“…As confirmed by safety assessment evaluated by RC1 calorimetry, the heat output of the amide formation stayed constant during the addition of the acyl chloride, characteristic of a fast reaction with no potential for latent reaction. 2 10. Physical properties and spectral data for 2 are as follows: mp 106-107 °C; 1 H NMR (600 MHz, CDCl 3 ) : 2.77 (d, J = 4.9 Hz, 3 H), 3.53 (s, 2 H), 5.43 (bs, 1 H), 7.20 (d, J = 8.4 Hz, 2 H), 7.33 (d, J = 8.4 Hz, 2 H); 13 11.…”