2003
DOI: 10.1055/s-2003-42050
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Process Development of 1,2-Benzisothiazolin-3(2H)-one by Replacing of the Toxic Materials

Abstract: 1,2-Benzisothiazolin-3(2H)-one (2) was synthesized by 2,2¢-dithiodibenzoic acid (1) with acetamide or urea in high yield via one-pot amidation-cyclization process.

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