence: 99%

“…The JetCutter as developed by Vorlop and coworkers [15] was successfully employed for the production of enzyme immobilisates. It is well suited for solutions with lower viscosity such as Ca-pectinate, Ca-alginate, chitosan, gelatin, and smaller bead diameters typically below 1 mm [15]. However, losses of 5-20% induced by the shear from the cutting are inevitable [16].…”

Section: Technical Reportmentioning

confidence: 99%

Automated lab‐scale production of PVA/PEG‐enzyme immobilisates

Bieler¹,

Ansorge‐Schumacher²,

Greiner³

2010

Biotechnology Journal

View full text Add to dashboard Cite

Entrapment of biocatalysts by cryogelation is a gentle method to extend the scope of biocatalysis. To foster the use of this versatile method we devised an automated injector for the production of PVA/PEG beads. The device consists of a thermostated reservoir connected to a programmable injector nozzle and an agitated receiving bath for the droplets. This lab-scale production unit yields up to 1500 beads with immobilized enzyme per minute with a narrow size distribution and good roundness.

show abstract

“…A small part of the fluid (1-5%) can be lost during the cutting because of its adhesion to the wires and non-zero wire thickness [30]. The adjustment of the parameters to optimize the process along with reuse of the lost solution can lead to production yields close to 100%, making it a very efficient and easy-to-scale process [33].…”

Section: Introductionmentioning

confidence: 99%

Jet Cutting Technique for the Production of Chitosan Aerogel Microparticles Loaded with Vancomycin

et al. 2020

View full text Add to dashboard Cite

Biopolymer-based aerogels can be obtained by supercritical drying of wet gels and endowed with outstanding properties for biomedical applications. Namely, polysaccharide-based aerogels in the form of microparticles are of special interest for wound treatment and can also be loaded with bioactive agents to improve the healing process. However, the production of the precursor gel may be limited by the viscosity of the polysaccharide initial solution. The jet cutting technique is regarded as a suitable processing technique to overcome this problem. In this work, the technological combination of jet cutting and supercritical drying of gels was assessed to produce chitosan aerogel microparticles loaded with vancomycin HCl (antimicrobial agent) for wound healing purposes. The resulting aerogel formulation was evaluated in terms of morphology, textural properties, drug loading, and release profile. Aerogels were also tested for wound application in terms of exudate sorption capacity, antimicrobial activity, hemocompatibility, and cytocompatibility. Overall, the microparticles had excellent textural properties, absorbed high amounts of exudate, and controlled the release of vancomycin HCl, providing sustained antimicrobial activity.

show abstract

Production of Spherical Beads by JetCutting

Cited by 51 publications

References 9 publications

Formulation of a novel antagonistic bacterium based biopesticide using microencapsulated techniques in fungal disease control

Formulation of a novel antagonistic bacterium based biopesticide using microencapsulated techniques in fungal disease control

Automated lab‐scale production of PVA/PEG‐enzyme immobilisates

Jet Cutting Technique for the Production of Chitosan Aerogel Microparticles Loaded with Vancomycin

Contact Info

Product

Resources

About