“…[1][2][3][4][5][6][7] The dissociative agent ketamine maintains cardiopulmonary stability [8][9][10] but can result in extended recovery, emesis, hypersalivation, and hallucinations. 6,8,[10][11][12][13] The popular combination of propofol and ketamine ("ketofol") is purported to reduce respiratory depression, emesis, and recovery time by counteracting the negative effects of one drug with the positive effects of the other, 11,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] although the best evidence thus far does not indicate a reduction in airway and respiratory adverse events relative to propofol alone.…”