“…Thus, C. glutamicum was engineered for production of carboxylic acids such as pyruvate (Wieschalka et al, 2012) and succinate (Litsanov et al, 2012), oxoacids such as 2-ketoisovalerate (Krause et al, 2010) and 2-ketoisocaproate (Bückle-Vallant et al, 2014), alcohols such as ethanol (Inui et al, 2004a), isobutanol (Blombach et al, 2011), and n -propanol (Siebert and Wendisch, 2015), polymers such as polyhydroxyalkanoate (Ma et al, 2018). As industrial amino acid producer C. glutamicum is ideal for fermentative production of various other nitrogenous compounds such as the cyclic amino acid pipecolic acid (Pérez-García et al, 2016), the ω-amino acids γ-aminobutyrate (Kim et al, 2013; Jorge et al, 2016; Pérez-García et al, 2016) and 5-aminovalerate (Rohles et al, 2016; Jorge et al, 2017), the diamines putrescine (Schneider and Wendisch, 2010) and cadaverine (Tateno et al, 2009; Kim et al, 2018) and alkylated and hydroxylated amino acids such as N -methylalanine (Mindt et al, 2018) and 5-hydroxy-isoleucine (Wendisch, 2019). Noteworthy, several excellent C. glutamicum producer strains have been developed for production of muconic acid (Becker et al, 2018), phenylpropanoids (Kallscheuer and Marienhagen, 2018), para -hydroxybenzoic acid (Purwanto et al, 2018), and protocatechuate (Wendisch et al, 2016; Lee and Wendisch, 2017).…”