Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation

Abstract

The deep brain stimulation (DBS) Think Tank X was held on August 17–19, 2022 in Orlando FL. The session organizers and moderators were all women with the theme women in neuromodulation. Dr. Helen Mayberg from Mt. Sinai, NY was the keynote speaker. She discussed milestones and her experiences in developing depression DBS. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers (from industry and academia) can freely discuss current and emerging DBS technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank X speakers was that DBS has continued to expand in scope however several indications have reached the “trough of disillusionment.” DBS for depression was considered as “re-emerging” and approaching a slope of enlightenment. DBS for depression will soon re-enter clinical trials. The group estimated that globally more than 244,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. This year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia, and Australia; cutting-edge technologies, closed loop DBS, DBS tele-health, neuroethics, lesion therapy, interventional psychiatry, and adaptive DBS.

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“…1) in 1993, in Grenoble, France, DBS as a method for both therapy and research has undergone a tremendous—and ongoing—spread not only to many countries on the planet, but also to many areas in the cerebrum and cerebellum, for treatment of several brain diseases 2 . According to the latest estimates more than 244,000 patients worldwide have received DBS, 3 the great majority of them for treatment of PD and other movement disorders 2 . Within a few years of its introduction, especially after the publication by Limousin et al's 4 paper in The New England Journal of Medicine in 1998, STN DBS replaced the previously widespread posteroventral pallidotomy of Laitinen, which had inaugurated the renaissance of surgery for post‐levodopa PD 5 .…”

Thirty Years of Global Deep Brain Stimulation: “Plus ça change, plus c’est la même chose”?

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