Production of gaseous nitrogen in human steady-state conditions

Cissik, John H.; Johnson, Robert E.; Rokosch, D. K.

doi:10.1152/jappl.1972.32.2.155

Cited by 27 publications

(15 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results appear to be similar to those of the other investigators (9,14,20,22) recently attempting to reproduce the work of Cissik and Dudka (2,9), but our findings renewed confidence in the Haldane assumption.. In these studies good agreement between Haldane and direct computations of VO, has been obtained.…”

Section: Resultssupporting

confidence: 90%

“…No physiological significance should be attributed to this difference.A: 600 kp*m/min the Haldane transformation resul!ed in a 1.8% underestimation of VOz(Table 5). With essentially no difference in VC02, and a relatively larger V02 value, the indirect calculation resulted in a statistically significantly greater R. This difference is, however, in the opposite direction from that reported by Cissik and others(2).Downloaded by [Indiana University Libraries] at 23:00 16 March 2015Table 3-90,, VCO,, R, V1N,, and V& Values at Rest…”

mentioning

confidence: 68%

See 1 more Smart Citation

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O₂and [Vdot]CO₂

Musch

Brooks

1976

Research Quarterly. American Alliance for Health, Physical Educ

View full text Add to dashboard Cite

Section: Resultssupporting

confidence: 90%

mentioning

confidence: 68%

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O₂and [Vdot]CO₂

Musch

Brooks

1976

Research Quarterly. American Alliance for Health, Physical Educ

View full text Add to dashboard Cite

“…Their estimates for N 2 elimination rates have been confirmed by a recent study [14]. Other studies have suggested nonzero N 2 balance in a variety of clinical and metabolic states [15][16][17][18]. Wilmore found that this did not significantly influence measurement of _ V O 2 during exercise, primarily due to the high levels of _ V O 2 achieved [19].…”

Section: Discussionmentioning

confidence: 71%

Measured pulmonary oxygen consumption: difference between systemic oxygen uptake measured by the reverse Fick method and indirect calorimetry in cardiac surgery

Peyton

Robinson

2005

Anaesthesia

View full text Add to dashboard Cite

SummaryMeasurement of oxygen uptake by indirect calorimetry was compared with the reverse Fick method in a series of patients undergoing cardiac surgery. Oxygen uptake measurements for indirect calorimetry were made using a calibrated measurement system utilizing the Haldane transformation in a simple semiclosed breathing system based upon a modified Bain circuit. Pulmonary blood flow for the reverse Fick method was measured using bolus thermodilution. The results were (mean [standard deviation]): indirect calorimetry 167[26] ml.min

show abstract

“…A significant part of the difference in the N balance is made up of N 2 gas (45,47,82) . A possible source is the reaction of nitrite and free amino acids, which in an acidic medium yield N 2 gas and 2-hydroxyacids (83) ; this reaction has been described to occur in the stomach lumen (84) .…”

Section: Nitrite and Other Forms Of Nitrogen Excretionmentioning

confidence: 99%

The problem of nitrogen disposal in the obese

Alemany

2012

Nutr. Res. Rev.

View full text Add to dashboard Cite

Amino-N is preserved because of the scarcity and nutritional importance of protein. Excretion requires its conversion to ammonia, later incorporated into urea. Under conditions of excess dietary energy, the body cannot easily dispose of the excess amino-N against the evolutively adapted schemes that prevent its wastage; thus ammonia and glutamine formation (and urea excretion) are decreased. High lipid (and energy) availability limits the utilisation of glucose, and high glucose spares the production of ammonium from amino acids, limiting the synthesis of glutamine and its utilisation by the intestine and kidney. The amino acid composition of the diet affects the production of ammonium depending on its composition and the individual amino acid catabolic pathways. Surplus amino acids enhance protein synthesis and growth, and the synthesis of non-protein-N-containing compounds. But these outlets are not enough; consequently, less-conventional mechanisms are activated, such as increased synthesis of NO z followed by higher nitrite (and nitrate) excretion and changes in the microbiota. There is also a significant production of N 2 gas, through unknown mechanisms. Health consequences of amino-N surplus are difficult to fathom because of the sparse data available, but it can be speculated that the effects may be negative, largely because the fundamental N homeostasis is stretched out of normalcy, forcing the N removal through pathways unprepared for that task. The unreliable results of hyperproteic diets, and part of the dysregulation found in the metabolic syndrome may be an unwanted consequence of this N disposal conflict.

show abstract

Production of gaseous nitrogen in human steady-state conditions

Cited by 27 publications

References 0 publications

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O₂and [Vdot]CO₂

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O₂and [Vdot]CO₂

Measured pulmonary oxygen consumption: difference between systemic oxygen uptake measured by the reverse Fick method and indirect calorimetry in cardiac surgery

The problem of nitrogen disposal in the obese

Contact Info

Product

Resources

About

Production of gaseous nitrogen in human steady-state conditions

Cited by 27 publications

References 0 publications

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O2and [Vdot]CO2

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O2and [Vdot]CO2

Measured pulmonary oxygen consumption: difference between systemic oxygen uptake measured by the reverse Fick method and indirect calorimetry in cardiac surgery

The problem of nitrogen disposal in the obese

Contact Info

Product

Resources

About

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O₂and [Vdot]CO₂

Effect of Diet and Metabolic Rate on Open Circuit Calculations of [Vdot]O₂and [Vdot]CO₂