Production of Hydroxyl Radical via the Activation of Hydrogen Peroxide by Hydroxylamine

Chen, Liwei; Li, Xuchun; Zhang, Jing; Fang, Jingyun; Huang, Yu‐Chen; Wang, Ping; Ma, Jun

doi:10.1021/acs.est.5b00483

Cited by 142 publications

(98 citation statements)

References 41 publications

(101 reference statements)

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“…Chen et al determined that when the time of existence of • OH was extended from 24 to 96 h, the oxidation efficiency of benzoic acid (BA) increased from 6 to 19% . Vicente et al reported that when 20 mM citric acid was used as a chelating agent, 80–90% of the organic pollutant, 2,4‐DMP, was removed, and the removal efficiency (60%) increased by 20–30% compared with the removal efficiency without a chelating agent .…”

Section: Resultsmentioning

confidence: 99%

The Frequent Effects of Hydroxyl Radicals on the Oxidation of Crude Oil in Soil

Cao

Zhang

et al. 2018

CLEAN Soil Air Water

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The characteristics of hydroxyl radicals (•OH) frequently produced in the Fenton process and the effects of these radicals on the oxidation of hydrophobic total petroleum hydrocarbons (TPH) in soil are investigated. Twelve groups of Fenton oxidation experiments are conducted using two kinds of crude‐oil‐contaminated soil samples (S1 and S2) with different soil organic matter (SOM) contents. The results show that the decrease of TPH increases by 6774 mg kg−1 (S1) and 5875 mg kg−1 (S2) by using the frequent •OH (•OHf). These results are two times the results obtained by using the single •OH (•OHs) (S1: 3410 mg kg−1, S2: 2918 mg kg−1). The decrease of hydrophobic long‐chain alkanes C21–C30 is greatly improved by using the •OHf, that is, oxidation of 1557–3011 mg kg−1 in soil S1 and 1371–2532 mg kg−1 in soil S2. Moreover, the C21–C30 alkanes in soil S1 with low SOM (3.89%) are more degraded after oxidation. The residual non‐aqueous phase liquid (NAPL) TPH content by using the •OHf (266–1200 mg kg−1) is much lower than that by using the •OHs (2519–4070 mg kg−1). The residual of the NAPL TPH by using the •OHf is 11–29% of the residual by using the •OHs. This result indicates that residual NAPL TPH is reduced by using the •OHf, and the TPH contents in the two soil samples are efficiently oxidized.

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Section: Resultsmentioning

confidence: 99%

The Frequent Effects of Hydroxyl Radicals on the Oxidation of Crude Oil in Soil

Cao

Zhang

et al. 2018

CLEAN Soil Air Water

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“…Enzymatic antioxidants include superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), thioredoxin (TRX), peroxiredoxin (PRX) and glutathione transferase (GST) [61]. The spontaneous or enzymatic dismutation of superoxide by SOD produces H 2 O 2 , oxygen (O 2 ) and water (H 2 O); however, H 2 O 2 can be also be reduced to hydroxyl radicals (HO) [62]. There are three different isoforms of SOD; manganese (Mn)-SOD (SOD2) which is mainly located in the mitochondria, SOD1 in the cytoplasm and SOD3 in the extracellular space [58].…”

Section: Sources Of Reactive Oxygen Speciesmentioning

confidence: 99%

Reactive Oxygen Species in Acute Lymphoblastic Leukaemia: Reducing Radicals to Refine Responses

et al. 2021

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Acute lymphoblastic leukaemia (ALL) is the most common cancer diagnosed in children and adolescents. Approximately 70% of patients survive >5-years following diagnosis, however, for those that fail upfront therapies, survival is poor. Reactive oxygen species (ROS) are elevated in a range of cancers and are emerging as significant contributors to the leukaemogenesis of ALL. ROS modulate the function of signalling proteins through oxidation of cysteine residues, as well as promote genomic instability by damaging DNA, to promote chemotherapy resistance. Current therapeutic approaches exploit the pro-oxidant intracellular environment of malignant B and T lymphoblasts to cause irreversible DNA damage and cell death, however these strategies impact normal haematopoiesis and lead to long lasting side-effects. Therapies suppressing ROS production, especially those targeting ROS producing enzymes such as the NADPH oxidases (NOXs), are emerging alternatives to treat cancers and may be exploited to improve the ALL treatment. Here, we discuss the roles that ROS play in normal haematopoiesis and in ALL. We explore the molecular mechanisms underpinning overproduction of ROS in ALL, and their roles in disease progression and drug resistance. Finally, we examine strategies to target ROS production, with a specific focus on the NOX enzymes, to improve the treatment of ALL.

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“…S3), was regarded as an oxidation product of MeOH, and it could be continually mineralized when considering that the theoretical organic carbon of CT only contributed to 1.6 mg L −1 of TOC in this process. Based on the literature [26], after a series of complex reactions with O 2 , H 2 O 2 and OH • , HCHO would be transformed into HCOOH, which has been confirmed to produce CO 2 •− under the aid of OH • [23,27].…”

Section: Mechanism Of Ct Reduction In the Cao 2 /Fe(ii)/meoh Systemmentioning

confidence: 99%

Mechanism of carbon tetrachloride reduction in ferrous ion activated calcium peroxide system in the presence of methanol

Tang

Jiang

Lyu

et al. 2019

Chemical Engineering Journal

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This study investigated the reductive initiation for the depletion of highly oxidized/perhalogenated pollutants, specifically the degradation of carbon tetrachloride (CT) was induced by adding methanol (MeOH) into a ferrous ion (Fe(II)) activated calcium peroxide (CaO 2 ) system. The results indicated that CT could be completely degraded within 20 min at CaO 2 /Fe(II)/MeOH/CT molar ratio of 30/40/10/1 in this system. Scavenging tests suggested that both superoxide radical anion (O 2•− ) and carbon dioxide radical anion (CO 2 •− ) were predominant reactive species responsible for CT destruction. Hydroxymethyl radicals ( • CH 2 OH), an intermediate in the transformation of MeOH, could also initiate CT degradation by reducing C-Cl bond. GC/MS analysis identified CHCl 3 , C 2 Cl 4 , and C 2 Cl 6 as the intermediates accompanied by CT destruction, and a reduction mechanism for CT degradation was proposed accordingly. In addition, the impact of solution matrix and initial solution pH were evaluated, and the results showed that Cl − , NO 3 − , and HCO 3 − had adverse effects on CT degradation. Moreover, the alkaline condition was unfavorable to CT depletion. In conclusion, the results obtained in the actual groundwater tests encouragingly demonstrated that the CaO2/Fe(II)/MeOH process is a highly promising technique for the remediation of CT-contaminated groundwater.

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Production of Hydroxyl Radical via the Activation of Hydrogen Peroxide by Hydroxylamine

Cited by 142 publications

References 41 publications

The Frequent Effects of Hydroxyl Radicals on the Oxidation of Crude Oil in Soil

The Frequent Effects of Hydroxyl Radicals on the Oxidation of Crude Oil in Soil

Reactive Oxygen Species in Acute Lymphoblastic Leukaemia: Reducing Radicals to Refine Responses

Mechanism of carbon tetrachloride reduction in ferrous ion activated calcium peroxide system in the presence of methanol

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