Process optimization of deep eutectic solvent-based microwave-assisted extraction of flavonoids from Ziziphi Spinosae Semen using response surface methodology
Abstract:Total flavonoids were extracted from Ziziphi Spinosae Semen (ZSS) by applying microwave-assisted extraction with low eutectic solvent (DES) as the extractant. This study investigated the effect of 21 different components of DES on the yield of total flavonoids in ZSS. The results revealed that the DES system, which consists of choline chloride and lactic acid with a molar ratio of 2:1, achieved the best flavonoid extraction efficiency. Based on the single-factor test, response surface methodology was used to o… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.