Procaine and S-adenosyl-L-homocysteine (SAH) affect the expression of genes related to the epigenetic machinery and change the DNA methylation status ofin vitrocultured bovine skin fibroblasts

Abstract

2 related to the epigenetic machinery and change the DNA methylation status of in 3 vitro cultured bovine skin fibroblasts 4 5 Abstract 42 bovine cell culture was able to alter the epigenetic profile of the cells. This approach 43 may be a useful alternative strategy to improve the efficiency of reprogramming the 44 somatic nuclei after fusion, which in turn will improve the SCNT efficiency. 45 3 46 47