Abstract:Hypoxic ischaemic encephalopathy (HIE), an important complication of perinatal asphyxia, remains a major health burden. Neonates are classifi ed using the Sarnat score and neonates >35 weeks with moderate/ severe HIE are treated with therapeutic hypothermia (TH). TH improves survival/ decreases disability however 30-50% of mild HIE cases (not offered TH) develop cognitive impairment. Early biomarkers are vital to redefi ne HIE and better manage these infants. Cerebral monitoring is essential to establish cereb… Show more
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