Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders

Pereira, Filipe; Baptista, Rafael; Ladeiras, Diogo; Madureira, AM; Teixeira, Generosa; Rosado, Catarina; Fernandes, Ana Sofia; Ascensão, Lia; Silva, Catarina Oliveira; Reis, Catarina Pinto; Rijo, Patrícia

doi:10.1016/j.measurement.2015.07.029

Cited by 18 publications

(18 citation statements)

References 25 publications

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“…Caffeic acid (compound 4 ), luteolin-7- O -glucuronide (compound 8 ) and rosmarinic acid (compound 10 ) were positively identified by comparison with commercial standards. Rosmarinic acid has been one of the main compounds previously identified in Lavandula species [ 3 , 12 , 13 , 14 , 15 ]. Compounds 1 and 2 , 3 and 7 were identified as caffeic, p -coumaric and rosmarinic acid hexosides, based on the respective fragment ions released at m / z 179 [caffeic acid-H] − , 163 [coumaric acid-H] − and 359 [rosmarinic acid-H] − after loss of a hexosyl moiety (−162 mu).…”

Section: Resultsmentioning

confidence: 99%

“…In a study performed by Pereira et al [ 15 ], the antioxidant activity of different extracts (n-hexane, dichloromethane, ethyl acetate, methanol and water) of L. pedunculata was evaluated regarding the lipid peroxidation index (%), obtaining values that ranged from 26 to 41%. Moreover, Ferreira et al [ 23 ] tested the ethanolic extracts and decoctions of L. pedunculata using the DPPH and β-carotene inhibition methods, in which these samples revealed antioxidant activity, presenting values between 93 and 20 mg/mL, respectively.…”

Section: Resultsmentioning

confidence: 99%

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Phenolic Composition and Bioactivity of Lavandula pedunculata (Mill.) Cav. Samples from Different Geographical Origin

et al. 2018

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The aim of this study was to characterize the phenolic composition and evaluate the bioactivity of several samples of Lavandula pedunculata (Mill.) Cav, and to compare aqueous and hydroethanolic extracts. Plant materials were obtained by growing some accessions (seed samples) of various wild populations from different regions of Portugal conserved at the Portuguese Genebank in Braga. Phenolic compounds were analised by HPLC-DAD-ESI/MSn, antioxidant potential through in vitro assays (DPPH radical scavenging activity, reducing power and inhibition of lipid peroxidation), cytotoxicity on tumor cells (MCF-7, NCI-H460, HeLa and HepG2) and non-tumor (PLP2) cells, anti-inflammatory activity in rat RAW 264.7 macrophages, by the ability to inhibit NO production and antimicrobial potential by the microdilution method with INT dye (iodonitrotetrazolium chloride). Thirteen compounds were identified, being salvianolic acid B, rosmarinic acid and luteolin-7-O-glucuronide, the main compounds present, with values ranging between 44.3–582, 50.9–550, and 24.36–101.5 mg/g extract, respectively. L. pedunculata aqueous extract revealed a higher antioxidant potential (EC50 values between 14 to 530 μg/mL), which could be related to its higher concentration in phenolic compounds; however, the hydroethanolic extract showed a higher anti-inflammatory (lower EC50 values than 124 μg/mL) potential and antiproliferative capacity (lower GI50 values than 34 μg/mL). Thus, this study highlights the bioactive effects of this species and opens up possibilities of uses in food and pharmaceutical formulations. However, there are potential differences in such properties according to geographical origin of plant material, as in general, the samples from Alentejo presented higher results in all the bioactivities, compared with Trás-os-Montes samples.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Phenolic Composition and Bioactivity of Lavandula pedunculata (Mill.) Cav. Samples from Different Geographical Origin

et al. 2018

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“…luisieri and L. pedunculata ) with well‐known antioxidant activity, being rich in polyphenols and of flavonoids and rosmarinic acid ( 4 ), were selected for encapsulation in polymeric poly (lactic‐co‐glycolic) acid (PLGA) nanoparticles to improve their stability and provide a better efficiency for treatment of cutaneous diseases. The authors obtained promising results especially in term of low risks of toxicity of the produced nanoparticles …”

Section: Extracts From Selected Lamiaceae Herbs: Biological Activitiementioning

confidence: 89%

“…The authors obtained promising results especially in term of low risks of toxicity of the produced nanoparticles. [418]…”

Section: Lavendermentioning

confidence: 99%

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Napoli

Siracusa

Ruberto

2020

Chemistry & Biodiversity

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Lamiaceae is one of the largest families of flowering plants comprising about 250 genera and over 7,000 species. Most of the plants of this family are aromatic and therefore important source of essential oils. Lamiaceae are widely used as culinary herbs and reported as medicinal plants in several folk traditions. In the Mediterranean area oregano, sage, rosemary, thyme and lavender stand out for geographical diffusion and variety of uses. The aim of this review is to provide recent data dealing with the phytochemical and pharmacological studies, and the more recent applications of the essential oils and the non‐volatile phytocomplexes. This literature survey suggests how the deeper understanding of biomolecular processes in the health and food sectors as per as pest control bioremediation of cultural heritage, or interaction with human microbiome, fields, leads to the rediscovery and new potential applications of well‐known plants.

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“…Lavenders are aromatic evergreen shrubs from Lamiaceae family that have been traditionally used as culinary herbs and medicine for headaches, digestive troubles, burns, skin sores and insect bites (Pereira et al, 2015). Nowadays, the plant is extensively cultivated as ornamental plants for garden, landscape use, potpourris and essential oil production to fragrance, cosmetic, pharmaceutical, food and flavor industries (Zuzarte et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Investigations on thermal degradation of phytochemicals from lavender extract

Radu

Râpeanu

Bahrim

et al. 2020

Ann.UDJG.FoodTechnology

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The importance of lavender as a source of essential oils has been well recognized. This study reports the phytochemical profile of lavender extract in terms of chlorophylls, total carotenoids, polyphenols and flavonoids, related to antioxidant activity. The extract displayed a high polyphenolic and flavonoids content, with an antioxidant activity of 2.28±0.18 mMol Trolox/g D.W. The fractional conversion and first order kinetic models were found suitable for predicting the changes that occur in the selected phytochemicals. Kinetic and thermodynamic parameters were calculated confirming the irreversible degradation of phytochemicals. Both the temperature and duration of heating significantly impacted the content in bioactive compounds.

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Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders

Cited by 18 publications

References 25 publications

Phenolic Composition and Bioactivity of Lavandula pedunculata (Mill.) Cav. Samples from Different Geographical Origin

Phenolic Composition and Bioactivity of Lavandula pedunculata (Mill.) Cav. Samples from Different Geographical Origin

New Tricks for Old Guys: Recent Developments in the Chemistry, Biochemistry, Applications and Exploitation of Selected Species from the Lamiaceae Family

Investigations on thermal degradation of phytochemicals from lavender extract

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