Production of Hyaluronic Acid from Molasses by Streptococcus thermophilus TISTR 458

Saraphanchotiwitthaya, Aurasorn; Sripalakit, Pattana

doi:10.48048/tis.2022.2192

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…In this way, an HA yield of 30 g/L was successfully attained [ 88 ]. Another strategy showed that as an alternative to glucose, molasses could be used as a carbon source in the fermentation medium of S. zooepidemicus [ 89 ]. Indeed, the presence of this alternative and cheaper sugar allowed an increase in the yield of the HA up to 0.2 g/L compared to standard conditions (43 mg/L) [ 89 ].…”

Section: Ha Fermentation Process In Engineered Host Microorganismsmentioning

confidence: 99%

“…Another strategy showed that as an alternative to glucose, molasses could be used as a carbon source in the fermentation medium of S. zooepidemicus [ 89 ]. Indeed, the presence of this alternative and cheaper sugar allowed an increase in the yield of the HA up to 0.2 g/L compared to standard conditions (43 mg/L) [ 89 ]. In addition to the pH, the incubation temperature, agitation speed, soil composition, and size of inoculum are key parameters of the fermentation process that affect the yield of the final product.…”

Section: Ha Fermentation Process In Engineered Host Microorganismsmentioning

confidence: 99%

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Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications—A Comprehensive Review

Iaconisi,

Lunetti,

Gallo

et al. 2023

IJMS

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Hyaluronic acid (HA) is a glycosaminoglycan widely distributed in the human body, especially in body fluids and the extracellular matrix of tissues. It plays a crucial role not only in maintaining tissue hydration but also in cellular processes such as proliferation, differentiation, and the inflammatory response. HA has demonstrated its efficacy as a powerful bioactive molecule not only for skin antiaging but also in atherosclerosis, cancer, and other pathological conditions. Due to its biocompatibility, biodegradability, non-toxicity, and non-immunogenicity, several HA-based biomedical products have been developed. There is an increasing focus on optimizing HA production processes to achieve high-quality, efficient, and cost-effective products. This review discusses HA’s structure, properties, and production through microbial fermentation. Furthermore, it highlights the bioactive applications of HA in emerging sectors of biomedicine.

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Section: Ha Fermentation Process In Engineered Host Microorganismsmentioning

confidence: 99%

Section: Ha Fermentation Process In Engineered Host Microorganismsmentioning

confidence: 99%

Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications—A Comprehensive Review

Iaconisi,

Lunetti,

Gallo

et al. 2023

IJMS

View full text Add to dashboard Cite

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Hyaluronic acid-based nanofibers: Electrospun synthesis and their medical applications; recent developments and future perspective

et al. 2022

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Hyaluronan is a biodegradable, biopolymer that represents a major part of the extracellular matrix and has the potential to be fabricated in a fibrous form conjugated with other polymers via electrospinning. Unique physicochemical features such as viscoelasticity, conductivity, and biological activity mainly affected by molecular weight attracted the attention of biomedical researchers to utilize hyaluronan for designing novel HA-based nano-devices. Particularly HA-based nanofibers get focused on a diverse range of applications in medical like tissue implants for regeneration of damaged tissue or organ repair, wound dressings, and drug delivery carriers to treat various disorders. Currently, electrospinning represents an effective available method for designing highly porous, 3D, HA-based nanofibers with features similar to that of the extra-cellular matrix making them a promising candidate for designing advanced regenerative medicines. This review highlights the structural and physicochemical features of HA, recently cited protocols in literature for HA production via microbial fermentation with particular focus on electrospun fabrication of HA-based nanofibers and parameters affecting its synthesis, current progress in medical applications of these electrospun HA-based nanofibers, their limitations and future perspective about the potential of these HA-based nanofibers in medical field.

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Synbiotics and Their Antioxidant Properties, Mechanisms, and Benefits on Human and Animal Health: A Narrative Review

et al. 2022

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Antioxidants are often associated with a variety of anti-aging compounds that can ensure human and animal health longevity. Foods and diet supplements from animals and plants are the common exogenous sources of antioxidants. However, microbial-based products, including probiotics and their derivatives, have been recognized for their antioxidant properties through numerous studies and clinical trials. While the number of publications on probiotic antioxidant capacities and action mechanisms is expanding, that of synbiotics combining probiotics with prebiotics is still emerging. Here, the antioxidant metabolites and properties of synbiotics, their modes of action, and their different effects on human and animal health are reviewed and discussed. Synbiotics can generate almost unlimited possibilities of antioxidant compounds, which may have superior performance compared to those of their components through additive or complementary effects, and especially by synergistic actions. Either combined with antioxidant prebiotics or not, probiotics can convert these substrates to generate antioxidant compounds with superior activities. Such synbiotic-based new routes for supplying natural antioxidants appear relevant and promising in human and animal health prevention and treatment. A better understanding of various component interactions within synbiotics is key to generating a higher quality, quantity, and bioavailability of antioxidants from these biotic sources.

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Production of Hyaluronic Acid from Molasses by Streptococcus thermophilus TISTR 458

Cited by 4 publications

References 16 publications

Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications—A Comprehensive Review

Hyaluronic Acid: A Powerful Biomolecule with Wide-Ranging Applications—A Comprehensive Review

Hyaluronic acid-based nanofibers: Electrospun synthesis and their medical applications; recent developments and future perspective

Synbiotics and Their Antioxidant Properties, Mechanisms, and Benefits on Human and Animal Health: A Narrative Review

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