Production of Fermented Beverages: Shedding Light on Indian Culture and Traditions

Clinical features and mechanistic insights into drug repurposing for combating COVID-19

“…Traditional plants have an age old history of being used for the treatment of various diseases (Asrani et al, 2019). Lanhuaqingwen (LH), is a Chinese traditional medicine made up of 13 herbs.…”

Tamoxifen for hepatocellular carcinoma

“…The burden of liver cancer in 2017 was 20.8 million disability-adjusted life-years (DALYs) (95% uncertainty interval 19.9 million to 21.8 million) (Fitzmaurice 2019). HCC is the sixth most common type of cancer (Asrani 2019;Fitzmaurice 2019). It is the fourth leading cause of cancer-related deaths worldwide (i.e.…”

“…It is the fourth leading cause of cancer-related deaths worldwide (i.e. 810,000 deaths in 2015 (Asrani 2019)), albeit with substantial variation in age, sex, and geographic distribution (Bray 2018). According to the GLOBOCAN estimate in 2018, the agestandardised incidences were highest in Eastern Asia, followed by South-Eastern Asia and Northern Africa (Petrick 2016;Bray 2018).…”

“…Cirrhosis is an important risk factor for HCC, and among all aetiologies of cirrhosis, the risk is higher in people with chronic viral hepatitis. Overall, one-third of people with cirrhosis will develop HCC during their lifetime (EASL 2018), while around 40% of each HCC is attributed to HBV or HCV infections, 11% to alcohol consumption, and 10% to other nonspecific causes (Petrick 2016;Asrani 2019). An epidemiologic study reported that the yearly cumulative incidence of HCC was 2.6% in the non-alcoholic fatty liver disease (NAFLD) group compared to 4% in the HCV group (Ascha 2010;Kawamura 2012).…”