Processing and Food Safety

Rawles, Dafne D.; Fernandes, Custy F.; Flick, George J.; Ammerman, Gale R.

doi:10.1016/s0167-9309(97)80015-4

Striped Bass and Other Morone Culture

1997

DOI: 10.1016/s0167-9309(97)80015-4

|View full text |Cite

Processing and Food Safety

Dafne D. Rawles¹,

Custy F. Fernandes²,

George J. Flick³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2004

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, histamine may also cause physiological conditions such as nausea, sweating, headache, and hypertension when its regulation is altered. [1][2][3] Measurement of histamine in blood and urine serves as one of the important clinical parameters in various diseases such as asthma, anaphylaxis, hives, mastocytosis and cancer. [4][5][6][7][8][9] A number of analytical methods have been developed to determine histamine in foodstuffs and biological samples.…”

mentioning

confidence: 99%

Assay of histamine by nano‐liquid chromatography/tandem mass spectrometry with a packed nanoelectrospray emitter

Song

Quan

Liu

2004

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

A nano-liquid chromatographic /tandem mass spectrometric (nanoHPLC/MS/MS) method has been developed for the sensitive determination of histamine, a vital neurotransmitter. The method involved pre-column derivatization of histamine with 7-fluoro-4-nitrobenzoxadiazole (NBD-F), thus increasing the hydrophobicity of the analyte and allowing it to be retained and stacked on a nanoelectrospay emitter packed with C18 reversed-phase particles. Sodium 1-heptanesulfonate, added as an ion-pairing reagent in the mobile phase for sample loading, was found to facilitate greatly the analyte retention. The packed nanoelectrospray emitter was easily prepared using fused-silica capillary of 75 microm i.d., and included creating an electrospray emitter tip and then slurry-packing a 5 cm long column with 5 microm silica-based particles. After sample loading, the mobile phase was changed for separation and a characteristic precursor-to-product ion transition, m/z 275 --> 258, was used for the quantification. A linear calibration curve in the range from 1.0-100 ng/mL histamine with an r2 value of 0.9995 was obtained. The detection limit was estimated to be 0.1 ng/mL histamine in water. In a preliminary validation, the method was applied to determine histamine in alcoholic beverages and rat brain tissues.

show abstract

mentioning

confidence: 99%

Assay of histamine by nano‐liquid chromatography/tandem mass spectrometry with a packed nanoelectrospray emitter

Song

Quan

Liu

2004

Rapid Comm Mass Spectrometry

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Processing and Food Safety

Cited by 1 publication

References 27 publications

Assay of histamine by nano‐liquid chromatography/tandem mass spectrometry with a packed nanoelectrospray emitter

Assay of histamine by nano‐liquid chromatography/tandem mass spectrometry with a packed nanoelectrospray emitter

Contact Info

Product

Resources

About