Production of short ion pulses for TOF-RBS

Piel, N.; Becker, H.W.; Meijer, Jan; Schulte, W.H.; Rolfs, C.

doi:10.1016/s0168-9002(99)00759-7

Cited by 3 publications

(7 citation statements)

References 8 publications

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“…In fact, only a small portion of ions can be extracted into the mass spectrometer. Some techniques, such as internal ion compression (Piel et al, 1999) and ion storage (Chien, Michael, & Lubman, 1993), have been employed to achieve an effective detection of ions that enter a mass spectrometer, whereas less attention has been paid to the external accumulation of all analytes and ions during the ESI process and before entering the MS.…”

Section: Introductionmentioning

confidence: 99%

Naturally and externally pulsed electrospray

Wei

Wang

Zhou

et al. 2002

Mass Spectrometry Reviews

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The current studies on pulsation phenomena in electrospray ionization, and pulsed electrospray ionization (ESI) under external electrical control are reviewed. A number of investigations have shown that two types of pulsation processes exist: low-frequency fluctuation and high-frequency droplet-formation. The low-frequency pulsation is induced by an imbalance between the flow rate of the input sample to the Taylor cone and the feed rate of the output solution to the liquid filament. The high-frequency pulsation mainly results from the initial droplet formation process, and is modulated by the low-frequency pulsation. The fundamental and experimental sections of these two pulsations are discussed. Experimental results also show that low and high pulsations can both be controlled electrically to create a pulsed ESI so that high sensitivity and an enhanced S/N ratio can be achieved. However, the co-ordination of the synchronization between a natural pulsation and a pulsed ESI, as well as its application to mass spectrometer (MS) analysis, demands further research.

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Section: Introductionmentioning

confidence: 99%

Naturally and externally pulsed electrospray

Wei

Wang

Zhou

et al. 2002

Mass Spectrometry Reviews

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“…The start signal can be provided by either secondary electrons emitted from a thin foil situated in the flight path or from the pulsing system while the stop signal is derived from a detector. Piel et al 5 have achieved a depth resolution of 0.8 nm with 100 keV pulsed 4 He ϩ ions scattered off a sample at angle ϭ160°and a flight path of 39.6 cm. For the past decade, the TOF-RBS at medium incident energy has gained increasing interest.…”

Section: Introductionmentioning

confidence: 99%

“…For the past decade, the TOF-RBS at medium incident energy has gained increasing interest. [5][6][7][8][9] The RBS spectrometry with typical incident energies between 100 and 500 keV and ions ranging from 4 He to 12 C is generally known as low-or mediumenergy ion scattering spectroscopy.…”

Section: Introductionmentioning

confidence: 99%

Characterization of a compact filament-driven multicusp ion source for low energy time-of-flight Rutherford backscattering spectrometry application

Dangtip

Junphong

Ano

et al. 2004

Review of Scientific Instruments

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Because of the limited pulse height energy resolution of a detector, conventional Rutherford backscattering spectrometry ͑RBS͒ requires an energy of the incident ␣ particle to be in the MeV region. At Chiang Mai University we have researched the possibility of utilizing a 280 keV nanosecond pulse of helium ions for RBS applications. We have chosen a compact filament-driven multicusp ion source of 2.6 cm in diameter and 8 cm in length being investigated for the time-of-flight RBS applications. In this article, we present the general ion source performance using helium, nitrogen, and argon for generating the discharge plasma. The general ion source characteristics have been measured and analyzed. The measurements also include the extractable ion current and the ion beam emittance. We have performed beam extraction calculations with a computer simulation code KOBRA. Results of the measurements and calculations will be presented and discussed.

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“…This is because such techniques have rather low flow rates of microliters to submicroliters per minute. − Even if all the analytes in the effluent were ionized, the sensitivity of ESI-MS could still be a problem mainly due to the wasting of ions as mentioned above, such as in capillary isoelectric focusing (CIEF)-MS, which has been studied as a promising new technique for proteomics recently . Therefore, to generate a pulsed ion beam with little wasting of ions has attracted a number of research efforts. − …”

mentioning

confidence: 99%

“…Prior to entering the TOF-MS, the ions are expected to be accumulated and then repelled out for TOF-MS analysis by applying the ion trap. On-beam compression has also been used to accumulate ions during the beam modulation . With a proper setting of ion optics in the beam trajectory, incoming ions can be compressed and accumulated and then be gated to the TOF-MS.…”

mentioning

confidence: 99%

Pulsed Electrospray for Mass Spectrometry

Zhou

Wang

et al. 2001

Anal. Chem.

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Pulsed electrospray has been developed and been reported for the first time. This new technique is based on the principle of pulsed ion sources, combined with the conventional electrospray. The pulsed ion spray was realized by a homemade pulsed HV circuit and was monitored by a digital microscope and an oscilloscope. Results show that the pulsed ESI device can be operated under proper conditions for a clear on-and-off spray process and that the device was kept in good electric contact for electrospray when pulsed HV was on. A pulsed ion current and pulsed mass spectra can be achieved with this pulsed ESI device. Furthermore, it has been noted that, under the same conditions (i.e., shape and size of sprayer tip, distance from sprayer tip to sampling nozzle, and other parameters for mass spectrometer), stable electrospray could be obtained for lower flow rates with a pulsed spray device. This experimental fact indicates the possible reduction in the total sample consumed could be realized by exploiting this novel design.

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Production of short ion pulses for TOF-RBS

Cited by 3 publications

References 8 publications

Naturally and externally pulsed electrospray

Naturally and externally pulsed electrospray

Characterization of a compact filament-driven multicusp ion source for low energy time-of-flight Rutherford backscattering spectrometry application

Pulsed Electrospray for Mass Spectrometry

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