Production method of no-carrier-added186Re

Shigeta, Naotaka; Matsuoka, Hiromitsu; Osa, A.; Koizumi, M.; Izumo, Mishiroku; Kobayashi, Katsutoshi; Hashimoto, Katsuhiro; Sekine, T.; Lambrecht, Richard M.

doi:10.1007/bf02040553

Cited by 56 publications

(36 citation statements)

References 3 publications

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“…6 together with the available experimental values and theoretical data taken from ALICE-IPPE code [17]. We found a very good agreement with the data reported by Lapi et al [14], Tarkanyi et al [16], Szelecsenyi et al [18], and Shigeta et al [8] in the investigated energy region. The data reported by Zhang et al…”

Section: Cross-sections Of Residual Radioisotopes Of Rheniumsupporting

confidence: 90%

“…Several investigations [7][8][9] were carried out for the production of high specific activity 186 Re radionuclide in no carrier added (NCA) form by proton bombardment on enriched tungsten targets using cyclotron, but large discrepancies are found among them. On a practical level, it is very difficult to estimate the causes of discrepancies among the data sets.…”

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confidence: 99%

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Excitation functions of proton induced nuclear reactions on natW up to 40MeV

Khandaker

Uddin

Kim

et al. 2008

Nuclear Instruments and Methods in Physics Research Section B:

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Excitation functions for the production of the 181,182m,182g,183,184g,186 Re and 183,184 Ta radionuclides from proton bombardment on natural tungsten were measured using the stacked-foil Re has remarkable applications in the field of nuclear medicine, whereas the data of 183,184g Re and 183 Ta have potential applications in thin layer activation analysis and biomedical tracer studies, respectively.

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Section: Cross-sections Of Residual Radioisotopes Of Rheniumsupporting

confidence: 90%

mentioning

confidence: 99%

Excitation functions of proton induced nuclear reactions on natW up to 40MeV

Khandaker

Uddin

Kim

et al. 2008

Nuclear Instruments and Methods in Physics Research Section B:

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“…In their experiment the energy was degraded down to below 20 MeV to irradiate nat WO 3 targets to produce 186g Re via the 186 W(p,n) nuclear reaction (Shigeta et al, 1996) The discrepancy between the proton energy calculated based on Anderson and Ziegler approach (Andersen and Ziegler, 1977) (26.3 MeV) and the practical proton energy estimated from radioisotope yield ratios (15.6 MeV) was 10.6 MeV (Fassbender et al, 2013). In this work we observe the difference of ~12 MeV between TRIM predicted E in and optimum energy.…”

Section: Resultsmentioning

confidence: 98%

Tailoring medium energy proton beam to induce low energy nuclear reactions in 86SrCl2 for production of PET radioisotope 86Y

Medvedev

Mausner

Pile

2015

Applied Radiation and Isotopes

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This paper reports results of experiments at Brookhaven Linac Isotope Producer (BLIP) aiming to investigate effective production of positron emitting radioisotope (86)Y by the low energy (86)Sr(p,n) reaction. BLIP is a facility at Brookhaven National Laboratory designed for the proton irradiation of the targets for isotope production at high and intermediate proton energies. The proton beam is delivered by the Linear Accelerator (LINAC) whose incident energy is tunable from 200 to 66 MeV in approximately 21 MeV increments. The array was designed to ensure energy degradation from 66 MeV down to less than 20 MeV. Aluminum slabs were used to degrade the proton energy down to the required range. The production yield of (86)Y (1.2+/-0.1 mCi (44.4+/-3.7) MBq/μAh) and ratio of radioisotopic impurities was determined by assaying an aliquot of the irradiated (86)SrCl2 solution by gamma spectroscopy. The analysis of energy dependence of the (86)Y production yield and the ratios of radioisotopic impurities has been used to adjust degrader thickness. Experimental data showed substantial discrepancies in actual energy propagation compared to energy loss calculations.

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“…64 Cu, 86 Y, 89 Zr and 124 I, will certainly increase. The same may be true for other potentially useful positron emitters, such as 55 Co, 71 As, 72 As and 73 Se. If the demands for those radionuclides increase further, it may become incumbent to intensively search for intermediate energy production routes leading to higher yields and purity.…”

Section: Research Orientationsmentioning

confidence: 87%

“…71]. Only in three works [72][73][74] small scale production has also been reported. A recent critical analysis [71] showed that, for obtaining a high-purity product, an enriched 186 W target is absolutely necessary and the maximum proton energy used should not exceed 18 MeV.…”

Section: Novel Low-energy β − Emittersmentioning

confidence: 99%

The present and future of medical radionuclide production

Qaim

2012

Radiochimica Acta

100

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Reactor and cyclotron production of medical radionuclides / γ -ray emitters for SPECT / Positron emitters for PET / Corpuscular radiation emitters for internal radiotherapy / Low and intermediate energy nuclear reactions / Radionuclide generators / Future directionsSummary. Medical radionuclide production technology is well established. Both reactors and cyclotrons are utilized for production; the positron emitters, however, are produced exclusively using cyclotrons. A brief survey of the production methods of most commonly used diagnostic and therapeutic radionuclides is given. The emerging radionuclides are considered in more detail. They comprise novel positron emitters and therapeutic radionuclides emitting low-range electrons and α-particles. The possible alternative production routes of a few established radionuclides, like 68 Ga and 99m Tc, are discussed. The status of standardisation of production data of the commonly used as well as of some emerging radionuclides is briefly mentioned. Some notions on anticipated future trends in the production and application of radionuclides are considered.

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Production method of no-carrier-added186Re

Cited by 56 publications

References 3 publications

Excitation functions of proton induced nuclear reactions on natW up to 40MeV

Excitation functions of proton induced nuclear reactions on natW up to 40MeV

Tailoring medium energy proton beam to induce low energy nuclear reactions in 86SrCl2 for production of PET radioisotope 86Y

The present and future of medical radionuclide production

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