Production of Amino and Organic Acids from Protein Using Sub-Critical Water Technology

Abdelmoez, Wael; Yoshida, Hiroyuki

doi:10.1515/ijcre-2013-0017

Cited by 29 publications

(28 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Basic hydrolysis of the peptide bond produces a carboxylate ion instead of a carboxylic acid, therefore not affecting the amino groups. Because amino acids are high value molecules for the food and pharmaceutical industries, the majority of studies focus on the recovery of these building blocks from protein rich resources or model proteins: meat and fish processing wastes [73 75, 174 176], cereal wastes [177] or model compounds such as silk protein [172], soy protein [178] and bovine serum albumin [120,179,180].…”

Section: °C 310°c 320°c 330°cmentioning

confidence: 99%

Energy valorisation of food processing residues and model compounds by hydrothermal liquefaction

Déniel

Haarlemmer

Roubaud

et al. 2016

Renewable and Sustainable Energy Reviews

150

View full text Add to dashboard Cite

International audienceThe upcoming depletion of fossil fuels calls for the development of alternative energies produced from renewable resources. Particularly, energy valorisation of agriculture and food processing wastes is one of the most promising tools for renewable energy production. The amount of food wastes is rapidly increasing due to urbanisation, industrialisation and population growth worldwide. They consequently represent a widely available resource, and their use as a raw material allows reducing the environmental cost associated with their disposal. These resources usually have high moisture content, making dry valorisation processes unattractive because of a costly drying step prior to conversion. Hydrothermal processes are conversely particularly well suited for the valorisation of wet organic wastes in an economical way, since they use water as the reaction medium. More specifically, liquid fuels can be produced using hydrothermal liquefaction (HTL). The process converts wet biomass into a crude-like oil with higher heating values up to 40 MJ/kg using subcritical water (T=250-370 degrees C, P=10-30 MPa). Though this is an active research area, the mechanisms of hydrothermal liquefaction still remain unclear today. Some processes have already been developed at the pilot scale for valorising food processing wastes. However, the development of HTL processes at industrial scales is facing technological and economic challenges. This paper discusses the two main issues to address for development of the process at large scales. On the one hand, hydrothermal conversion of food processing residues and model compounds is necessary to better understand the fundamentals of hydrothermal liquefaction. As well, technological and process integration issues have to be addressed to ensure economic viability of commercial HTL processes

show abstract

Section: °C 310°c 320°c 330°cmentioning

confidence: 99%

Energy valorisation of food processing residues and model compounds by hydrothermal liquefaction

Déniel

Haarlemmer

Roubaud

et al. 2016

Renewable and Sustainable Energy Reviews

150

View full text Add to dashboard Cite

show abstract

“…Under subcritical thermohydrolytic conditions, the intermediate polypeptide chains produced as a result of hydrolysis of proteins undergo further hydrolysis to amino acids. Reportedly, the amino acids are highly labile under subcritical hydrothermal conditions, and undergo further degradation resulting in short chain fatty acids [ 60 , 61 , 62 , 63 ]. In agreement with the further degradation of amino acids at higher hydrolysis temperatures, Asaduzzman and Chung found that the amino acid yields also decreased with increasing temperature [ 46 ].…”

Section: Protein Extraction and Recovery From Proteinaceous Biomasmentioning

confidence: 99%

“…As evident from the molecular size distribution of peptides recovered from two different hydrolyzates ( Figure 1 ), hydrolysis under alkaline conditions carried out extensive breakage of amide linkages producing a larger proportion of relatively smaller chain peptides and free amino acids. A plausible reason for the observed lower yield of proteinaceous materials under alkaline hydrolysis could be the severe breakage of amide linkages resulting in increased amounts of free amino acids in the hydrolyzate; further decomposition of the resulting amino acids through a mechanism similar to the deamination of proteins was observed through thermal hydrolysis of bovine serum albumin (BSA) [ 61 , 62 , 63 ].…”

Section: Protein Extraction and Recovery From Proteinaceous Biomasmentioning

confidence: 99%

Utilization of Slaughterhouse Waste in Value-Added Applications: Recent Advances in the Development of Wood Adhesives

2018

View full text Add to dashboard Cite

Globally, slaughterhouses generate large volumes of animal byproducts. While these byproducts are an important resource of industrial protein that could potentially be utilized in various value-added applications, they are currently either underutilized in high-value applications or being used for production of relatively low-value products such as animal feed and pet food. Furthermore, some of the byproducts of animal slaughtering cannot enter food and feed chains and thus their disposal possesses a serious environmental concern. An innovative utilization of the proteinaceous waste generated by slaughterhouses comprises of waste processing to extract proteins, which are then incorporated into industrial processes to produce value-added bio-based products. In this report, we review the current processes for extraction of protein from proteinaceous waste of slaughterhouses, and utilization of the recovered protein in the development of protein-based wood adhesives.

show abstract

“…Although water is ionized via the collision of water molecules at ordinary temperatures and pressures, ionization progresses as the temperature increases. As a result, the concentration of hydroxide ions (OHˉ), which are capable of hydrolyzing the peptide bonds of proteins, as well as lipids and carbohydrates, to produce free amino acids [ 19 ], fatty acids [ 20 ], and glucose [ 21 ], respectively, is markedly higher in SCW than in normal water. Notably, the optimal hydrolytic activity of SCW occurs at approximately 250°C [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrPSc but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions

et al. 2015

View full text Add to dashboard Cite

The global outbreak of bovine spongiform encephalopathy (BSE) has been attributed to the recycling of contaminated meat and bone meals (MBMs) as feed supplements. The use of MBMs has been prohibited in many countries; however, the development of a method for inactivating BSE prions could enable the efficient and safe use of these products as an organic resource. Subcritical water (SCW), which is water heated under pressure to maintain a liquid state at temperatures below the critical temperature (374°C), exhibits strong hydrolytic activity against organic compounds. In this study, we examined the residual in vitro seeding activity of protease-resistant prion protein (PrPSc) and the infectivity of BSE prions after SCW treatments. Spinal cord homogenates prepared from BSE-infected cows were treated with SCW at 230–280°C for 5–7.5 min and used to intracerebrally inoculate transgenic mice overexpressing bovine prion protein. Serial protein misfolding cyclic amplification (sPMCA) analysis detected no PrPSc in the SCW-treated homogenates, and the mice treated with these samples survived for more than 700 days without any signs of disease. However, sPMCA analyses detected PrPSc accumulation in the brains of all inoculated mice. Furthermore, secondary passage mice, which inoculated with brain homogenates derived from a western blotting (WB)-positive primary passage mouse, died after an average of 240 days, similar to mice inoculated with untreated BSE-infected spinal cord homogenates. The PrPSc accumulation and vacuolation typically observed in the brains of BSE-infected mice were confirmed in these secondary passage mice, suggesting that the BSE prions maintained their infectivity after SCW treatment. One late-onset case, as well as asymptomatic but sPMCA-positive cases, were also recognized in secondary passage mice inoculated with brain homogenates from WB-negative but sPMCA-positive primary passage mice. These results indicated that SCW-mediated hydrolysis was insufficient to eliminate the infectivity of BSE prions under the conditions tested.

show abstract

Production of Amino and Organic Acids from Protein Using Sub-Critical Water Technology

Cited by 29 publications

References 7 publications

Energy valorisation of food processing residues and model compounds by hydrothermal liquefaction

Energy valorisation of food processing residues and model compounds by hydrothermal liquefaction

Utilization of Slaughterhouse Waste in Value-Added Applications: Recent Advances in the Development of Wood Adhesives

Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrPSc but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions

Contact Info

Product

Resources

About