Prodromal Symptoms and Intermittent Drug Medication in Mood Disorders

Fava, Giovanni A.; Molnar, G.; Grandi, Silvana; Sonino, Nicoletta

doi:10.1055/s-2007-1014429

Cited by 11 publications

(23 citation statements)

References 5 publications

(5 reference statements)

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“…The study closely followed a sample of clinically stable patients who were highly conscious of their illness and had very cooperative families [39]. Another option that has been proposed is to eliminate maintenance medication and replace it with prodrome monitoring [2]. This approach has yielded good results in some cases [40], but in other studies five patients were similarly followed during 2 years [39], three of them relapsing and one experiencing significant symptoms.…”

Section: Discussionmentioning

confidence: 99%

Prodromal Symptoms to Relapse in Bipolar Disorder

Sierra

Livianos

Arques

et al. 2007

Aust N Z J Psychiatry

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In a cyclical and recurring illness such as bipolar disorder, prodrome detection is of vital importance. This paper describes manic and depressive prodromal symptoms to relapse, methods used in their detection, problems inherent in their assessment, and patients' coping strategies. A review of the literature on the issue was performed using MEDLINE and EMBASE databases (1965-May 2006). 'Bipolar disorder', 'prodromes', 'early symptoms', 'coping', 'manic' and 'depression' were entered as key words. A hand search was conducted simultaneously and the references of the articles found were used to locate additional articles. The most common depressive prodromes are mood changes, psychomotor symptoms and increased anxiety; the most frequent manic prodromes are sleep disturbances, psychotic symptoms and mood changes. The manic prodromes also last longer. Certain psychological interventions, both at the individual and psychoeducational group level, have proven effective, especially in preventing manic episodes. Bipolar patients are highly capable of detecting prodromal symptoms to relapse, although they do find the depressive ones harder to identify. Learning detection, coping strategies and idiosyncratic prodromes are elements that should be incorporated into daily clinical practice with bipolar patients.

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Section: Discussionmentioning

confidence: 99%

Prodromal Symptoms to Relapse in Bipolar Disorder

Sierra

Livianos

Arques

et al. 2007

Aust N Z J Psychiatry

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“…Recurrence of depression in the case vignette can also be managed by treatment of the new episode with the same or other antidepressant and discontinuation when remission ensues [36]. The appearance of prodromal symptoms generally precedes the full syndrome by weeks or months [36].…”

Section: Therapeutic Strategiesmentioning

confidence: 99%

“…The appearance of prodromal symptoms generally precedes the full syndrome by weeks or months [36]. An early intervention upon relapse was found to significantly shorten the length of the depressive episode [37].…”

Section: Therapeutic Strategiesmentioning

confidence: 99%

“…An early intervention upon relapse was found to significantly shorten the length of the depressive episode [37]. As a result, relatively frequent follow-up visits and education of patients and their family members to recognize the patient’s characteristic prodromal symptoms (which appear to be similar across episodes of the same patient) may potentially increase the efficacy of this approach [36]. This treatment, which is in line with approaches to recurrent disorders in clinical medicine, requires the establishment of a good patient-doctor relationship and a lower degree of compliance compared with the long-term pharmacotherapy.…”

Section: Therapeutic Strategiesmentioning

confidence: 99%

See 1 more Smart Citation

Management of Recurrent Depression in Primary Care

Fava

Ruini²,

Sonino³

2002

Psychother Psychosom

Self Cite

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“…Other papers (e.g. review articles, letters) in which the CID was used or cited will not be discussed in detail [12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81]. …”

Section: Resultsmentioning

confidence: 99%

The Clinical Interview for Depression: A Comprehensive Review of Studies and Clinimetric Properties

Guidi

Fava

Bech

et al. 2010

Psychother Psychosom

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Background: A comprehensive assessment of the wide spectrum of depressive symptomatology, particularly in its subclinical forms, is lacking in standard rating scales. There is also an emerging need for instruments that can detect small differences in therapeutic studies and have good sensitivity. The purpose of this paper is to review the clinimetric characteristics of Paykel’s Clinical Interview for Depression (CID) and to examine the results of the studies in which the interview has been used. Methods: Published reports which involved the use of the CID were identified by searching the following electronic databases: Medline, PsychINFO, EMBASE, and Web of Science. A manual search of the literature was also performed. Results: The initial strategies yielded 169 published reports for potential inclusion in the review: 98 are discussed here. The CID has been used extensively in a variety of studies, including descriptive studies, classification by means of factor analysis and cluster analysis, and predictor variables of response to treatment or relapse. The CID has also been used as an outcome measure in several controlled clinical trials and follow-up studies of pharmacotherapy and psychotherapy of affective disorders. It has been shown to be valid and reliable, to discriminate depressives from controls, or different subgroups of depressed patients, and to reflect changes during the course of treatment, particularly when individual symptoms are considered. Conclusions: Evidence from these studies highlights the utility of the CID in clinical research and practice. Its clinimetric characteristics, particularly the broad evaluation of affective symptomatology and the sensitivity to change, make it an instrument of choice in therapeutic trials.

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Prodromal Symptoms and Intermittent Drug Medication in Mood Disorders

Cited by 11 publications

References 5 publications

Prodromal Symptoms to Relapse in Bipolar Disorder

Prodromal Symptoms to Relapse in Bipolar Disorder

Management of Recurrent Depression in Primary Care

The Clinical Interview for Depression: A Comprehensive Review of Studies and Clinimetric Properties

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